Zobrazeno 1 - 10
of 195
pro vyhledávání: '"Da-Hye Lee"'
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Abstract Autophagy maintains cellular homeostasis during low energy states. According to the current understanding, glucose-depleted cells induce autophagy through AMPK, the primary energy-sensing kinase, to acquire energy for survival. However, cont
Externí odkaz:
https://doaj.org/article/bd30e84def52421a9b4ba2b2b0d64198
Publikováno v:
PLoS ONE, Vol 18, Iss 5, p e0284344 (2023)
ObjectiveAlcohol intake is a major risk factor for various diseases. Elucidating alcohol use disorder (AUD) is important in preventing diseases and promoting health. We aimed to investigate the effect of art therapy on emotional (Minnesota Multiphasi
Externí odkaz:
https://doaj.org/article/934cb5bcdd1e4b1b856b64ae194c6d22
Publikováno v:
BMC Neuroscience, Vol 22, Iss 1, Pp 1-11 (2021)
Abstract Background The receptor for advanced glycation end-products (RAGE) is involved in neuroinflammation. This study investigated the changes in RAGE expression following noise-induced hearing loss. Methods Three-week-old female Sprague–Dawley
Externí odkaz:
https://doaj.org/article/91e6aaa2925a4233b0a90cb8f0c52b18
Autor:
Hee Sun Park, Da‐Hye Lee, Da Hyun Kang, Min‐Kyung Yeo, Goeun Bae, Dahye Lee, Geon Yoo, Ju‐Ock Kim, Eunyoung Moon, Yang Hoon Huh, Sang‐Hee Lee, Eun‐Kyeong Jo, Sang Yeon Cho, Jeong Eun Lee, Chaeuk Chung
Publikováno v:
Cancer Medicine, Vol 10, Iss 4, Pp 1405-1417 (2021)
Abstract Background Despite the progress of advanced target therapeutic agents and immune checkpoint inhibitors, EGFR‐TKI resistance is still one of the biggest obstacles in treating lung cancer. Clinical studies with autophagy inhibitors are activ
Externí odkaz:
https://doaj.org/article/a2cdcb63bb434dbb85106624db51f621
Publikováno v:
BMC Neuroscience, Vol 21, Iss 1, Pp 1-10 (2020)
Abstract Background This study aimed to investigate the changes in molecules related to perineuronal nets (PNNs) and synaptic transporters in the primary auditory cortices of rats with noise-induced hearing loss. Female Sprague–Dawley rats at postn
Externí odkaz:
https://doaj.org/article/b9859fc9578848f8890faa65affb9659
Autor:
Sung Yong Choi, Hosung Bae, Sun-Hye Jeong, Intae Park, Hyunsoo Cho, Seon Pyo Hong, Da-Hye Lee, Choong-kun Lee, Jin-Sung Park, Sang Heon Suh, Jeongwoon Choi, Myung Jin Yang, Jeon Yeob Jang, Lucas Onder, Jeong Hwan Moon, Han-Sin Jeong, Ralf H. Adams, Jin-Man Kim, Burkhard Ludewig, Joo-Hye Song, Dae-Sik Lim, Gou Young Koh
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-15 (2020)
Fibroblastic reticular cells (FRC) are important for lymph node (LN) structure and function. Here the authors show that the YAP/TAZ complex downstream of Hippo signalling regulates FRC commitment and maturation, with YAP/TAZ deficiency impairing FRC
Externí odkaz:
https://doaj.org/article/354526f25abf44f89bb47da409f5948a
Publikováno v:
SAGE Open Medical Case Reports, Vol 9 (2021)
Spontaneous regression of lung cancer is exceptionally rare. But there have been several intriguing cases reported in early and even advanced stages of lung cancer. Although the exact mechanism remains to be elucidated, the inflammation and immunolog
Externí odkaz:
https://doaj.org/article/4bd06b4448e84d0e9fd92b1f8d2aece2
Iridoids of Valeriana fauriei contribute to alleviating hepatic steatosis in obese mice by lipophagy
Autor:
Da-Hye Lee, So-Hyun Park, Yang Hoon Huh, Min Jung Kim, Hyo-Deok Seo, Tae-Youl Ha, Jiyun Ahn, Young-Jin Jang, Chang Hwa Jung
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 125, Iss , Pp 109950- (2020)
Nonalcoholic fatty liver disease (NAFLD) is a common risk factor for metabolic syndrome that increases the risk of future cardiovascular disease, stroke, and diabetes. Recently, autophagy has been proposed as a means to prevent NAFLD. We investigated
Externí odkaz:
https://doaj.org/article/914762d5a6fb4de191f6cef11a90f0b7
Autor:
Da-Hye Lee, Jae Oh Park, Tae-Shin Kim, Sang-Kyum Kim, Tack-hoon Kim, Min-chul Kim, Gun Soo Park, Jeong-Hwan Kim, Shinji Kuninaka, Eric N. Olson, Hideyuki Saya, Seon-Young Kim, Ho Lee, Dae-Sik Lim
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
The Hippo pathway regulates the differentiation of stem and progenitor cells, but it is unclear how it acts in liver development. Here, the authors knockout Hippo pathway components Lats1 and 2in the liver, causing suppression of hepatocyte different
Externí odkaz:
https://doaj.org/article/608124d888234a85a5fb09ba2ac76500
Autor:
Da-Hye Lee, Eun-Joo Jeon, Jiyun Ahn, Jin-Taek Hwang, Jinyoung Hur, Tae-Youl Ha, Chang Hwa Jung, Mi Jeong Sung
Publikováno v:
Journal of Functional Foods, Vol 23, Iss , Pp 105-114 (2016)
Limonin, the most prevalent limonoid in citrus fruits, is widely used as a dietary supplement because of its biological activities. Although studies have shown that limonin inhibits bone resorption in osteoclasts and improves bone quality in orchidec
Externí odkaz:
https://doaj.org/article/8b0603a84b0c4a2db0cbe0911c4d0302