Adults prenatally exposed to the Dutch Famine exhibit a metabolic signature associated with a broad spectrum of common diseases

Autor: M. Jazmin Taeubert, Thomas B. Kuipers, Jiayi Zhou, Chihua Li, Shuang Wang, Tian Wang, Elmar W. Tobi, BBMRI-NL Metabolomics consortium, Daniel W. Belsky, L. H. Lumey, Bastiaan T. Heijmans

Publikováno v: BMC Medicine, Vol 22, Iss 1, Pp 1-10 (2024)

Abstract Background Exposure to famine in the prenatal period is associated with an increased risk of metabolic disease, including obesity and type 2 diabetes. We employed nuclear magnetic resonance (NMR) metabolomic profiling to identify the metabol

Externí odkaz: https://doaj.org/article/115855a307414678ac53b013ac2278ed

Lessons learned from 25 Years of Research into Long term Consequences of Prenatal Exposure to the Dutch famine 1944–45: The Dutch famine Birth Cohort.

Autor: De Rooij, Susanne R.^1,2 s.r.derooij@amsterdamumc.nl, Bleker, Laura S.¹, Painter, Rebecca C.³, Ravelli, Anita C.^3,4, Roseboom, Tessa J.^1,2,3

Publikováno v: International Journal of Environmental Health Research. Jul2022, Vol. 32 Issue 7, p1432-1446. 15p. 1 Diagram, 1 Chart.

Effects of prenatal exposure to the 1944–45 Dutch famine and glucocorticoid receptor polymorphisms on later life PTSD susceptibility.

Autor: Gultig, Kayleigh D.¹ (AUTHOR), de Rooij, Susanne R.² (AUTHOR), Hilberdink, Charlotte E.³ (AUTHOR), Olff, Miranda^1,4 (AUTHOR), Roseboom, Tessa J.⁵ (AUTHOR), van Zuiden, Mirjam^1,6 (AUTHOR) m.vanzuiden@uu.nl

Publikováno v: European Journal of Psychotraumatology. 2023, Vol. 14 Issue 2, p1-14. 14p.

Effects of prenatal exposure to the 1944–45 Dutch famine and glucocorticoid receptor polymorphisms on later life PTSD susceptibility

Autor: Kayleigh D. Gultig, Susanne R. de Rooij, Charlotte E. Hilberdink, Miranda Olff, Tessa J. Roseboom, Mirjam van Zuiden

Publikováno v: European Journal of Psychotraumatology, Vol 14, Iss 2 (2023)

Background: Exposure to adversity in utero is thought to increase susceptibility to develop posttraumatic stress disorder (PTSD) following later life trauma, due to neurobiological programming effects during critical developmental periods. It remains

Externí odkaz: https://doaj.org/article/67a15c9f076e4ff78c0b32afb77ce615

Adults prenatally exposed to the Dutch Famine exhibit a metabolic signature associated with a broad spectrum of common diseases.

Autor: Taeubert MJ; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Kuipers TB; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Zhou J; Butler Columbia Aging Center, Columbia University, New York, United States., Li C; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, United States., Wang S; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, United States., Wang T; Department of Biostatistics, Mailman School of Public Health, Columbia University, New York, United States., Tobi EW; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands., Belsky DW; Butler Columbia Aging Center, Columbia University, New York, United States.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, United States., Lumey LH; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, United States., Heijmans BT; Department of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.

Publikováno v: MedRxiv : the preprint server for health sciences [medRxiv] 2024 Apr 05. Date of Electronic Publication: 2024 Apr 05.