Everolimus for cardiac rhabdomyomas in children with tuberous sclerosis. The ORACLE study protocol (everOlimus for caRdiac rhAbdomyomas in tuberous sCLErosis): a randomised, multicentre, placebo-controlled, double-blind phase II trial.

Autor: Stelmaszewski EV; Pediatric Cardiology Department, Hospital de Pediatría Garrahan, Buenos Aires, Argentina., Parente DB; Radiology Department, D'Or Institute for Research and Education, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Farina A; Medical Affairs Department, Mundipharma Pharmaceuticals SRL, Milan, Italy., Stein A; Nephrology Department, Hospital Moinhos de Vento, Porto Alegre, Brazil., Gutierrez A; Medical Department, Pontificia Universidad Católica Madre y Maestra, Facultad Ciencias de la Salud, Santiago de los Caballeros, Dominican Republic., Raquelo-Menegassio AF; Medical Department, Escola Bahiana de Medicina e Saúde Pública, Salvador, Bahía, Brazil., Manterola C; Neurology Department, Clínica Alemana de Santiago/Facultad de Medicina, Universidad de Chile, Santiago, Chile., de Sousa CF; Pharmacy Department, Faculdades Oswaldo Cruz, São Paulo, Brazil., Victor C; Oncology Department, Instituto do Cáncer do Estado de São Paulo (ICESP), São Paulo, Brazil., Maki D; Nephrology Department, Hamad General Hospital, Hamad Medical Corporation (HMC), Doha, Qatar., Morón EM; Adjunct Faculty, Community and Public Health Sciences Department, Nova Southeastern University College of Dental Medicine, Davie, FL, USA.; Community Dentistry and Behavioral Science Department, University of Florida College of Dentistry, Gainesville, FL, USA., de Abrantes FF; Neurology Department, Universidade Federal da São Paulo (UNIFESP), São Paulo, Brazil., Iqbal F; Infectious Diseases Department, Communicable Disease Center, Doha, Qatar., Camacho-Vilchez J; Oncology Department, Instituto Nacional del Cancer 'Rosa Emilia Sanchez Perez de Tavares' C/Correa y Cidrón, Ciudad Universitaria, Santo Domingo, Dominican Republic., Jimenez-Pavón J; Mood Disorders Department, National Institute of Psychiatry, México City, México., Polania JP; Pediatric Neurology Department, Hospital Pediatrico la Misericordia, Bogotá, Colombia., Thompson L; Medical Department, Universidad Iberoamericana Unibe, Santo Domingo, Dominican Republic., Bonanato L; Medical Department, Eurofarma, São Paulo, Brazil., Diebold M; Nephrology Department, Cardiovascular Research Institute, Basel, Switzerland., Da Silva MVCP; Ophthalmology Department, Princess Margaret Cancer Center, University of Toronto, Toronto, Ontario, Canada., Nashwan MWJ; Medical Department, University of Jordan, Amman, Jordan.; Emergency Department, Hamad Medical Corporation, Doha, Qatar., Galvani MAG; Oncology Department, Faculdade de Medicina do ABC, Santo André, Brazil., Idris OEA; Geriatric Department, Hamad General Hospital, Hamad Medical Corporation, Doha, Qatar., Danos P; Genetics and Molecular Biology Department, Centro de Genética y Biología Molecular (CGBM), Instituto de Investigación - Facultad de Medicina Humana, Universidad de San Martín de Porres (USMP), La Molina, Lima, Perú., Ortiz-Lopez R; Medical Department, Escuela de Medicina y Ciencias de la Salud, Tecnologico de Monterrey, Monterrey, Mexico., Mahmoud RAA; Pharmacy Department, Hamad Medical Corporation, Doha, Qatar., Gresse S; Health Economics and Outcomes Research Department, Baxter Healthcare, São Paulo, Brazil., Loss KL; Pediatric Cardiology Department, Dr Alzir Bernardino Alves Pediatric Hospital and Maternity, Vila Velha, Espírito Santo, Brazil.

Publikováno v: Cardiology in the young [Cardiol Young] 2020 Mar; Vol. 30 (3), pp. 337-345. Date of Electronic Publication: 2020 Jan 27.