Zobrazeno 1 - 10
of 1 625
pro vyhledávání: '"Da FU"'
Autor:
Renfei Wu, Jingwei Li, Alexandra Aicher, Ke Jiang, Serena Tondi, Shuang Dong, Quan Zheng, Siqi Tang, Minchun Chen, Zhenyang Guo, Berina Šabanović, Preeta Ananthanarayanan, Lingxi Jiang, Anna Sapino, Chenlei Wen, Da Fu, Baiyong Shen, Christopher Heeschen
Publikováno v:
Advanced Science, Vol 11, Iss 42, Pp n/a-n/a (2024)
Abstract Pancreatic ductal adenocarcinoma (PDAC) is a highly metastatic and lethal disease. Gasdermins are primarily associated with necrosis via membrane permeabilization and pyroptosis, a lytic pro‐inflammatory type of cell death. In this study,
Externí odkaz:
https://doaj.org/article/4a1d2e567e754b1694f000746f5148e4
Publikováno v:
Zhongguo shuxue zazhi, Vol 37, Iss 4, Pp 392-398 (2024)
Objective To perform pre-transfusion examination and major crossmatch test using CD47 anti-idiotypic antibody (CD47 AID) (method 1) and reagent lack of anti-IgG4 anti-human globulin(method 2) in patients treated with CD47 monoclonal antibodies, and e
Externí odkaz:
https://doaj.org/article/1142440d56734d2caf5fc09e5b2be558
Autor:
Dongjie Chen, Pengyi Liu, Xiongxiong Lu, Jingfeng Li, Debin Qi, Longjun Zang, Jiayu Lin, Yihao Liu, Shuyu Zhai, Da Fu, Yuanchi Weng, Hongzhe Li, Baiyong Shen
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-19 (2024)
Abstract Background Immunotherapy has emerged as a potent clinical approach for cancer treatment, but only subsets of cancer patients can benefit from it. Targeting lactate metabolism (LM) in tumor cells as a method to potentiate anti-tumor immune re
Externí odkaz:
https://doaj.org/article/77865204698b4594b7d6674ca7230b56
Autor:
Jiajia Tang, Quan Zheng, Qi Wang, Yaru Zhao, Preeta Ananthanarayanan, Chiara Reina, Berina Šabanović, Ke Jiang, Ming-Hsin Yang, Clara Csilla Meny, Huimin Wang, Mette Ø. Agerbaek, Thomas Mandel Clausen, Tobias Gustavsson, Chenlei Wen, Felice Borghi, Alfredo Mellano, Elisabetta Fenocchio, Vanesa Gregorc, Anna Sapino, Thor G. Theander, Da Fu, Alexandra Aicher, Ali Salanti, Baiyong Shen, Christopher Heeschen
Publikováno v:
Cell Reports Medicine, Vol 5, Iss 9, Pp 101692- (2024)
Summary: Pancreatic ductal adenocarcinoma (PDAC) poses significant clinical challenges, often presenting as unresectable with limited biopsy options. Here, we show that circulating tumor cells (CTCs) offer a promising alternative, serving as a “liq
Externí odkaz:
https://doaj.org/article/ed0af2f0abc443e89c00860a71176afe
Autor:
Sha Li, Pei Xue, Xun Diao, Qi-Yu Fan, Kun Ye, Xiao-Mei Tang, Jia Liu, Zhong-Yan Huang, Qing-Hai Tang, Cheng-You Jia, Rui Xin, Zhong-Wei Lv, Ji-Bin Liu, Yu-Shui Ma, Da Fu
Publikováno v:
Journal of Advanced Research, Vol 54, Iss , Pp 133-146 (2023)
Background: Aberrations in MYC underlie a large proportion of liver hepatocellular carcinoma (LIHC) cases; however, MYC is difficult to target because of its undruggable structure. We aimed to uncover MYC-associated molecular targets to provide new s
Externí odkaz:
https://doaj.org/article/5b1dc4ef0d4d432f81b40b8b4b5c5ebe
Autor:
Shuyu Zhai, Jiewei Lin, Yuchen Ji, Ronghao Zhang, Zehui Zhang, Yizhi Cao, Yang Liu, Xiaomei Tang, Jia Liu, Pengyi Liu, Jiayu Lin, Fanlu Li, Hongzhe Li, Yusheng Shi, Da Fu, Xiaxing Deng, Baiyong Shen
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-20 (2023)
Abstract The extensively activated Notch signaling pathway in pancreatic cancer cells is important in carcinogenesis, chemoresistance, and recurrence. Targeting this pathway is a promising therapeutic strategy for pancreatic cancer; however, few succ
Externí odkaz:
https://doaj.org/article/719593f280154ba789a1dcbf0ab6b40d
Autor:
Xiangwan Miao, Hao Wang, Cui Fan, QianQian Song, Rui Ding, Jichang Wu, Haixia Hu, Kaili Chen, Peilin Ji, Qing Wen, Minmin Shi, Bin Ye, Da Fu, Mingliang Xiang
Publikováno v:
Cancer Cell International, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Objective Systemic chemotherapy is the first-line therapeutic option for head and neck squamous cell carcinoma (HNSCC), but it often fails. This study aimed to develop an effective prognostic model for evaluating the therapeutic effects of s
Externí odkaz:
https://doaj.org/article/27b604b1b4624c23bd9b44da0f61ff05
Autor:
Meng Zhang, Lin Jiang, Xin-Yun Liu, Fu-Xing Liu, Hui Zhang, Yan-Juan Zhang, Xiao-Mei Tang, Yu-Shui Ma, Hui-Yi Wu, Xun Diao, Chun Yang, Ji-Bin Liu, Da Fu, Jie Zhang, Hong Yu
Publikováno v:
Heliyon, Vol 10, Iss 1, Pp e24287- (2024)
Pancreatic adenocarcinoma (PAAD) remains challenging to diagnose and treat clinically due to its difficult early diagnosis, low surgical resection rate, and high risk of postoperative recurrence and metastasis. SMAD4 is a classical mutated gene in pa
Externí odkaz:
https://doaj.org/article/e81d98cbd2484fa6abd4712c96ba4ad9
Autor:
Yuan Wang, Zhenchang Jia, Chenxi Liang, Yunfei He, Min Cong, Qiuyao Wu, Pu Tian, Dasa He, Xiang Miao, Beibei Sun, Yue Yin, Chao Peng, Feng Yao, Da Fu, Yajun Liang, Peiyuan Zhang, Hua Xiong, Guohong Hu
Publikováno v:
Cell Discovery, Vol 9, Iss 1, Pp 1-15 (2023)
Abstract Immune checkpoint blockade (ICB) therapy targeting PD-1/PD-L1 has shown durable clinical benefits in lung cancer. However, many patients respond poorly to ICB treatment, underscoring an incomplete understanding of PD-L1 regulation and therap
Externí odkaz:
https://doaj.org/article/2de89657795f465f84248cb8a2785d69
Autor:
Xue-Chen Yu, Ji-Bin Liu, Qing-Hai Tang, Xun Diao, Qi-Yu Fan, Zhong-Yan Huang, Xiao-Mei Tang, Sha Li, Yong-Feng Cao, Yu-Shui Ma, Da Fu
Publikováno v:
Annals of Medicine, Vol 54, Iss 1, Pp 2785-2795 (2022)
Background Improvements in screening and imaging technologies and treatment of liver disease have influenced the trend in diagnosis for stage I liver cancer. In this article, recent trends in age, incidence, tumour size, and survival of different sta
Externí odkaz:
https://doaj.org/article/c2338364dbd14e679fdfd1088e96a84b