Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Da-Gong Wang"'
Autor:
Maurizio Voi, Xiong Cai, Hai-Xiao Zhai, Mylissa Borek, Steven DellaRocca, Anna Wai See Ma, Brian Zifcak, Maria Samson, Ling Yin, Hui Qu, Ruzanna Atoyan, Guang-Xin Xu, Jing Wang, Da-Gong Wang, Rudi Bao, Cheng-Jung Lai, Changgeng Qian
PDF file, 348KB, Figure S1. Synergy between PI3K and HDAC pathway inhibition. Figure S2. CUDC-907 increases acetylation of histone H3 in cultured cancer cells. Figure S3. CUDC-907 increases tubulin acetylation in cultured cancer cells. Figure S4. CUD
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32848b021e6bbc17f583b7bdf8d37c66
https://doi.org/10.1158/1078-0432.22445738.v1
https://doi.org/10.1158/1078-0432.22445738.v1
Autor:
Maurizio Voi, Xiong Cai, Hai-Xiao Zhai, Mylissa Borek, Steven DellaRocca, Anna Wai See Ma, Brian Zifcak, Maria Samson, Ling Yin, Hui Qu, Ruzanna Atoyan, Guang-Xin Xu, Jing Wang, Da-Gong Wang, Rudi Bao, Cheng-Jung Lai, Changgeng Qian
Purpose: Given that histone deacetylase (HDAC) inhibitors are known to induce multiple epigenetic modifications affecting signaling networks and act synergistically with phosphatidylinositol 3-kinase (PI3K) inhibitors, we developed a strategy to simu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::57468279c708b76d5357a1cc33f8026e
https://doi.org/10.1158/1078-0432.c.6520553
https://doi.org/10.1158/1078-0432.c.6520553
Publikováno v:
The American Journal of Pathology. 164:1727-1737
Phosphorylation of proteins on serine or threonine residues preceding proline (pSer/Thr-Pro) is a major regulatory mechanism in cell proliferation and transformation. Interestingly, the pSer/Thr-Pro motifs in proteins exist in two distinct cis and tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbe28d4ebf8236bcd7ee82c28c58854c
https://doi.org/10.1016/s0002-9440(10)63731-5
https://doi.org/10.1016/s0002-9440(10)63731-5
Autor:
Da-Gong Wang
Publikováno v:
Clinical Endocrinology. 51:1-9
Acquired resistance to apoptosis in neuroendocrine tumours (NETs) may promote clonal expansion and enhance the likelihood that subsequent mutations lead to growth or persistence of the neoplastic clone. Recent studies have demonstrated that deregulat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f0a1bb6fb1396e650ec36a86fa61b60f
https://doi.org/10.1046/j.1365-2265.1999.00756.x
https://doi.org/10.1046/j.1365-2265.1999.00756.x
Autor:
Da-Gong Wang, Keith D. Buchanan, Fionnuala Lundy, R.T. Cunningham, Colin F. Johnston, Wei-Hua Liu, Kathy M. Pogue
Publikováno v:
The Journal of Pathology. 184:408-413
Medullary thyroid carcinoma (MTC) is an uncommon tumour of calcitonin-secreting C-cells of the thyroid gland. This cancer represents an important potential model for the study of mechanisms of human epithelial cell transformation. Although recent stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8311cf0ec20afc482c839aca5c83ecdd
https://doi.org/10.1002/(sici)1096-9896(199804)184:4<408::aid-path1222>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199804)184:4<408::aid-path1222>3.0.co
Publikováno v:
The Journal of Pathology. 184:247-251
Several genetic aberrations have been implicated in the carcinogenesis of small cell lung carcinomas (SCLCs), including tumour suppressor gene p53 deletion and mutation and amplification of the myc family proto-oncogenes. However, their exact ontogen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e1c7c6a6e73661102dbcefb4c5d147a
https://doi.org/10.1002/(sici)1096-9896(199803)184:3<247::aid-path994>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199803)184:3<247::aid-path994>3.0.co
Publikováno v:
The Journal of Pathology. 183:218-221
That carotid body tumours have a genetic aetiology is suggested by the familial occurrence of the neoplasm. Environmental influences are also implied by the fact that the tumour is more common in those living at high altitudes. However, the mechanism
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714c5f1ce93603a6c9c4cf30be16f0b8
https://doi.org/10.1002/(sici)1096-9896(199710)183:2<218::aid-path910>3.0.co
https://doi.org/10.1002/(sici)1096-9896(199710)183:2<218::aid-path910>3.0.co
Publikováno v:
Cancer. 80:668-675
BACKGROUND Neuroendocrine tumors of the gastroenteropancreatic system include pancreatic islet cell and carcinoid tumors. These tumors comprise a functionally and biologically heterogeneous group of neoplasms that rarely show reliable histopathologic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cde231f9d78569b83e243f4ad5dc6060
https://doi.org/10.1002/(sici)1097-0142(19970815)80:4<668::aid-cncr4>3.0.co
https://doi.org/10.1002/(sici)1097-0142(19970815)80:4<668::aid-cncr4>3.0.co
Publikováno v:
International Journal of Cancer. 74:270-274
pS2 protein expression has been demonstrated in a range of malignant tissues in an oestrogen-independent pathway. Recently, it has been demonstrated that pS2, in prostate cancer, is closely associated with neuro-endocrine differentiation. In the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::756a888663174819151191b67d0a3548
https://doi.org/10.1002/(sici)1097-0215(19970620)74:3<270::aid-ijc6>3.0.co
https://doi.org/10.1002/(sici)1097-0215(19970620)74:3<270::aid-ijc6>3.0.co
Publikováno v:
Cancer. 77:2581-2587
BACKGROUND. The genetic etiology of carotid body tumors is suggested by the familial occurrence of the neoplasm. Environmental influences are also implied by the fact that the tumor is more common in those living at high altitudes. However, the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::81bd39bf144043ef9ffb5fdf99f58c9b
https://doi.org/10.1002/(sici)1097-0142(19960615)77:12<2581::aid-cncr23>3.0.co
https://doi.org/10.1002/(sici)1097-0142(19960615)77:12<2581::aid-cncr23>3.0.co