Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Da-jun Yang"'
Autor:
Wei Chen, Kai-Bin Yang, Yuan-Zhe Zhang, Zai-Shan Lin, Jin-Wei Chen, Si-Fan Qi, Chen-Fei Wu, Gong-Kan Feng, Da-Jun Yang, Ming Chen, Xiao-Feng Zhu, Xuan Li
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-20 (2024)
Abstract Background High expression of ubiquitin ligase MDM2 is a primary cause of p53 inactivation in many tumors, making it a promising therapeutic target. However, MDM2 inhibitors have failed in clinical trials due to p53-induced feedback that enh
Externí odkaz:
https://doaj.org/article/36aa2479810046219abd7234f4f5e8a9
Autor:
Qiu-yun Luo, Tian Di, Miao-Zhen Qiu, Zeng-fei Xia, Yong Du, Run-duan Lin, Li-qiong Yang, Yu-ting Sun, Da-Jun Yang, Jian Sun, Lin Zhang
Publikováno v:
Cancer Cell International, Vol 22, Iss 1, Pp 1-10 (2022)
Abstract Background Esophageal squamous cell carcinoma (ESCC) is a severe disease with high mortality, and is associated with poor prognosis and frequent lymphatic metastasis. Therefore, prognostic indicators for ESCC are urgently needed. A-kinase an
Externí odkaz:
https://doaj.org/article/48c06573b6034c0998fcce7d460fbf17
Autor:
Fan Luo, Fei-Teng Lu, Miao-Zhen Qiu, Ting Zhou, Wen-Juan Ma, Min Luo, Kang-Mei Zeng, Qiu-Yun Luo, Wen-Tao Pan, Lin Zhang, Zeng-Fei Xia, Zhong-Han Zhang, Jia-Xin Cao, Hong-Yun Zhao, Li Zhang, Da-Jun Yang
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-14 (2021)
Abstract Advanced nasopharyngeal carcinoma (NPC) has a poor prognosis, with an unfavorable response to palliative chemotherapy. Unfortunately, there are few effective therapeutic regimens. Therefore, we require novel treatment strategies with enhance
Externí odkaz:
https://doaj.org/article/c8fd1d13c348483b94e5ed6a0209e578
Autor:
Hanjie Yi, Miao‐Zhen Qiu, Luping Yuan, Qiuyun Luo, Wentao Pan, Suna Zhou, Lin Zhang, Xianglei Yan, Da‐Jun Yang
Publikováno v:
Cancer Medicine, Vol 9, Iss 12, Pp 4197-4206 (2020)
Abstract Gastric carcinoma is the third major cause of cancer‐related death in China. Bcl‐2 and other BH3 family proteins are critically important in the process of apoptosis pathway, which may be a promising target. APG‐1252‐M1 specifically
Externí odkaz:
https://doaj.org/article/6d3d315277894e3ab1c21328cee0f491
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-12 (2019)
Abstract Background Bcl-2 family members play an important role in the development of malignant lymphoma and can induce drug resistance in anticancer treatment. The development of small molecules targeting Bcl-2 family proteins may be a new strategy
Externí odkaz:
https://doaj.org/article/408bc3743c7b47b39f3819f51dce8889
Autor:
Miao-Zhen Qiu, Cai-Yun He, Da-Jun Yang, Da-Lei Zhou, Bai-Wei Zhao, Xiao-Jian Wang, Li-Qiong Yang, Shi-Xun Lu, Feng-Hua Wang, Rui-Hua Xu
Publikováno v:
Therapeutic Advances in Medical Oncology, Vol 12 (2020)
Background: Epstein–Barr virus-associated gastric cancer (EBVaGC) has unique clinicopathologic features and our present understanding of its treatment outcome is limited. Here, we investigated the clinical outcomes of resectable and metastatic EBVa
Externí odkaz:
https://doaj.org/article/6e48793299e94940948711b07ad5d041
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Increasing evidences from phase II or III trials have proved that salvage systematic therapy, including chemotherapy, target therapy, or checkpoint inhibitor therapy can prolong survival in patients who do not succeed with second line the
Externí odkaz:
https://doaj.org/article/67c5894700fb45d2a200a00207a13230
Autor:
Bao-Xia Li, Heng-Bang Wang, Miao-Zhen Qiu, Qiu-Yun Luo, Han-Jie Yi, Xiang-Lei Yan, Wen-Tao Pan, Lu-Ping Yuan, Yu-Xin Zhang, Jian-Hua Xu, Lin Zhang, Da-Jun Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-6 (2018)
In the publication of this article [1], there was an error in Figs. 2, 3 and 6.
Externí odkaz:
https://doaj.org/article/3e7542f694584a06943ff63099834c8a
Autor:
Hanjie Yi, Xianglei Yan, Qiuyun Luo, Luping Yuan, Baoxia Li, Wentao Pan, Lin Zhang, Haibo Chen, Jing Wang, Yubin Zhang, Yifan Zhai, Miao-Zhen Qiu, Da-Jun Yang
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 37, Iss 1, Pp 1-10 (2018)
Abstract Background Gastric cancer is the leading cause of cancer related death worldwide. Radiation alone or combined with chemotherapy plays important role in locally advanced and metastatic gastric adenocarcinoma. MDM2–p53 interaction and downst
Externí odkaz:
https://doaj.org/article/741ca8ab6c9e4e2bb0e4bb81ca774357
Autor:
Miao‐Zhen Qiu, Wen‐Tao Pan, Jun‐Zhong Lin, Zi‐Xian Wang, Zhi‐Zhong Pan, Feng‐Hua Wang, Da‐Jun Yang, Rui‐Hua Xu
Publikováno v:
Cancer Medicine, Vol 7, Iss 4, Pp 1141-1150 (2018)
Abstract Mountain of studies has showed that right‐sided colon cancer (RSCC) and left‐sided colon cancer (LSCC) have different clinical presentation and biologic features and should be considered as two distinct disease entities. The survival dif
Externí odkaz:
https://doaj.org/article/29cf062435814b758d366e588ef6a4a1