Zobrazeno 1 - 10
of 270
pro vyhledávání: '"Da Jia"'
Autor:
Zehua Shang, Sitao Zhang, Jinrui Wang, Lili Zhou, Xinyue Zhang, Daniel D. Billadeau, Peiguo Yang, Lingqiang Zhang, Fangfang Zhou, Peng Bai, Da Jia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Stress granules (SGs) are induced by various environmental stressors, resulting in their compositional and functional heterogeneity. SGs play a crucial role in the antiviral process, owing to their potent translational repressive effects and
Externí odkaz:
https://doaj.org/article/2a58307d4cc34ed0be0b78ff8fafa5ff
Autor:
Yingfeng Tu, Qin Yang, Min Tang, Li Gao, Yuanhao Wang, Jiuqiang Wang, Zhe Liu, Xiaoyu Li, Lejiao Mao, Rui zhen Jia, Yuan Wang, Tie-shan Tang, Pinglong Xu, Yan Liu, Lunzhi Dai, Da Jia
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Liver kinase B1 (LKB1), an evolutionarily conserved serine/threonine kinase, is a master regulator of the AMPK subfamily and controls cellular events such as polarity, proliferation, and energy homeostasis. Functions and mechanisms of the LK
Externí odkaz:
https://doaj.org/article/1003e6c99c3f49bfa3199ad69e3c8016
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-29 (2023)
Abstract Proper subcellular localization is crucial for the functioning of biomacromolecules, including proteins and RNAs. Nuclear transport is a fundamental cellular process that regulates the localization of many macromolecules within the nuclear o
Externí odkaz:
https://doaj.org/article/bd01620fd71c4bdea09c58a5f8970c2e
Publikováno v:
MedComm, Vol 5, Iss 1, Pp n/a-n/a (2024)
Externí odkaz:
https://doaj.org/article/97133f249fd34d519311ac9a2c5d29d8
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-3 (2023)
Externí odkaz:
https://doaj.org/article/d74245a793254efda9f775fe59b1befc
Autor:
Zhe Liu, Shuai Tan, Lianyu Zhou, Li Chen, Mingfeng Liu, Wang Wang, Yingying Tang, Qin Yang, Sensen Chi, Peiyan Jiang, Yue Zhang, Yonghua Cui, Junhong Qin, Xiao Hu, Shenglong Li, Qi Liu, Lu Chen, Song Li, Ezra Burstein, Wei Li, Xiaohu Zhang, Xianming Mo, Da Jia
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 8, Iss 1, Pp 1-15 (2023)
Abstract Autism spectrum disorder (ASD) affects 1–2% of all children and poses a great social and economic challenge for the globe. As a highly heterogeneous neurodevelopmental disorder, the development of its treatment is extremely challenging. Mu
Externí odkaz:
https://doaj.org/article/0248d94dfd984dbbbe3bac557e3ccf0c
Publikováno v:
MedComm – Oncology, Vol 2, Iss 2, Pp n/a-n/a (2023)
Externí odkaz:
https://doaj.org/article/9ccd140c72824a1eb23fcfa4fe029579
Publikováno v:
Signal Transduction and Targeted Therapy, Vol 7, Iss 1, Pp 1-13 (2022)
Abstract Traditional drug discovery mainly focuses on direct regulation of protein activity. The development and application of protein activity modulators, particularly inhibitors, has been the mainstream in drug development. In recent years, PROteo
Externí odkaz:
https://doaj.org/article/15f185af49ac4891a699db4acf7b6d93
Publikováno v:
MedComm, Vol 2, Iss 4, Pp 798-809 (2021)
Abstract SARS‐CoV‐2 is an enveloped positive‐sense RNA virus that depends on host factors for all stages of its life. Membrane receptor ACE2 is a well‐established factor for SARS‐CoV‐2 docking. In addition to ACE2, whole‐genome genetic
Externí odkaz:
https://doaj.org/article/81dc85754bdb44eda48af952cf2a7f44
Publikováno v:
Cell Discovery, Vol 7, Iss 1, Pp 1-5 (2021)
Externí odkaz:
https://doaj.org/article/fcecd16a50bc4fa8b842a7884e0d2009