Zobrazeno 1 - 10
of 29
pro vyhledávání: '"DWIGHT S. FULLERTON"'
Publikováno v:
Expert Review of Pharmacoeconomics & Outcomes Research. 11:27-39
Darunavir boosted with ritonavir (DRV/r) in combination with other antiretrovirals (ARVs) was initially approved in 2006 for the treatment of HIV infection in ARV treatment-experienced adults and has subsequently been approved for use in treatment-na
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c2ab93bcbf54bdebfed6bd7b1ff5539
https://doi.org/10.1586/erp.10.88
https://doi.org/10.1586/erp.10.88
Publikováno v:
Molecular and Cellular Biochemistry. 94:157-165
The structure-activity relationships of the genin moieties of digitalis glycosides are commonly elucidated by determining the inhibitory potency of a variety of genins toward the plasma membrane Na+, K(+)-ATPase; qualitatively these relationships app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8af7e11d2d027f70eb1536d8d9314c86
https://doi.org/10.1007/bf00214122
https://doi.org/10.1007/bf00214122
Publikováno v:
American pharmacy. (12)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ff80c4556838e9344f83ba52b84388a
https://pubmed.ncbi.nlm.nih.gov/1285553
https://pubmed.ncbi.nlm.nih.gov/1285553
Publikováno v:
Tetrahedron. 40:1121-1133
Earlier studies have shown that the β-D-digitoxose (2,6-dideoxy-β-D-mannopyranose) directly attached to the cardiac glycoside steroid C3 has the greatest effect on biological activity. This report describes the synthesis of eight digitoxosides (2a-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::618ea5089ba45e8a4469e565b0e0db32
https://doi.org/10.1016/s0040-4020(01)99316-0
https://doi.org/10.1016/s0040-4020(01)99316-0
Autor:
Masaru Kihara, Dwight S. Fullerton, Khalil Ahmed, Tamboue Deffo, Robert R. Becker, Reginald McParland, Bruce M. Simat, Arthur H. L. From, Michael I. Schimerlik
Publikováno v:
Biochemistry. 22:6303-6309
The synthesis and properties of a radiolabeled glycoside photoaffinity probe, [3H]-(3 beta,5 beta,14 beta, 20E)-24-azido-3-[(2,6-dideoxy-beta-D-ribo-hexopyranosyl) oxy]-14-hydroxy-21-norchol-20(22)-en-23-one, containing the photoactive group at the C
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8f219da99d6dec850de9391bc88292c
https://doi.org/10.1021/bi00295a041
https://doi.org/10.1021/bi00295a041
Publikováno v:
Trends in Pharmacological Sciences. 6:279-282
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12e3f428653b826cc3d5d4b8951d3189
https://doi.org/10.1016/0165-6147(85)90128-2
https://doi.org/10.1016/0165-6147(85)90128-2
Publikováno v:
Tetrahedron. 41:5427-5438
As part of a continuing study of cardiac g1ycos1des,1,2 stereoselective syntheses of the four possible glucosides of digitoxigenin were developed via the thermodynamically produced tetra-O-benzyl-D- and L-glucosyl α-trichloroacetaimidates 2α and 11
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7d3f16f854652031a1ee1f0e971ec97c
https://doi.org/10.1016/s0040-4020(01)91342-0
https://doi.org/10.1016/s0040-4020(01)91342-0
Autor:
Douglas C. Rohrer, Thomas M. Gilman, Khalil Ahmed, Arthur H. L. From, William L. Duax, Dwight S. Fullerton, Marvin C. Pankaskie
Publikováno v:
Journal of Medicinal Chemistry. 20:841-844
22-Methylene-3beta-hydroxy-5beta,20(S)-card-14-enolide (11) and 22-methylene-3beta-hydroxy-5beta,20(R)-card-14-enolide (12) were synthesized from digitoxin (1). Attempts to prepare the 14beta-hydroxy-22-methylene analogues were unsuccessful. The 20(R
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02557ab9d0522e08fc9654fa894b3d0f
https://doi.org/10.1021/jm00216a022
https://doi.org/10.1021/jm00216a022
Autor:
Khalil Ahmed, Arthur H. L. From, Robert R. Mayrand, Charles J. Billington, Bruce M. Simat, John E. Morley, Dwight S. Fullerton
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 56:925-929
Ouabain binding and electrolyte concentrations of erythrocytes, and Na+, K+-ATPase activity of red cell ghosts were measured in normal and obese subjects, ranging from 88-257% of their ideal body weight. All three independent measurements were virtua
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48530f188490bd4be15cd62925dff7f4
https://doi.org/10.1210/jcem-56-5-925
https://doi.org/10.1210/jcem-56-5-925
Autor:
Douglas C. Rohrer, Arthur H. L. From, Tamboue Deffo, Khalil Ahmed, Dwight S. Fullerton, H. Rathore, Masaru Kihara
Publikováno v:
Journal of the American Chemical Society. 106:8269-8276
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bbd303c4480a0cf5c3c3b81e5e7d4f87
https://doi.org/10.1021/ja00338a043
https://doi.org/10.1021/ja00338a043