Zobrazeno 1 - 10
of 939
pro vyhledávání: '"Da Spandidos"'
Autor:
JK Field, H Kiaris, JM Risk, C Tsiriyotis, R Adamson, V Zoumpourlis, H Rowley, K Taylor, J Whittaker, P Howard, JC Beirne, JR Gosney, J Woolgar, ED Vaughan, DA Spandidos, AS Jones
Publikováno v:
British Journal of Cancer
Allelic imbalance or loss of heterozygosity (LOH) studies have been used extensively to identify regions on chromosomes that may contain putative tumour-suppressor genes. We have undertaken an extensive allelotype of 80 specimens of squamous cell car
Publikováno v:
Europe PubMed Central
ras genes are thought to play an important role in human cancer since they have been found to be activated frequently in several types of human tumors. From preliminary studies it has been found however, that ras mutations are extremely rare in breas
Autor:
M. Ergazaki, Athina Giannoudis, N Markomichelakis, J. Tsamparlakis, Da Spandidos, George Xinarianos
Publikováno v:
Europe PubMed Central
Herpes simplex virus (HSV), cytomegalovirus (CMV) and Epstein-Barr virus (EBV) have been recognized as pathogenic agents of intraocular inflammatory conditions. The ability of the Polymerase Chain Reaction (PCR) technique to amplify HSV, CMV and EBV
Autor:
M. Ergazaki, C. Kattamis, Maria Koffa, Triantafillos Liloglou, Da Spandidos, Athina Giannoudis, George Xinarianos
Publikováno v:
Europe PubMed Central
Infections caused by Human Cytomegalovirus (HCMV) and Epstein-Barr virus (EBV) are common in multiple transfused patients, such as patients with beta-thalassaemia. The ability of the Polymerase Chain Reaction (PCR) to amplify HCMV and EBV DNA from bl
Publikováno v:
Oncology Reports 1:1(Jan-Feb1994):107-110
Europe PubMed Central
Europe PubMed Central
Journal URL: http://www.spandidos.com/or/ It is now widely accepted that human neoplasms arise as a result of a sequence of mutations affecting the structure of genes involved in growth control. Identifying the nature of such genetic mutations in thy
Publikováno v:
Europe PubMed Central
Investigation of the nucleotide sequence of the HIV-1 LTR showed the presence of four novel short DNA regions which are homologous to the recognition site for the cellular transcription factor AP-1. Four short oligonucleotide hybrids containing these
Publikováno v:
Europe PubMed Central
Oncology Reports 2:5(Sep-Oct1995):769-771
Oncology Reports 2:5(Sep-Oct1995):769-771
Mutations in the ras family genes (K-ras mainly) represent a common event in lung tumorigenesis which is frequently associated with poor clinical outcome. In order to investigate whether K-ras mutations are detectable in cytological material obtained
Publikováno v:
Europe PubMed Central
Bladder cancers are usually curable, by surgical or transurethral excision, if diagnosed at an early stage. Tumor derived mutations in oncogenes potentially provide specific markers for the detection of surgically resectable tumors. The detection of
Publikováno v:
Europe PubMed Central
We describe a PCR based method for qualitative and quantitative analysis of the H-ras gene. For qualitative analysis the aim was to detect codon 12 point mutations at transcriptional and genomic levels by a non-radioactive RFLP assay. Quantitative an
Publikováno v:
Europe PubMed Central
There is evidence that hormone regulation of cellular oncogenes plays an essential role in human cancer. The c-H-ras gene is implicated through both mutation and abnormal gene expression in many types of human cancer. Computer scanning of this gene h