Zobrazeno 1 - 10
of 202
pro vyhledávání: '"Da Zhong Xu"'
Autor:
Diego C Reino, Vadim Pisarenko, David Palange, Danielle Doucet, Robert P Bonitz, Qi Lu, Iriana Colorado, Sharvil U Sheth, Benjamin Chandler, Kolenkode B Kannan, Madhuri Ramanathan, Da Zhong Xu, Edwin A Deitch, Rena Feinman
Publikováno v:
PLoS ONE, Vol 6, Iss 8, p e14829 (2011)
BackgroundInjurious non-microbial factors released from the stressed gut during shocked states contribute to the development of acute lung injury (ALI) and multiple organ dysfunction syndrome (MODS). Since Toll-like receptors (TLR) act as sensors of
Externí odkaz:
https://doaj.org/article/14c935ccf42d4031b16d9051dee8602b
Autor:
Jiheng Xu, Lan Mo, Da-Zhong Xu, Minghao Zhong, Lei Xue, Xirui Guo, Minggang Peng, Xue-Ru Wu, Xuewei Zhao, Chuanshu Huang, Honglei Jin, Haishan Huang, Jingxia Li, Dongyun Zhang
Publikováno v:
Cell Adhesion & Migration, Vol 13, Iss 1, Pp 235-247 (2019)
Cell Adhesion & Migration
Cell Adhesion & Migration
Our previous studies have demonstrated that XIAP promotes bladder cancer metastasis through upregulating RhoGDIβ/MMP-2 pathway. However, the molecular mechanisms leading to the XIAP upregulation was unclear. In current studies, we found that XIAP wa
Publikováno v:
Toxicology and Applied Pharmacology. 340:30-38
Given the potential biological functions of spermatogonial stem cells (SSCs) in spermatogenesis and in delivering parental genetic information to the next generation, how these cells respond to environmental toxins and carcinogens should be investiga
Autor:
Danielle Doucet, Chirag Badami, David Palange, R Paul Bonitz, Qi Lu, Da-Zhong Xu, Kolenkode B Kannan, Iriana Colorado, Rena Feinman, Edwin A Deitch
Publikováno v:
PLoS ONE, Vol 5, Iss 2, p e9421 (2010)
Acute lung injury (ALI) and the development of the multiple organ dysfunction syndrome (MODS) is a major cause of death in trauma patients. Earlier studies in trauma hemorrhagic shock (T/HS) have documented that splanchnic ischemia leading to gut inf
Externí odkaz:
https://doaj.org/article/f4d080df77894a15be0efd7dfe77e2b3
Autor:
Vamsi Alli, Da-Zhong Xu, Gal Levy, Xiaofa Qin, Sharvil U. Sheth, Edwin A. Deitch, Yung Qin, Jordan E. Fishman, Qu Lu
Publikováno v:
Annals of Surgery. 260:1112-1120
To test whether the mucus layer, luminal digestive enzymes, and intestinal mast cells are critical components in the pathogenesis of trauma shock-induced gut and lung injury.Gut origin sepsis studies have highlighted the importance of the systemic co
Autor:
Lisa Gesumaria, Thomas Kluz, Da-Zhong Xu, Mary S. Matsui, Max Costa, Thomas L Des Marais, Xiaoru Zhang, Hong Sun
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-13 (2017)
Scientific Reports
Scientific Reports
Ultraviolet radiation (UVR) from sunlight is the major effector for skin aging and carcinogenesis. However, genes and pathways altered by solar-simulated UVR (ssUVR), a mixture of UVA and UVB, are not well characterized. Here we report global changes
Publikováno v:
Cell cycle (Georgetown, Tex.). 16(21)
The cellular hypoxic response contributes to cell transformation and tumor progression. Hypoxia-inducible factor 1 (HIF-1) is a key transcription factor that mediates transcription of genes whose products are essential for cellular adaptation to hypo
Autor:
Jiangwei Li, Weihua Huang, John T. Fallon, Xiaowen Zhang, Changhong Yin, Soyoung Park, Da-Zhong Xu, Cen Li
Gene 33 (Mig6, ERRFI1) is an adaptor protein with multiple cellular functions. We recently reported that depletion of this protein promotes lung epithelial cell transformation induced by hexavalent chromium [Cr(VI)]. However, the early molecular even
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8463b1dd60d90fcaa2004efe6ce72721
https://europepmc.org/articles/PMC5562372/
https://europepmc.org/articles/PMC5562372/
Autor:
Hong Zhao, Zbigniew Darzynkiewicz, Leonard M. Eisenberg, Xiaowen Zhang, Da-Zhong Xu, Cen Li, So-Young Park
Publikováno v:
The Journal of biological chemistry. 292(40)
Gene 33 (Mig6, ERRFI1) is an adaptor protein with multiple cellular functions. We recently linked Gene 33 to the DNA damage response (DDR) induced by hexavalent chromium (Cr(VI)), but the molecular mechanism remains unknown. Here we show that ectopic
Autor:
Hsiang-Chi Tseng, Max Costa, Magdy Shamy, Da-Zhong Xu, Kathrin Kiok, Hong Sun, Jason Brocato, Lei Fang, Danqi Chen, Chunyuan Jin, Yana Chervona
Publikováno v:
Journal of Biological Chemistry. 289:31751-31764
The replication-dependent histone genes are the only metazoan genes whose messenger RNA (mRNA) does not terminate with a poly(A) tail at the 3'-end. Instead, the histone mRNAs display a stem-loop structure at their 3'-end. Stem-loop-binding protein (