Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Da-Eun Hwang"'
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152522 (2016)
Age-related macular degeneration (AMD) is the leading cause of vision loss and blindness among people over the age of 60. Vascular endothelial growth factor (VEGF) plays a major role in pathological angiogenesis in AMD. Herein, we present the develop
Externí odkaz:
https://doaj.org/article/84c34b9cada7461c91f50ba2df194ee5
Autor:
Gyehyun Lee, Seungjoon Kim, Da-Eun Hwang, Yu-Gon Eom, Gyubin Jang, Hye Yoon Park, Jeong-Mo Choi, Jaewon Ko, Yongdae Shin
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America; 3/19/2024, Vol. 121 Issue 12, p1-18, 30p
Autor:
Chan-Geun Kim, Da-Eun Hwang, Rajeev Kumar, Min Chung, Yu-Gon Eom, Hyunji Kim, Da-Hyun Koo, Jeong-Mo Choi
Publikováno v:
BMB Reports. 55:363-369
Autor:
Son Sumin, Yoonjoo Choi, Hyo-Deok Seo, Yoo-Kyoung Sohn, Joong-jae Lee, Da-Eun Hwang, Hak-Sung Kim
Publikováno v:
Biotechnology and Bioengineering. 117:1904-1908
Complement component 3a (C3a) plays a crucial role in the immune response and host defense, but it is also involved in pro-inflammatory responses, causing many inflammatory disorders. Blockade of C3a has been regarded as a potent therapeutic strategy
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 22, Iss 10736, p 10736 (2021)
International Journal of Molecular Sciences, Vol 22, Iss 10736, p 10736 (2021)
Biomolecular phase separation denotes the demixing of a specific set of intracellular components without membrane encapsulation. Recent studies have found that biomolecular phase separation is involved in a wide range of cellular processes. In partic
Autor:
Eun-Kyeong Jo, Hak-Sung Kim, Joong-jae Lee, Chul-Su Yang, Woosung Heu, Jung Min Choi, Da-Eun Hwang
Publikováno v:
Biochemical and Biophysical Research Communications. 477:1072-1077
The strongest anaphylatoxin, C5a, plays a critical role in the proinflammatory responses, causing the pathogenesis of a number of inflammatory diseases including sepsis, asthma, and rheumatoid arthritis. Inhibitors of C5a thus have great potential as
Autor:
Da-Eun Hwang, Yong-Keol Shin, Hak-Sung Kim, Palinda Ruvan Munashingha, Yeon-Soo Seo, So-Yeon Park
Publikováno v:
Biotechnology and Bioengineering. 113:2544-2552
A polymerase chain reaction (PCR) using a thermostable DNA polymerase is the most widely applied method in many areas of research, including life sciences, biotechnology, and medical sciences. However, a conventional PCR incurs an amplification of un
Autor:
Nury Kim, Jeong-Hyun Ryou, Woo Yong Park, Da-Eun Hwang, Miyoung Kim, Won Do Heo, Hak-Sung Kim, Yoo-Kyoung Sohn
Publikováno v:
Biotechnology and Bioengineering. 113:1639-1646
The intracellular delivery of proteins with high efficiency in a receptor-specific manner is of great significance in molecular medicine and biotechnology, but remains a challenge. Herein, we present the development of a highly efficient and receptor
Publikováno v:
Biochemical and Biophysical Research Communications. 464:1282-1289
The cell-specific cytosolic delivery of functional macromolecules with high efficiency is of great significance in molecular medicine and biotechnology. Herein, we present a Shiga-like toxin II-based high-efficiency and receptor-specific intracellula
Autor:
Hae-Kap Cheong, Yu Jung Kim, Hyun-Ho Kyeong, Seung-Goo Lee, Keunwan Park, Chul-Su Yang, Eun-Kyeong Jo, Dongsup Kim, Da Eun Hwang, Hak-Sung Kim, Jae-Min Yuk, Hyun Jung Kim, Jung Min Choi, Joong-jae Lee
Publikováno v:
Molecular Therapy. 22:1254-1265
Interleukin-6 (IL-6) is a multifunctional cytokine that regulates immune responses for host defense and tumorigenic process. Upregulation of IL-6 is known to constitutively phosphorylate signal transducer and activator of transcription 3 (STAT3), lea