Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Da Silva Couto Alves, Alexessander"'
Autor:
Da Silva Couto Alves, Alexessander, De Silva, N. Maneka G., Karhunen, Ville, Sovio, Ulla, Das, Shikta, Taal, H. Rob, Warrington, Nicole M., Lewin, Alexandra M., Kaakinen, Marika, Cousminer, Diana L., Thiering, Elisabeth, Timpson, Nicholas J., Bond, Tom A., Lowry, Estelle, Brown, Christopher D., Estivill, Xavier, Lindi, Virpi, Bradfield, Jonathan P., Geller, Frank, Speed, Doug, Coin, Lachlan J. M., Loh, Marie, Barton, Sheila J., Beilin, Lawrence J., Bisgaard, Hans, Bonnelykke, Klaus, Alili, Rohia, Hatoum, Ida J., Schramm, Katharina, Cartwright, Rufus, Charles, Marie-Aline, Salerno, Vincenzo, Clement, Karine, Claringbould, Annique A.J, Consortium, BIOS, van Duijin, Cornelia M., Moltchanova, Elena, Eriksson, Johan G., Elks, Cathy, Feenstra, Bjarke, Flexeder, Claudia, Franks, Stephen, Frayling, Timothy M., Freathy, Rachel M., Elliot, Paul, Widen, Elisabeth, Hakonarson, Hakon, Hattersley, Andrew T., Rodriguez, Alina, Banterle, Marco, Heinrich, Joachim, Heude, Barbara, Holloway, John W., Hofman, Albert, Hypponen, Elina, Inskip, Hazel, Kaplan, Lee M., Hedman, Asa K., Laara, Esa, Prokisch, Holger, Grallert, Harald, Lakka, Timo A., Lawlor, Debbie A., Melbye, Mads, Ahluwalia, Tarunveer S., Marinelli, Marcella, Millwood, Iona Y., Palmer, Lyle J., Pennell, Craig E., Perry, John R., Ring, Susan M., Savolainen, Markku J., Rivadeneira, Fernando, Standl, Marie, Sunyer, Jordi, Tiesler, Carla M.T, Uitterlinden, Andre G., Schierding, William, O'Sullivan, Justin M., Prokopenko, Inga, Herzig, Karl-Heinz, Smith, George Davey, O'Reilly, Paul, Felix, Janine F., Buxton, Jessica L., Blakemore, Alexandra L. F, Ong, Ken K., Jaddoe, Vincent W.V, Grant, Struan F.A, Sebert, Sylvain, McCarthy, Mark L., Jarvelin, Marjo-Riitta
Early childhood growth patterns are associated with adult health, yet the genetic factors and the developmental stages involved are not fully understood. Here, we combine genome-wide association studies with modeling of longitudinal growth traits to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______305::8de8cd9bbdebfef37d3df5d4393ff4c4
https://surrey.eprints-hosting.org/853928/
https://surrey.eprints-hosting.org/853928/
Autor:
Demenais, Florence, Margaritte-Jeannin, Patricia, Barnes, Kathleen C, Cookson, William O. C. M., Altmüller, Janine, Ang, Wei, Barr, R Graham, Beaty, Terri H, Becker, Allan B, Beilby, John, Bisgaard, Hans, Bjornsdottir, Unnur Steina, Bleecker, Eugene, Bønnelykke, Klaus, Boomsma, Dorret I, Bouzigon, Emmanuelle, Brightling, Christopher E, Brossard, Myriam, Brusselle, Guy G, Burchard, Esteban G., Burkart, Kristin M, Bush, Andrew, Chan-Yeung, Moira, Chung, Kian Fan, Da Silva Couto Alves, Alexessander, Curtin, John A, Custovic, Adnan, Daley, Denise, de Jongste, Johan C, Del-Rio-Navarro, Blanca E, Donohue, Kathleen M, Duijts, Liesbeth, Eng, Celeste, Eriksson, Johan G, Farrall, Martin, Fedorova, Yuliya, Feenstra, Bjarke, Ferreira, Manuel A, Freidin, Maxim B., Gajdos, Zofia, Gauderman, Jim, Gehring, Ulrike, Geller, Frank, Genuneit, Jon, Gharib, Sina A, Gilliland, Frank, Granell, Raquel, Graves, Penelope E, Heederik, Dick, Wouters, Inge M, Australian Asthma Genetics Consortium (AAGC) collaborators
We examined common variation in asthma risk by conducting a meta-analysis of worldwide asthma genome-wide association studies (23,948 asthma cases, 118,538 controls) of individuals from ethnically diverse populations. We identified five new asthma lo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_______101::0644ff4aac7646764a38b2c0996b4c4a
https://dspace.library.uu.nl/handle/1874/375260
https://dspace.library.uu.nl/handle/1874/375260
Autor:
Boritza, Kátia Cristina, dos Santos-Weiss, Izabella Castilhos Ribeiro, da Silva Couto Alves, Alexessander, Réa, Rosângela Roginski, Pedrosa, Fábio Oliveira, de Souza, Emanuel Maltempi, Picheth, Geraldo, de Moraes Rego, Fabiane Gomes
Publikováno v:
Clinical Chemistry & Laboratory Medicine; Aug2014, Vol. 52 Issue 8, pe179-e181, 3p
Autor:
Li, Chen, Stoma, Svetlana, Lotta, Luca A, Warner, Sophie, Albrecht, Eva, Allione, Alessandra, Arp, Pascal P, Broer, Linda, Buxton, Jessica L, Da Silva Couto Alves, Alexessander, Deelen, Joris, Fedko, Iryna O, Gordon, Scott D, Jiang, Tao, Karlsson, Robert, Kerrison, Nicola, Loe, Taylor K, Mangino, Massimo, Milaneschi, Yuri, Miraglio, Benjamin, Pervjakova, Natalia, Russo, Alessia, Surakka, Ida, Van Der Spek, Ashley, Verhoeven, Josine E, Amin, Najaf, Beekman, Marian, Blakemore, Alexandra I, Canzian, Federico, Hamby, Stephen E, Hottenga, Jouke-Jan, Jones, Peter D, Jousilahti, Pekka, Mägi, Reedik, Medland, Sarah E, Montgomery, Grant W, Nyholt, Dale R, Perola, Markus, Pietiläinen, Kirsi H, Salomaa, Veikko, Sillanpää, Elina, Suchiman, H Eka, Van Heemst, Diana, Willemsen, Gonneke, Agudo, Antonio, Boeing, Heiner, Boomsma, Dorret I, Chirlaque, Maria-Dolores, Fagherazzi, Guy, Ferrari, Pietro, Franks, Paul, Gieger, Christian, Eriksson, Johan Gunnar, Gunter, Marc, Hägg, Sara, Hovatta, Iiris, Imaz, Liher, Kaprio, Jaakko, Kaaks, Rudolf, Key, Timothy, Krogh, Vittorio, Martin, Nicholas G, Melander, Olle, Metspalu, Andres, Moreno, Concha, Onland-Moret, N Charlotte, Nilsson, Peter, Ong, Ken K, Overvad, Kim, Palli, Domenico, Panico, Salvatore, Pedersen, Nancy L, Penninx, Brenda WJH, Quirós, J Ramón, Jarvelin, Marjo Riitta, Rodríguez-Barranco, Miguel, Scott, Robert A, Severi, Gianluca, Slagboom, P Eline, Spector, Tim D, Tjonneland, Anne, Trichopoulou, Antonia, Tumino, Rosario, Uitterlinden, André G, Van Der Schouw, Yvonne T, Van Duijn, Cornelia M, Weiderpass, Elisabete, Denchi, Eros Lazzerini, Matullo, Giuseppe, Butterworth, Adam S, Danesh, John, Samani, Nilesh J, Wareham, Nicholas J, Nelson, Christopher P, Langenberg, Claudia, Codd, Veryan
Leukocyte telomere length (LTL) is a heritable biomarker of genomic aging. In this study, we perform a genome-wide meta-analysis of LTL by pooling densely genotyped and imputed association results across large-scale European-descent studies including
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e783ba2a4ba14273e6a1175897bcc7a3
Genome-wide Association Analysis in Humans Links Nucleotide Metabolism to Leukocyte Telomere Length.
Autor:
Li, Chen1,2 (AUTHOR), Stoma, Svetlana1,2,3 (AUTHOR), Lotta, Luca A.1 (AUTHOR), Warner, Sophie1,3 (AUTHOR), Albrecht, Eva4 (AUTHOR), Allione, Alessandra5,6 (AUTHOR), Arp, Pascal P.7 (AUTHOR), Broer, Linda7 (AUTHOR), Buxton, Jessica L.8,9 (AUTHOR), Da Silva Couto Alves, Alexessander10,11 (AUTHOR), Deelen, Joris12,13 (AUTHOR), Fedko, Iryna O.14 (AUTHOR), Gordon, Scott D.15 (AUTHOR), Jiang, Tao16 (AUTHOR), Karlsson, Robert17 (AUTHOR), Kerrison, Nicola1 (AUTHOR), Loe, Taylor K.18 (AUTHOR), Mangino, Massimo19,20 (AUTHOR), Milaneschi, Yuri21 (AUTHOR), Miraglio, Benjamin22 (AUTHOR)
Publikováno v:
American Journal of Human Genetics. Mar2020, Vol. 106 Issue 3, p389-404. 16p.
Autor:
Kato N; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Loh M; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Translational Laboratory in Genetic Medicine, Agency for Science, Technology and Research (ASTAR), Singapore., Takeuchi F; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Verweij N; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wang X; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Zhang W; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Kelly TN; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA., Saleheen D; Center for Non-Communicable Diseases, Karachi, Pakistan.; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.; Cardiovascular Institute, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, Pennsylvania, USA., Lehne B; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Leach IM; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Drong AW; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK., Abbott J; Bioinformatics Support Service, Imperial College London, London, UK., Wahl S; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Diabetes Research (DZD), Neuherberg, Germany., Tan ST; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Scott WR; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Campanella G; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Chadeau-Hyam M; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Afzal U; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Ahluwalia TS; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; Copenhagen Prospective Studies on Asthma in Childhood (COSPAC), Herlev and Gentofte Hospital, University of Copenhagen, Copenhagen, Denmark.; Steno Diabetes Center, Gentofte, Denmark., Bonder MJ; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Chen P; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Dehghan A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Edwards TL; Vanderbilt Epidemiology Center, Center for Human Genetics Research, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Esko T; Estonian Genome Center, University of Tartu, Tartu, Estonia.; Division of Endocrinology, Children's Hospital Boston, Boston, Massachusetts, USA.; Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA.; Program in Medical and Population Genetics, Broad Institute, Cambridge, Massachusetts, USA., Go MJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Harris SE; Medical Genetics Section, University of Edinburgh Centre for Genomic and Experimental Medicine and Medical Research Council (MRC) Institute of Genetics and Molecular Medicine, Western General Hospital, Edinburgh, UK.; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK., Hartiala J; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.; Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA., Kasela S; Estonian Genome Center, University of Tartu, Tartu, Estonia., Kasturiratne A; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Khor CC; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Department of Paediatrics, National University of Singapore, Singapore., Kleber ME; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Li H; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Yu Mok Z; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Nakatochi M; Center for Advanced Medicine and Clinical Research, Nagoya University Hospital, Nagoya, Japan., Sapari NS; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Saxena R; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Stewart AFR; University of Ottawa Heart Institute, Cardiovascular Research Methods Centre, Ottawa, Ontario, Canada.; Ruddy Canadian Cardiovascular Genetics Centre, Ottawa, Ontario, Canada., Stolk L; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Tabara Y; Center for Genomic Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan., Teh AL; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore., Wu Y; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Wu JY; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Zhang Y; State Key Laboratory of Medical Genetics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Hypertension, Shanghai, China., Aits I; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany., Da Silva Couto Alves A; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Das S; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK., Dorajoo R; Genome Institute of Singapore, ASTAR, Singapore., Hopewell JC; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Kim YK; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Koivula RW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden., Luan J; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Nguyen QN; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Pereira MA; School of Public Health, University of Minnesota, Minneapolis, Minnesota, USA., Postmus I; Department of Gerontology and Geriatrics, Leiden University Medical Center, Leiden, the Netherlands.; Netherlands Consortium for Healthy Ageing, Leiden, the Netherlands., Raitakari OT; Department of Clinical Physiology and Nuclear Medicine, Turku University Hospital, Turku, Finland.; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Turku, Turku, Finland., Scannell Bryan M; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Scott RA; MRC Epidemiology Unit, Institute of Metabolic Science, University of Cambridge, Cambridge, UK., Sorice R; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Tragante V; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Traglia M; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.; Institute for Maternal and Child Health, Istituto di Ricovero e Cura a Carattere Scientifico (IRCCS) 'Burlo Garofolo', Trieste, Italy., White J; University College London Genetics Institute, Department of Genetics, Environment and Evolution, University College London, London, UK., Yamamoto K; Division of Genomics, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan., Zhang Y; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Adair LS; Department of Nutrition, University of North Carolina, Chapel Hill, North Carolina, USA., Ahmed A; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh., Akiyama K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Asif R; Center for Non-Communicable Diseases, Karachi, Pakistan., Aung T; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Barroso I; Metabolic Disease Group, Wellcome Trust Sanger Institute, Cambridge, UK.; National Institute for Health Research (NIHR) Cambridge Biomedical Research Centre, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK.; University of Cambridge Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke's Hospital, Cambridge, UK., Bjonnes A; Center for Human Genetic Research, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Braun TR; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Cai H; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Chang LC; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Chen CH; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan.; School of Chinese Medicine, China Medical University, Taichung, Taiwan., Cheng CY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Centre for Quantitative Medicine, Office of Clinical Sciences, Duke-National University of Singapore Graduate Medical School, Singapore., Chong YS; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Collins R; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Courtney R; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Davies G; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Delgado G; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Do LD; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Doevendans PA; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands., Gansevoort RT; Department of Internal Medicine, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Gao YT; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Grammer TB; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany., Grarup N; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Grewal J; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Gu D; Fu Wai Hospital and Cardiovascular Institute, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China., Wander GS; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India., Hartikainen AL; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., Hazen SL; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cell Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., He J; Department of Biostatistics, Vanderbilt University, Nashville, Tennessee, USA., Heng CK; Department of Paediatrics, Yong Loo Lin School of Medicine, Singapore., Hixson JE; Human Genetics Center, University of Texas School of Public Health at Houston, Houston, Texas, USA., Hofman A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Hsu C; University of Southern California Keck School of Medicine, Los Angeles, California, USA., Huang W; Department of Genetics, Chinese National Human Genomic Center, Shanghai, China., Husemoen LLN; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark., Hwang JY; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Ichihara S; Graduate School of Regional Innovation Studies, Mie University, Tsu, Japan., Igase M; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan., Isono M; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Justesen JM; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Katsuya T; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Kibriya MG; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Kim YJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Kishimoto M; National Center for Global Health and Medicine, Toyama, Japan., Koh WP; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Duke-National University of Singapore Graduate Medical School, Singapore., Kohara K; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan., Kumari M; Department of Epidemiology and Public Health, University College London, London, UK., Kwek K; K.K. Women's and Children's Hospital, Singapore., Lee NR; University of San Carlos Office of Population Studies Foundation, University of San Carlos, Cebu City, Philippines.; Department of Anthropology, Sociology and History, University of San Carlos, Cebu City, Philippines., Lee J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., Liao J; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Lieb W; Institute of Epidemiology and Biobank popgen, Christian Albrechts University of Kiel, Kiel, Germany., Liewald DCM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Matsubara T; Department of Internal Medicine, Aichi-Gakuin University School of Dentistry, Nagoya, Japan., Matsushita Y; National Center for Global Health and Medicine, Toyama, Japan., Meitinger T; Institute of Human Genetics, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Human Genetics, Technische Universität München, Munich, Germany., Mihailov E; Estonian Genome Center, University of Tartu, Tartu, Estonia., Milani L; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mills R; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK., Mononen N; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Müller-Nurasyid M; Institute of Genetic Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Department of Medicine I, Ludwig Maximilians University Munich, Munich, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Nabika T; Department of Functional Pathology, Shimane University Faculty of Medicine, Izumo, Japan., Nakashima E; Division of Endocrinology and Diabetes, Department of Internal Medicine, Nagoya University Graduate School of Medicine, Nagoya, Japan.; Department of Diabetes and Endocrinology, Chubu Rosai Hospital, Nagoya, Japan., Ng HK; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Nikus K; Heart Centre, Department of Cardiology, Tampere University Hospital and University of Tampere School of Medicine, Tampere, Finland., Nutile T; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Ohkubo T; Department of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan., Ohnaka K; Department of Geriatric Medicine, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan., Parish S; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Paternoster L; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK., Peng H; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Peters A; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; German Center for Cardiovascular Research (DZHK), partner site Munich Heart Alliance, Munich, Germany., Pham ST; Vietnam National Heart Institute, Bach Mai Hospital, Hanoi, Vietnam., Pinidiyapathirage MJ; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Rahman M; UChicago Research Bangladesh, Uttara, Dhaka, Bangladesh.; Research and Evaluation Division, Bangladesh Rehabilitation Assistance Committee (BRAC), Dhaka, Bangladesh., Rakugi H; Department of Geriatric Medicine and Nephrology, Osaka University Graduate School of Medicine, Suita, Japan., Rolandsson O; Department of Public Health and Clinical Medicine, Section for Family Medicine, Umeå Universitet, Umeå, Sweden., Ann Rozario M; Cancer Science Institute of Singapore, National University of Singapore, Singapore., Ruggiero D; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Sala CF; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy., Sarju R; Dayanand Medical College and Hospital Unit, Hero DMC Heart Institute, Ludhiana, India., Shimokawa K; Department of Gene Diagnostics and Therapeutics, Research Institute, National Center for Global Health and Medicine, Tokyo, Japan., Snieder H; Department of Epidemiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Sparsø T; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Spiering W; Department of Vascular Medicine, University Medical Center Utrecht, Utrecht, the Netherlands., Starr JM; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Alzheimer Scotland Dementia Research Centre, University of Edinburgh, Edinburgh, UK., Stott DJ; Academic Section of Geriatric Medicine, Institute of Cardiovascular and Medical Sciences, Faculty of Medicine, University of Glasgow, Glasgow, UK., Stram DO; University of Southern California Keck School of Medicine, Los Angeles, California, USA., Sugiyama T; Institute for Adult Diseases, Asahi Life Foundation, Tokyo, Japan., Szymczak S; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Tang WHW; Department of Cardiovascular Medicine, Heart and Vascular Institute, Cleveland Clinic, Cleveland, Ohio, USA.; Department of Cellular and Molecular Medicine, Lerner Research Institute, Cleveland Clinic, Cleveland, Ohio, USA., Tong L; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Trompet S; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Turjanmaa V; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland., Ueshima H; Department of Health Science, Shiga University of Medical Science, Otsu, Japan.; Center for Epidemiologic Research in Asia, Shiga University of Medical Science, Otsu, Japan., Uitterlinden AG; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands.; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Umemura S; Department of Medical Science and Cardiorenal Medicine, Yokohama City University Graduate School of Medicine, Yokohama, Japan., Vaarasmaki M; Department of Obstetrics and Gynecology, Oulu University Hospital, Oulu, Finland.; Medical Research Center, University of Oulu, Oulu, Finland.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland., van Dam RM; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore., van Gilst WH; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., van Veldhuisen DJ; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Viikari JS; Division of Medicine, Turku University Hospital, Turku, Finland.; Department of Medicine, University of Turku, Turku, Finland., Waldenberger M; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wang Y; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Wang A; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Wilson R; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Wong TY; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore., Xiang YB; Department of Epidemiology, Shanghai Cancer Institute, Shanghai, China., Yamaguchi S; Third Department of Internal Medicine, Shimane University Faculty of Medicine, Izumo, Japan., Ye X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Young RD; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK., Young TL; Neuroscience and Behavioural Disorders (NBD) Program, Duke-National University of Singapore Graduate Medical School, Singapore.; Duke Eye Center, Duke University Medical Center, Durham, North Carolina, USA., Yuan JM; Cancer Control and Population Sciences, University of Pittsburgh Cancer Institute, Pittsburgh, Pennsylvania, USA., Zhou X; Bioinformatics Division, Tsinghua National Laboratory for Informatics Science and Technology (TNLIST), Ministry of Education Key Laboratory of Bioinformatics, Department of Automation, Tsinghua University, Beijing, China.; Center for Synthetic and Systems Biology, TNLIST, Ministry of Education Key Laboratory of Bioinformatics, Department of Automation, Tsinghua University, Beijing, China.; Department of Psychiatry, University of Hong Kong, Hong Kong., Asselbergs FW; Division of Heart and Lungs, Department of Cardiology, University Medical Center Utrecht, Utrecht, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands.; Institute of Cardiovascular Science, Faculty of Population Health Sciences, University College London, London, UK., Ciullo M; Institute of Genetics and Biophysics A Buzzati-Traverso, CNR, Naples, Italy., Clarke R; Clinical Trials Support Unit (CTSU), Nuffield Department of Population Health, University of Oxford, Oxford, UK., Deloukas P; William Harvey Research Institute, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, London, UK.; King Abdulaziz University, Jeddah, Saudi Arabia., Franke A; Institute of Clinical Molecular Biology, Christian Albrechts University of Kiel, Kiel, Germany., Franks PW; Department of Clinical Sciences, Genetic and Molecular Epidemiology Unit, Skåne University Hospital Malmö, Malmö, Sweden.; Department of Public Health and Clinical Medicine, Section for Family Medicine, Umeå Universitet, Umeå, Sweden.; Department of Nutrition, Harvard School of Public Health, Boston, Massachusetts, USA., Franks S; Institute of Reproductive and Developmental Biology, Imperial College London, Hammersmith Hospital, London, UK., Friedlander Y; Hebrew University, School of Public Health, Jerusalem, Israel., Gross MD; School of Medicine, University of Minnesota, Minneapolis, Minnesota, USA., Guo Z; Department of Epidemiology, School of Public Health, Medical College of Soochow University, Suzhou, China., Hansen T; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Jarvelin MR; Institute of Health Sciences, University of Oulu, Oulu, Finland.; Department of Epidemiology and Biostatistics, MRC Health Protection Agency (PHE) Centre for Environment and Health, School of Public Health, Imperial College London, London, UK.; Unit of Primary Care, Oulu University Hospital, Oulu, Finland.; Biocenter Oulu, University of Oulu, Oulu, Finland.; Center for Life Course Epidemiology, Faculty of Medicine, University of Oulu, Oulu, Finland., Jørgensen T; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark., Jukema JW; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands.; ICIN, Utrecht, the Netherlands., Kähönen M; Department of Clinical Physiology, Tampere University Hospital, Tampere, Finland.; Department of Clinical Physiology, University of Tampere School of Medicine, Tampere, Finland., Kajio H; National Center for Global Health and Medicine, Toyama, Japan., Kivimaki M; Department of Epidemiology and Public Health, University College London, London, UK., Lee JY; Ministry of Health and Welfare, Seoul, Republic of Korea.; THERAGEN ETEX Bio Institute, Suwon, Republic of Korea., Lehtimäki T; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland.; Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Linneberg A; Research Centre for Prevention and Health, Glostrup University Hospital, Glostrup, Denmark.; Department of Clinical Experimental Research, Rigshospitalet, Copenhagen, Denmark.; Department of Clinical Medicine, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Miki T; Department of Geriatric Medicine, Ehime University Graduate School of Medicine, Toon, Ehime, Japan., Pedersen O; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark., Samani NJ; Department of Cardiovascular Sciences, University of Leicester, Glenfield Hospital, Leicester, UK.; NIHR Leicester Cardiovascular Biomedical Research Unit, Glenfield Hospital, Leicester, UK., Sørensen TIA; Novo Nordisk Foundation Centre for Basic Metabolic Research, Section of Metabolic Genetics, Faculty of Health and Medical Sciences, University of Copenhagen, Copenhagen, Denmark.; MRC Integrative Epidemiology Unit, University of Bristol, Bristol, UK.; Institute of Preventive Medicine, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark., Takayanagi R; Department of Medicine and Bioregulatory Science, Graduate School of Medical Sciences, Kyushu University, Kyushu, Japan., Toniolo D; Division of Genetics and Cell Biology, San Raffaele Scientific Institute, Milan, Italy.; Institute of Molecular Genetics, National Research Council (CNR), Pavia, Italy., Ahsan H; Department of Public Health Sciences, University of Chicago, Chicago, Illinois, USA., Allayee H; Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA.; Institute for Genetic Medicine, University of Southern California Keck School of Medicine, Los Angeles, California, USA., Chen YT; Institute of Biomedical Sciences, Academia Sinica, Taipei, Taiwan., Danesh J; Department of Public Health and Primary Care, University of Cambridge, Strangeways Research Laboratory, Cambridge, UK.; Wellcome Trust Sanger Institute, Hinxton, UK., Deary IJ; Centre for Cognitive Aging and Cognitive Epidemiology, University of Edinburgh, Edinburgh, UK.; Department of Psychology, University of Edinburgh, Edinburgh, UK., Franco OH; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Franke L; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Heijman BT; Molecular Epidemiology, Leiden University Medical Center, Leiden, the Netherlands., Holbrook JD; Singapore Institute for Clinical Sciences (SICS), ASTAR, Singapore., Isaacs A; Department of Epidemiology, Erasmus University Medical Center, Rotterdam, the Netherlands., Kim BJ; Center for Genome Science, National Institute of Health, Osong Health Technology Administration Complex, Chungcheongbuk-do, Republic of Korea., Lin X; Key Laboratory of Nutrition and Metabolism, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai, China., Liu J; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore., März W; Medical Clinic V, Mannheim Medical Faculty, University of Heidelberg, Mannheim, Germany.; Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Graz, Graz, Austria.; Synlab Academy, Synlab Services, Mannheim, Germany., Metspalu A; Estonian Genome Center, University of Tartu, Tartu, Estonia., Mohlke KL; Department of Genetics, University of North Carolina, Chapel Hill, North Carolina, USA., Sanghera DK; Department of Pediatrics, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, USA., Shu XO; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., van Meurs JBJ; Department of Internal Medicine, Erasmus University Medical Center, Rotterdam, the Netherlands., Vithana E; Department of Ophthalmology, National University of Singapore, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; Neuroscience and Behavioural Disorders (NBD) Program, Duke-National University of Singapore Graduate Medical School, Singapore., Wickremasinghe AR; Department of Public Health, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka., Wijmenga C; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Wolffenbuttel BHW; Department of Endocrinology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands., Yokota M; Department of Genome Science, Aichi-Gakuin University School of Dentistry, Nagoya, Japan., Zheng W; Vanderbilt Epidemiology Center, Division of Epidemiology, Department of Medicine, Vanderbilt Genetics Institute, Vanderbilt University, Nashville, Tennessee, USA.; Vanderbilt-Ingram Cancer Center, Division of Epidemiology, Department of Medicine, Vanderbilt University, Nashville, Tennessee, USA., Zhu D; State Key Laboratory of Medical Genetics, Shanghai Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.; Shanghai Institute of Hypertension, Shanghai, China., Vineis P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Kyrtopoulos SA; National Hellenic Research Foundation, Institute of Biology, Medicinal Chemistry and Biotechnology, Athens, Greece., Kleinjans JCS; Department of Toxicogenomics, Maastricht University, Maastricht, the Netherlands., McCarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK.; Oxford Centre for Diabetes Endocrinology and Metabolism, University of Oxford, Oxford, UK., Soong R; Cancer Science Institute of Singapore, National University of Singapore, Singapore.; Department of Pathology, National University of Singapore, Singapore., Gieger C; Research Unit of Molecular Epidemiology, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany.; Institute of Epidemiology II, Helmholtz Zentrum München-German Research Center for Environmental Health, Neuherberg, Germany., Scott J; National Heart and Lung Institute, Imperial College London, London, UK., Teo YY; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Genome Institute of Singapore, ASTAR, Singapore.; Singapore Eye Research Institute, Singapore National Eye Centre, Singapore.; National University of Singapore Graduate School for Integrative Science and Engineering, National University of Singapore, Singapore.; Life Sciences Institute, National University of Singapore, Singapore.; Department of Statistics and Applied Probability, National University of Singapore, Singapore., He J; Department of Epidemiology, Tulane University School of Public Health and Tropical Medicine, New Orleans, Louisiana, USA., Elliott P; Department of Epidemiology and Biostatistics, Imperial College London, London, UK., Tai ES; Saw Swee Hock School of Public Health, National University of Singapore and National University Health System, Singapore.; Department of Clinical Gene Therapy, Osaka University Graduate School of Medicine, Suita, Japan.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., van der Harst P; Department of Cardiology, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Department of Genetics, University of Groningen, University Medical Center Groningen, Groningen, the Netherlands.; Durrer Center for Cardiogenetic Research, Interuniversity Cardiology Institute of the Netherlands (ICIN)-Netherlands Heart Institute, Utrecht, the Netherlands., Kooner JS; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; National Heart and Lung Institute, Imperial College London, London, UK.; Imperial College Healthcare NHS Trust, London, UK., Chambers JC; Department of Epidemiology and Biostatistics, Imperial College London, London, UK.; Ealing Hospital National Health Service (NHS) Trust, Middlesex, UK.; Imperial College Healthcare NHS Trust, London, UK.
Publikováno v:
Nature genetics [Nat Genet] 2015 Nov; Vol. 47 (11), pp. 1282-1293. Date of Electronic Publication: 2015 Sep 21.
Autor:
van der Valk RJ; Department of Epidemiology, Department of Paediatrics, The Generation R Study Group., Kreiner-Møller E; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Kooijman MN; Department of Epidemiology, Department of Paediatrics, The Generation R Study Group., Guxens M; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain., Stergiakouli E; MRC Integrative Epidemiology Unit ., Sääf A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Bradfield JP; Center for Applied Genomics, Abramson Research Center., Geller F; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Hayes MG; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Cousminer DL; Institute for Molecular Medicine Finland., Körner A; Center of Pediatric Research, University Hospital Center Leipzig, University of Leipzig, Leipzig, Germany., Thiering E; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany, Institute of Epidemiology I., Curtin JA; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Myhre R; Division Epidemiology, Department Genes and Environment., Huikari V; Institute of Health Sciences., Joro R; Institute of Biomedicine, Physiology., Kerkhof M; Department of Epidemiology, Groningen Research Institute for Asthma and COPD., Warrington NM; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Pitkänen N; Research Centre of Applied and Preventive Cardiovascular Medicine., Ntalla I; Department of Health Sciences, University of Leicester, Leicester LE1 7RH, UK, Department of Nutrition and Dietetics, Harokopio University of Athens, Athens 11527, Greece., Horikoshi M; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK., Veijola R; Department of Pediatrics, Medical Research Center., Freathy RM; University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK., Teo YY; Saw Swee Hock School of Public Health, Life Science Institute, National University of Singapore, Singapore, Genome Institute of Singapore, Agency for Science, Technology and Research., Barton SJ; MRC Lifecourse Epidemiology Unit., Evans DM; MRC Integrative Epidemiology Unit , University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Kemp JP; MRC Integrative Epidemiology Unit , University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., St Pourcain B; MRC Integrative Epidemiology Unit , Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine, School of Oral and Dental Sciences, University of Bristol, Bristol, UK., Ring SM; MRC Integrative Epidemiology Unit , Avon Longitudinal Study of Parents and Children (ALSPAC), School of Social and Community Medicine., Davey Smith G; MRC Integrative Epidemiology Unit ., Bergström A; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden., Kull I; Department of Clinical Science and Education, Södersjukhuset, Stockholm, Sweden, Sachs' Children's Hospital, Stockholm, Sweden., Hakonarson H; Center for Applied Genomics, Abramson Research Center, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Mentch FD; Center for Applied Genomics, Abramson Research Center., Bisgaard H; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Chawes B; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Stokholm J; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Waage J; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Eriksen P; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Sevelsted A; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Melbye M; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark, Department of Medicine, Stanford School of Medicine, Stanford, USA., van Duijn CM; Department of Epidemiology., Medina-Gomez C; Department of Epidemiology, The Generation R Study Group, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Hofman A; Department of Epidemiology, The Generation R Study Group., de Jongste JC; Department of Paediatrics, The Generation R Study Group., Taal HR; Department of Epidemiology, Department of Paediatrics., Uitterlinden AG; Department of Epidemiology, The Generation R Study Group, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Armstrong LL; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Eriksson J; Institute for Molecular Medicine Finland., Palotie A; Institute for Molecular Medicine Finland, Analytic and Translational Genetics Unit, Department of Medicine, Program in Medical and Population Genetics, Psychiatric & Neurodevelopmental Genetics Unit, Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA., Bustamante M; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain, Centre for Genomic Regulation (CRG), Barcelona, Spain., Estivill X; CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain, Centre for Genomic Regulation (CRG), Barcelona, Spain, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Gonzalez JR; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain., Llop S; CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Foundation for the Promotion of Health and Biomedical Research in the Valencian Region, FISABIO-Public Health, Valencia, Spain., Kiess W; Center of Pediatric Research, University Hospital Center Leipzig, University of Leipzig, Leipzig, Germany., Mahajan A; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK., Flexeder C; Institute of Epidemiology I., Tiesler CM; Division of Metabolic and Nutritional Medicine, Dr. von Hauner Children's Hospital, University of Munich Medical Center, Munich, Germany, Institute of Epidemiology I., Murray CS; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Simpson A; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Magnus P; Division Epidemiology, Norwegian Institute of Public Health, Oslo, Norway., Sengpiel V; Department Obstetrics and Gynecology, Sahlgrenska Academy, Sahlgrenska University Hospital, Gothenburg, Sweden., Hartikainen AL; Institute of Clinical Medicine/Obstetrics and Gynecology., Keinanen-Kiukaanniemi S; Institute of Health Sciences., Lewin A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPE) Centre for Environment and Health., Da Silva Couto Alves A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPE) Centre for Environment and Health., Blakemore AI; Section of Investigative Medicine, Division of Diabetes, Endocrinology, and Metabolism, Faculty of Medicine, Imperial College, London W12 0NN, UK., Buxton JL; Section of Investigative Medicine, Division of Diabetes, Endocrinology, and Metabolism, Faculty of Medicine, Imperial College, London W12 0NN, UK., Kaakinen M; Institute of Health Sciences, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPE) Centre for Environment and Health, Biocenter Oulu, University of Oulu, Oulu, Finland., Rodriguez A; Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPE) Centre for Environment and Health, Department of Psychology, Mid Sweden University, Östersund, Sweden., Sebert S; Institute of Health Sciences., Vaarasmaki M; Department of Obstetrics and Gynecology and MRC Oulu, Oulu University Hospital and University of Oulu, Oulu, Finland., Lakka T; Institute of Biomedicine, Physiology, Kuopio Research Institute of Exercise Medicine, Kuopio, Finland, Department of Clinical Physiology and Nuclear Medicine, Kuopio University Hospital, Kuopio, Finland., Lindi V; Institute of Biomedicine, Physiology., Gehring U; Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands., Postma DS; Groningen Research Institute for Asthma and COPD, Department of Pulmonology., Ang W; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia., Newnham JP; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia., Lyytikäinen LP; Department of Clinical Chemistry, Fimlab Laboratories, Tampere, Finland, Department of Clinical Chemistry, University of Tampere School of Medicine, Tampere, Finland., Pahkala K; Research Centre of Applied and Preventive Cardiovascular Medicine, University of Queensland Diamantina Institute, Translational Research Institute, Brisbane, Queensland, Australia., Raitakari OT; Research Centre of Applied and Preventive Cardiovascular Medicine, Department of Clinical Physiology and Nuclear Medicine., Panoutsopoulou K; Wellcome Trust Sanger Institute, The Morgan Building, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1HH, UK., Zeggini E; Wellcome Trust Sanger Institute, The Morgan Building, Wellcome Trust Genome Campus, Hinxton, Cambridgeshire CB10 1HH, UK., Boomsma DI; Department of Biological Psychology, VU University, Amsterdam, The Netherlands, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, The Netherlands., Groen-Blokhuis M; Department of Biological Psychology, VU University, Amsterdam, The Netherlands, EMGO Institute for Health and Care Research, Amsterdam, The Netherlands, Neuroscience Campus Amsterdam, The Netherlands., Ilonen J; Immunogenetics Laboratory, University of Turku, Turku, Finland, Department of Clinical Microbiology, University of Eastern Finland, Kuopio, Finland., Franke L; Department of Genetics, University of Groningen, University Medical Centre Groningen, The Netherlands., Hirschhorn JN; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, USA, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA, Department of Genetics, Harvard Medical School, USA., Pers TH; Division of Endocrinology and Center for Basic and Translational Obesity Research, Boston Children's Hospital, USA, Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA, USA, Center for Biological Sequence Analysis, Department of Systems Biology, Technical University of Denmark, Denmark., Liang L; Department of Pediatrics, Tampere University Hospital, Tampere, Finland., Huang J; Department of Pediatrics, Tampere University Hospital, Tampere, Finland, Shanghai Institute of Hematology, Rui Jin Hospital Affiliated with Shanghai Jiao Tong University School of Medicine, Shanghai, China., Hocher B; Institute of Nutritional Science, University of Potsdam, Germany, The First Affiliated Hospital of Jinan University, Guangzhou 510630, China, Center for Cardiovascular Research/Institute of Pharmacology, Charité, Berlin, Germany., Knip M; Diabetes and Obesity Research Program, University of Helsinki, Helsinki, Finland, Department of Pediatrics, Tampere University Hospital, Tampere, Finland, Children's Hospital, University of Helsinki and Helsinki University Central Hospital, Helsinki, Finland., Saw SM; Saw Swee Hock School of Public Health, Singapore Eye Research Institute, Singapore, Duke-NUS Graduate Medical School, Singapore., Holloway JW; Human Genetics and Genomic Medicine, Human Development & Health, Faculty of Medicine, University of Southampton, UK., Melén E; Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden, Sachs' Children's Hospital, Stockholm, Sweden., Grant SF; Center for Applied Genomics, Abramson Research Center, Department of Pediatrics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA, Division of Human Genetics, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA., Feenstra B; Department of Epidemiology Research, Statens Serum Institut, Copenhagen, Denmark., Lowe WL; Division of Endocrinology, Metabolism and Molecular Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA., Widén E; Institute for Molecular Medicine Finland., Sergeyev E; Center of Pediatric Research, University Hospital Center Leipzig, University of Leipzig, Leipzig, Germany., Grallert H; Institute of Epidemiology II, Research Unit for Molecular Epidemiology, Helmholtz Zentrum München - German Research Center for Environmental Health, Neuherberg, Germany., Custovic A; Centre for Respiratory Medicine and Allergy, Institute of Inflammation and Repair, University of Manchester and University Hospital of South Manchester, Manchester Academic Health Sciences Centre, Manchester, UK., Jacobsson B; Division Epidemiology, Department Genes and Environment, Department Obstetrics and Gynecology, Sahlgrenska Academy, Sahlgrenska University Hospital, Gothenburg, Sweden., Jarvelin MR; Institute of Health Sciences, Department of Epidemiology and Biostatistics, School of Public Health, Imperial College London, MRC Health Protection Agency (HPE) Centre for Environment and Health, Biocenter Oulu, University of Oulu, Oulu, Finland, Unit of Primary Care, Oulu University Hospital, Kajaanintie 50, P.O.Box 20, FI-90220, Oulu 90029 OYS, Finland, Department of Children and Young People and Families, National Institute for Health and Welfare, Aapistie 1, Box 310, Oulu FI-90101, Finland and., Atalay M; Institute of Biomedicine, Physiology., Koppelman GH; Groningen Research Institute for Asthma and COPD, Beatrix Children's Hospital, Pediatric Pulmonology and Pediatric Allergy, University of Groningen, University Medical Center Groningen, Groningen, The Netherlands., Pennell CE; School of Women's and Infants' Health, The University of Western Australia, Perth, Australia., Niinikoski H; Research Centre of Applied and Preventive Cardiovascular Medicine, Department of Pediatrics, Turku University Hospital, Turku, Finland., Dedoussis GV; Department of Nutrition and Dietetics, Harokopio University of Athens, Athens 11527, Greece., Mccarthy MI; Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford OX3 7LJ, UK, Oxford NIHR Biomedical Research Centre, Churchill Hospital, Oxford OX3 7LJ, UK., Frayling TM; University of Exeter Medical School, Royal Devon and Exeter Hospital, Barrack Road, Exeter EX2 5DW, UK., Sunyer J; Centre for Research in Environmental Epidemiology (CREAL), Barcelona, Spain, CIBER Epidemiología y Salud Pública (CIBERESP), Spain, Pompeu Fabra University (UPF), Barcelona, Catalonia, Spain, IMIM (Hospital del Mar Medical Research Institute), Barcelona, Spain., Timpson NJ; MRC Integrative Epidemiology Unit ., Rivadeneira F; Department of Epidemiology, The Generation R Study Group, Department of Internal Medicine, Erasmus Medical Center, Rotterdam, The Netherlands., Bønnelykke K; Copenhagen Prospective Studies on Asthma in Childhood, Faculty of Health Sciences, University of Copenhagen & Danish Pediatric Asthma Center, Copenhagen University Hospital, Gentofte, Denmark., Jaddoe VW; Department of Epidemiology, Department of Paediatrics, The Generation R Study Group, v.jaddoe@erasmusmc.nl.
Publikováno v:
Human molecular genetics [Hum Mol Genet] 2015 Feb 15; Vol. 24 (4), pp. 1155-68. Date of Electronic Publication: 2014 Oct 03.