Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Da-lei Wu"'
Docking-guided rational engineering of a macrolide glycosyltransferase glycodiversifies epothilone B
Autor:
Peng Zhang, Lijuan Zhang, Xukai Jiang, Xiao-tong Diao, Shuang Li, Dan-dan Li, Zheng Zhang, Junqiang Fang, Ya-jie Tang, Da-lei Wu, Changsheng Wu, Yue-zhong Li
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-11 (2022)
Zhang et al. identify three hot regions of macrolide glycosyltransferase BsGT-1, that can play a role in epothilone B and sugar donor specificity. Further mutagenesis of BsGT-1 showed that specificity could be engineered and when the mutations were i
Externí odkaz:
https://doaj.org/article/dee3c165cd3f49388524a75c04cf1e4d
Publikováno v:
Acta pharmacologica Sinica. 43(10)
Transcription factors (TFs) specifically bind to DNA, recruit cofactor proteins and modulate target gene expression, rendering them essential roles in the regulation of numerous biological processes. Meanwhile, mutated or dysregulated TFs are involve
Publikováno v:
Acta Pharmacol Sin
Autor:
You-Ping, Li, Ya, Tang, Zhong-Yu, Fan, Min, Pu, Jin-Lian, Zhang, Zheng-Zheng, Yang, Da-Lei, Wu
Publikováno v:
Huan jing ke xue= Huanjing kexue. 39(2)
Volatile organic compounds (VOCs) were measured in atmospheric samples collected from urban and roadside atmospheric environments in Chengdu in September 2012. The composition, chemical reactivity, and concentration level and its variation characteri
Publikováno v:
Experimental and Therapeutic Medicine
Cleidocranial dysplasia (CCD) is a rare autosomal dominant condition that affects ossification. The dental abnormalities associated with CCD present an obstacle to orthodontic treatment planning. Early diagnosis is crucial to provide the patient with
Publikováno v:
Experimental & Therapeutic Medicine; Aug2016, Vol. 12 Issue 2, p690-694, 5p
Publikováno v:
Journal of Theoretical & Computational Chemistry; Mar2007, Vol. 6 Issue 1, p63-80, 18p