Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Da, Cooney"'
Publikováno v:
Europe PubMed Central
With increasing awareness of the mitochondrial toxicity associated with certain 2',3'-dideoxynucleosides used in anti-human immunodeficiency virus therapy, procedures for quantitative analyses of drug effects on mitochondrial DNA (mtDNA) have assumed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c7bc307346cd5bc4ec88f6d68c6ec4b4
https://pubmed.ncbi.nlm.nih.gov/7808425
https://pubmed.ncbi.nlm.nih.gov/7808425
Autor:
Hao Z, Da, Cooney, Nr, Hartman, CARLO FEDERICO PERNO, Fridland A, Al, Devico, Mg, Sarngadharan, Broder S, Dg, Johns
Publikováno v:
Europe PubMed Central
Mitsuya and Broder [Proc. Natl. Acad. Sci. USA 83:1911-1915 (1986)] demonstrated that every purine (adenosine, guanosine, and inosine) and pyrimidine (cytidine and thymidine) nucleoside containing the 2',3'-dideoxyribose configuration, when evaluated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::51090ce43bdecd73c32073e38d0f0ec1
https://pubmed.ncbi.nlm.nih.gov/2459590
https://pubmed.ncbi.nlm.nih.gov/2459590
Publikováno v:
Europe PubMed Central
The pathways of 2',3'-dideoxyadenosine (ddAdo) metabolism, a selective inhibitor of the replication of human immunodeficiency virus, were investigated with use of the human T-lymphoid cell line CCRF-CEM which is deficient in either deoxycytidine kina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::b99f04184935ab086386bd45f23a45e7
https://pubmed.ncbi.nlm.nih.gov/3262616
https://pubmed.ncbi.nlm.nih.gov/3262616
Autor:
Hao Z, Da, Cooney, Farquhar D, CARLO FEDERICO PERNO, Zhang K, Masood R, Wilson Y, Nr, Hartman, Balzarini J, Dg, Johns
Publikováno v:
Europe PubMed Central
2',3'-Dideoxyuridine (ddUrd) exhibits poor if any anti-human immunodeficiency virus (HIV) activity in ATH8 and MT-4 cells. This is in agreement with the failure of ddUrd to be efficiently anabolized intracellularly to its 5'-triphosphate metabolite.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::de48b79642b050c7f6896b2207ef7533
http://europepmc.org/abstract/med/1689452
http://europepmc.org/abstract/med/1689452
Publikováno v:
Europe PubMed Central
Inosine 5 -monophosphate dehydrogenase (IMPDH) is a rate-limiting enzyme for the synthesis of GTP and dGTP. Two isoforms of IMPDH have been identified. IMPDH Type I is ubiquitous and predominantly present in normal cells, whereas IMPDH Type II is pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c0474d7fb4a4838a40177f4dd050aa0c
http://europepmc.org/abstract/med/10390601
http://europepmc.org/abstract/med/10390601
Autor:
CARLO FEDERICO PERNO, Da, Cooney, Wy, Gao, Hao Z, Dg, Johns, Foli A, Nr, Hartman, Caliò R, Broder S, Yarchoan R
Publikováno v:
Europe PubMed Central
Cells of the monocyte lineage are important targets for the replication of human immunodeficiency virus (HIV). Our group and others have previously shown that granulocyte-macrophage colony-stimulating factor (GM-CSF) stimulates HIV replication in mon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::28b3253e9d3ef7842faa4cee92a3329d
http://europepmc.org/abstract/med/1379854
http://europepmc.org/abstract/med/1379854
Autor:
Agbaria R; Department of Clinical Pharmacology, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Candotti F, Kelley JA, Hao Z, Johns DG, Cooney DA, Blaese RM, Ford H Jr
Publikováno v:
Biochemical and biophysical research communications [Biochem Biophys Res Commun] 2001 Nov 30; Vol. 289 (2), pp. 525-30.
Autor:
Jayaram HN; Department of Biochemistry and Molecular Biology and Laboratory for Experimental Oncology, Indiana University School of Medicine, 699 West St., Indianapolis, IN 46202-5119, USA., Cooney DA, Grusch M, Krupitza G
Publikováno v:
Current medicinal chemistry [Curr Med Chem] 1999 Jul; Vol. 6 (7), pp. 561-74.
Autor:
Jeong LS; Laboratory of Medicinal Chemistry, Division of Basic Sciences, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA., Buenger G, McCormack JJ, Cooney DA, Hao Z, Marquez VE
Publikováno v:
Journal of medicinal chemistry [J Med Chem] 1998 Jul 02; Vol. 41 (14), pp. 2572-8.
Autor:
Jayaram HN; Laboratory for Experimental Oncology, Indiana University School of Medicine, Indianapolis 46202-5200, USA., O'Connor A, Grant MR, Yang H, Grieco PA, Cooney DA
Publikováno v:
Journal of experimental therapeutics & oncology [J Exp Ther Oncol] 1996 Sep; Vol. 1 (5), pp. 278-85.