pERK-dependent defective TCR-mediated activation of CD4+ T cells in end-stage renal disease patients

Autor: Ling Huang, Nicolle H. R. Litjens, Nynke M. Kannegieter, Mariska Klepper, Carla C. Baan, Michiel G. H. Betjes

Publikováno v: Immunity & Ageing, Vol 14, Iss 1, Pp 1-14 (2017)

Abstract Background Patients with end-stage renal disease (ESRD) have an impaired immune response with a prematurely aged T-cell system. Mitogen-activated protein kinases (MAPKs) including extracellular signal-regulated kinase (ERK) and p38, regulate

Externí odkaz: https://doaj.org/article/7060b6c5185b4bfe94a978062f620a57

Fetal Programming of the Endocrine Pancreas: Impact of a Maternal Low-Protein Diet on Gene Expression in the Perinatal Rat Pancreas

Autor: Louise Winkel, Morten Rasmussen, Louise Larsen, Louise T. Dalgaard, Jens H. Nielsen

Publikováno v: International Journal of Molecular Sciences; Volume 23; Issue 19; Pages: 11057
Winkel, L, Rasmussen, M, Larsen, L, Dalgaard, L T & Nielsen, J H 2022, ' Fetal Programming of the Endocrine Pancreas : Impact of a Maternal Low-Protein Diet on Gene Expression in the Perinatal Rat Pancreas ', International Journal of Molecular Sciences, vol. 23, no. 19, 11057 . https://doi.org/10.3390/ijms231911057

In rats, the time of birth is characterized by a transient rise in beta cell replication, as well as beta cell neogenesis and the functional maturation of the endocrine pancreas. However, the knowledge of the gene expression during this period of bet

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acb71662dd53da9e088cc6deb8282b30
https://doi.org/10.3390/ijms231911057

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