Zobrazeno 1 - 10
of 127
pro vyhledávání: '"DSSP (hydrogen bond estimation algorithm)"'
Amino acid side chain contribution to protein FTIR spectra: impact on secondary structure evaluation
Autor:
Erik Goormaghtigh, Joëlle De Meutter
Publikováno v:
European Biophysics Journal
Prediction of protein secondary structure from FTIR spectra usually relies on the absorbance in the amide I–amide II regionof the spectrum. It assumes that the absorbance in this spectral region, i.e., roughly 1700–1500 cm−1 is solely arising f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e3bfc46de27be027d72e93bf5d4e0c5
http://europepmc.org/articles/PMC8189991
http://europepmc.org/articles/PMC8189991
Publikováno v:
Human Mutation, 42, 7, pp. 799-810
Human Mutation
Human Mutation, 42, 799-810
Human Mutation
Human Mutation, 42, 799-810
Hereditary disorders are frequently caused by genetic variants that affect pre‐messenger RNA splicing. Though genetic variants in the canonical splice motifs are almost always disrupting splicing, the pathogenicity of variants in the noncanonical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ff28acfd63c6fd74bff5310d73fcd87
https://hdl.handle.net/2066/235593
https://hdl.handle.net/2066/235593
Autor:
Weiwei Xue, Xianquan Ming, Haiqing Zhan, Feng Zhan, Rong Huang, Hongyan Yu, Gao Tu, Jing Jing
Publikováno v:
Physical Chemistry Chemical Physics. 23:11717-11726
Tau misfolding plays a significant role in some neurodegenerative diseases such as Alzheimer's disease (AD). It is intrinsically disordered and highly soluble under normal physiological conditions. While the protein will aggregate to form paired heli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22019a5855a9c418042739c30e70213b
https://doi.org/10.1039/d0cp05744d
https://doi.org/10.1039/d0cp05744d
Publikováno v:
Restaurant and hotel consulting. Innovations. 3:237-251
The topicality. Serious changes in the structure of nutrition associated with changes in lifestyle, a decrease in energy consumption, lead to the fact that none of the population groups receives from the food consumed the amount of essential nutrient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::70a6b1dab902a7349daff3fbbff214b8
https://doi.org/10.31866/2616-7468.3.2.2020.219708
https://doi.org/10.31866/2616-7468.3.2.2020.219708
Autor:
Erik Goormaghtigh, Joëlle De Meutter
Publikováno v:
Analytical Chemistry. 93:1561-1568
Obtaining protein secondary structure content from high-resolutionstructures requires definitions and thresholds for the various parameters involved, typicallyhydrogen bond energy or length/angle and backbone φ/ψ angles. Several definitions arecurr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7db32983faf4cac6617cfa204d43f292
https://doi.org/10.1021/acs.analchem.0c03943
https://doi.org/10.1021/acs.analchem.0c03943
Publikováno v:
The Protein Journal. 39:308-317
Surface accessibility of different types of the same elements of secondary structure has been studied in 10 non-redundant sets of proteins (total number of three-dimensional structures is 1730) with a help of DSSP (Dictionary of Secondary Structure o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::43d3303d64152326d5f91985a7ff3f2f
https://doi.org/10.1007/s10930-020-09905-0
https://doi.org/10.1007/s10930-020-09905-0
Autor:
Joëlle De Meutter, Erik Goormaghtigh
Publikováno v:
Computational and Structural Biotechnology Journal
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1864-1876 (2020)
Computational and Structural Biotechnology Journal, 18
Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 1864-1876 (2020)
Computational and Structural Biotechnology Journal, 18
While several Raman, CD or FTIR spectral libraries are available for well-characterized proteins of known structure, proteins themselves are usually very difficult to acquire, preventing a convenient calibration of new instruments and new recording m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a79f46457b2e725c3df93f685ede4519
http://europepmc.org/articles/PMC7369421
http://europepmc.org/articles/PMC7369421
Autor:
Nikita Jain, S. Udhaya Kumar, Prangya Paramita Jena, Siva Ramamoorthy, Hatem Zayed, C. George Priya Doss, D Thirumal Kumar
Publikováno v:
Journal of Biomolecular Structure and Dynamics. 39:1795-1810
Krabbe disease (KD), also known as globoid cell leukodystrophy disease, is an autosomal recessive lysosomal storage genetic disorder, which is caused by the deficiency of galactocerebrosidase (GALC) coding gene (GALC). This study aimed to use extensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de45ae04c6ec54d5d8b7f7e9728db1d3
https://doi.org/10.1080/07391102.2020.1742790
https://doi.org/10.1080/07391102.2020.1742790
Autor:
Chen Keasar, Tomer Sidi
Publikováno v:
Bioinformatics. 36:3733-3738
Motivation The Protein Data Bank (PDB), the ultimate source for data in structural biology, is inherently imbalanced. To alleviate biases, virtually all structural biology studies use nonredundant (NR) subsets of the PDB, which include only a fractio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdd737ad00e649ada74e28f0c6a7127d
https://doi.org/10.1093/bioinformatics/btaa196
https://doi.org/10.1093/bioinformatics/btaa196
The development of AlphaFold2 was a paradigm-shift in the structural biology community; herein we assess the ability of AlphaFold2 to predict disordered regions against traditional sequence-based disorder predictors. We find that a näaive use of Dic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5cc550547372d72650ab41879d53133c
https://doi.org/10.1101/2021.09.27.461910
https://doi.org/10.1101/2021.09.27.461910
