Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Da-Xing Xie"'
Autor:
Yongdong Feng, Jia Hu, Deding Tao, Xiping Li, Da-Xing Xie, Jianping Gong, Jianquan Yao, Peng Zhang, Jianli Wu
Publikováno v:
Cell Proliferation. 41:265-278
Objectives: Based on studies of unicellular organisms or cultured mammalian cells, the generally accepted model of cell‐cycle regulation has been developed in which sequential (scheduled) expression of cyclins D, E, A and B and activation of Cdk2 a
Publikováno v:
The Chinese-German Journal of Clinical Oncology. 6:P296-P299
Objective To investigate the feasibility of chemosensitivity testing of antitumor drugs by flow cytometry in clinical applications so as to provide experimental and theoretical basis for the establishment of a novel antitumor drugs sensitivity testin
Autor:
Qinglei Gao, Ding Ma, Gang Chen, Liang Zhuang, Jingniu Deng, Yunping Lu, Da-xing Xie, Xiaoyuan Huang, Kanyan Li, Jianfeng Zhou
Publikováno v:
Clinical Cancer Research. 11:8431-8440
Purpose: Polo-like kinase 1 (plk1) is a serine/threonine protein kinase essential for multiple mitotic processes. Previous observations have validated plk1 as a promising therapeutic target. Despite being conceptually attractive, the potency and spec
Autor:
Xiaolan Li, Deding Tao, Xiangyang Wang, Yixin Tong, Jianping Gong, Da-Xing Xie, Jiang Min, Junbo Hu
Publikováno v:
Cytometry. Part A : the journal of the International Society for Analytical Cytology. 81(10)
It is widely assumed that during the mammalian cell cycle, four major cyclins, including G1 cyclins (D, E) and mitotic cyclins (A, B1), are expressed in an orderly scheduled pattern in exponentially cultured cells. In high-density cultured cells and
Publikováno v:
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 31(11)
To investigate the changes in cell cycle induced by cisplatin (DDP) and the effect of antisense oligonucleotide (AsODN) targeting Chk1/2 on DDP-induced apoptosis in lung cancer cell line A549 cells.The characteristics of cell cycle and apoptosis indu
Publikováno v:
Zhonghua zhong liu za zhi [Chinese journal of oncology]. 31(3)
To explore the increasing effect of blocking Chk1 and /or Chk2 gene by Chk1 or Chk2-specific antisense oligodeoxynucleotides (AsODN) on apoptosis in HeLa cell line after irradiation and its mechanism of action.Asynchronized HeLa cells were exposed to
Publikováno v:
Ai zheng = Aizheng = Chinese journal of cancer. 25(10)
Cell cycle specificity, an important feature of anticancer drugs, is commonly used in the design of combined chemotherapy. Paclitaxel is widely accepted as an G2/M phase-specific agent. However, cumulative evidences revealed that the cell cycle speci
Publikováno v:
Ai zheng = Aizheng = Chinese journal of cancer. 25(5)
Chondriosome-mediated apoptosis is closely related to cell cycle, however, the correlation of receptor-mediated apoptosis to cell cycle progression is unclear yet. This study was to observe the receptor-mediated apoptosis and cell cycle specificity i
Autor:
Hui-Ling, Tan, Yong-Dong, Feng, De-Ding, Tao, Hui, Xiao, Da-Xing, Xie, Cong-Nian, Yu, Jian-Ping, Gong
Publikováno v:
Ai zheng = Aizheng = Chinese journal of cancer. 24(12)
Caffeine could act on cell cycle checkpoints and affect the progression of cell cycle, but its impact on apoptosis of tumor cells is in debate. This study was carried out to investigate the effects of caffeine on camptothecin-induced apoptosis and ce
Publikováno v:
Ai zheng = Aizheng = Chinese journal of cancer. 24(9)
Eukaryotic cell cycle events progress strictly in order which is controlled by the mechanism of checkpoint. At present, most analyses of checkpoint use the flow cytometry (FCM) based on DNA histogram to detect cell cycle distribution. This study was