Zobrazeno 1 - 10
of 31
pro vyhledávání: '"Da-Yuan Wang"'
Autor:
Guang Yang, Da-Yuan Wang, Yong Liu, Fan Huang, Shuang Tian, Yijin Ren, Jianfeng Liu, Yingli An, Henny C. van der Mei, Henk J. Busscher, Linqi Shi
Publikováno v:
Bioactive Materials, Vol 14, Iss , Pp 321-334 (2022)
Cascade-reaction chemistry can generate reactive-oxygen-species that can be used for the eradication of infectious biofilms. However, suitable and sufficient oxygen sources are not always available near an infection site, while the reactive-oxygen-sp
Externí odkaz:
https://doaj.org/article/e198b1d437f34f96bc64dc196459a07e
Publikováno v:
Molecules, Vol 27, Iss 22, p 7925 (2022)
(1) Background: Nuclear factor κB (NF-κB) is an important transcriptional regulator that regulates the inflammatory pathway and plays a key role in cellular inflammatory and immune responses. The presence of a high concentration of NF-κB is positi
Externí odkaz:
https://doaj.org/article/dd181d8160c543dc873fd1cef83853d3
Publikováno v:
Frontiers in Chemistry, Vol 7 (2020)
Many nanotechnology-based antimicrobials and antimicrobial-delivery-systems have been developed over the past decades with the aim to provide alternatives to antibiotic treatment of infectious-biofilms across the human body. Antimicrobials can be loa
Externí odkaz:
https://doaj.org/article/b4594525de814185b23fbe6c8e160a55
Autor:
Da-Yuan Wang, Guang Yang, Xiao-Xiao Zhang, Henny C. van der Mei, Yijin Ren, Henk J. Busscher, Linqi Shi
Publikováno v:
Journal of Controlled Release, 352, 460-471. Elsevier Bedrijfsinformatie b.v.
Exposure of infectious biofilms to dispersants induces high bacterial concentrations in blood that may cause sepsis. Preventing sepsis requires simultaneous biofilm dispersal and bacterial killing. Here, self-targeting DCPA(2-(4-((1,5-bis(octadecenoy
Autor:
Da‐Yuan Wang, Yuanlong Cao, Guang Yang, Siyu Zhang, Henny C. van der Mei, Yijin Ren, Theo G. van Kooten, Derk‐Jan A. de Groot, Jacco J. de Haan, Linqi Shi, Henk J. Busscher
Publikováno v:
Advanced Functional Materials.
Autor:
Da-Yuan Wang, Linzhu Su, Guang Yang, Yijin Ren, Mingqing Zhang, Haoren Jing, Xipeng Zhang, Roger Bayston, Henny C. van der Mei, Henk J. Busscher, Linqi Shi
Publikováno v:
Journal of materials chemistry b. 10(14):2316-2322
Self-targeting antimicrobial platforms have yielded new possibilities for the treatment of infectious biofilms. Self-targeting involves stealth transport through the blood circulation towards an infectious biofilm, where the antimicrobial platform pe
Publikováno v:
Angewandte Chemie (International Ed. in English)
Angewandte Chemie-International Edition, 60(32), 17714-17719. WILEY-V C H VERLAG GMBH
Angewandte Chemie-International Edition, 60(32), 17714-17719. WILEY-V C H VERLAG GMBH
A lipid named DCPA was synthesized under microwave‐assisted heating. DCPA possesses a pyridine betaine, hydrophilic group that can be complexed with water through hydrogen bonding (DCPA‐H2O). DCPA‐H2O liposomes became protonated relatively fast
Publikováno v:
Biomaterials science. 10(13)
Protein therapeutics have been viewed as powerful candidates for cancer treatment by virtue of highly specific bioactivity and minimized adverse effects. However, the intracellular delivery of protein drugs remains enormously challenging due to multi
Autor:
Jie Shen, Peng George Wang, Qingqing Huang, Yanke Kang, Wenhui Lv, Qiuyu Wang, Han Jinghua, Li Meng, Jing Li, Da-Yuan Wang, Zihan Luo, Wang Yajie, Yanming Wang
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 28(4)
We designed, synthesized, and characterized a tri-block copolymer. Its hydrophobic part, a chain of histone deacetylase inhibitor (HDACi) prodrug, was symmetrically flanked by two identical PEG blocks, whereas the built-in HDACi was a linear molecule
Publikováno v:
Bioorganicmedicinal chemistry letters. 30(24)
Hypoxia-inducible factor 1α (HIF-1α) is a known regulator of tumor cell proliferation, migration, and angiogenesis. The presence of a high concentration of HIF-1α is positively correlated with the severity of cancer. Therefore, the inhibition of t