Zobrazeno 1 - 10
of 73
pro vyhledávání: '"DSS, dextran sodium sulfate"'
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 3, Pp 843-856 (2022)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
The epithelial lining of the intestine, particularly the stem cell compartment, is affected by harsh conditions in the luminal environment and also is susceptible to genotoxic agents such as radiation and chemotherapy. Therefore, the ability for inte
Autor:
Jui-Ping Weng, Shu-Chen Wei, Xin-Yu Chang, Liang-Chuan Lai, Po-Yu Lin, Yen-Hsuan Ni, Linda C.H. Yu, Yi-Hsuan Li, Yung-Ming Jeng, Yin-Wen Shue, Jin-Town Wang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 57-79 (2022)
Cellular and Molecular Gastroenterology and Hepatology, Vol 13, Iss 1, Pp 57-79 (2022)
Background & Aims Microbiota dysbiosis and mucosa-associated bacteria are involved in colorectal cancer progression. We hypothesize that an interaction between virulent pathobionts and epithelial defense promotes tumorigenesis. Methods Chemical-induc
Autor:
Kenneth W. Simpson, Andrew J. Dannenberg, David C. Montrose, Chen Jiao, Lingsong Meng, Martin T. Wells, Srijani Basu, Hanhan Wang, Akihiko Oka, Juan R. Cubillos-Ruiz, Melanie Johncilla, Jeremy Herzog, Xi Kathy Zhou, Belgin Dogan, Zhangjun Fei, Shiying Zhang, Diana K. Morales, R. Balfour Sartor, Ryohei Nishiguchi, Hannah A Staab
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The incidence of inflammatory bowel diseases has increased over the last half century, suggesting a role for dietary factors. Fructose consumption has increased in recent years. Recently, a high fructose diet (HFrD) was shown to enh
Autor:
Iulia Oancea, Andy Wu, Michael A. McGuckin, Sumaira Z. Hasnain, Rabina Giri, John D. Hooper, Veronika Schreiber, Brett C McWhinney, Julie M. Davies, Jakob Begun, Yonghua Sheng, David P. Fairlie, Saleh Y. Alabbas, Gregor Kijanka, Yaowu He, Ramya Movva, Andrew J. Lucke, Timothy H. Florin
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 33-53 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims Chronic bowel inflammation increases the risk of colon cancer; colitis-associated cancer (CAC). Thiopurine treatments are associated with a reduction in dysplasia and CAC in inflammatory bowel disease (IBD). Abnormal Wnt/β-catenin
Autor:
Aralia Leon-Coria, Manish Kumar, Matthew Workentine, France Moreau, Michael Surette, Kris Chadee
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 1, Pp 77-98 (2021)
Background & Aims Alterations in intestinal MUC2 mucin and microbial diversity are closely linked with important intestinal pathologies; however, their impact on each other and on intestinal pathogenesis has been vaguely characterized. Therefore, it
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 4, Pp 1177-1197 (2021)
Inflammatory bowel disease (IBD) patients have an increased risk of developing colitis-associated colon cancer (CAC); however, the basis for inflammation-induced genetic damage requisite for neoplasia is unclear. Several studies have shown that IBD p
Autor:
Gemma Navarro, Alvaro Lladser, Javier Campos, Alexandra Espinoza, Francisco Contreras, Carolina Prado, Iu Raïch, Rodrigo Pacheco, Rafael Franco, Francisco Osorio-Barrios, Ernesto Lopez, Valentina Ugalde
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 2, Pp 489-506 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background and aims: CD4+ T cells constitute central players in inflammatory bowel diseases (IBDs), driving inflammation in the gut mucosa. Current evidence indicates that CCR9 and the integrin α4β7 are necessary and sufficient to imprint colonic h
Autor:
Anita Krnjic, Vineeta Khare, Maximilian Baumgartner, Ildiko Mesteri, Christoph Gasche, Kyle Dammann, Adrian Frick, Kristine Jimenez, Christina Gmainer, Michaela Lang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 11, Iss 3, Pp 892-907.e1 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims p21-activated kinase-1 (PAK1) belongs to a family of serine-threonine kinases and contributes to cellular pathways such as nuclear factor-κB (NF-κB), mitogen-activated protein kinase (MAPK), phosphatidylinositol 3-kinase/protein k
Autor:
Hamid M. Said, Jonathan Skupsky, Michael D. Cahalan, Manando Nakasaki, Subrata Sabui, Michael Hwang
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 4, Pp 557-567 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 9, iss 4
Cellular and Molecular Gastroenterology and Hepatology
Cellular and molecular gastroenterology and hepatology, vol 9, iss 4
Background & Aims Biotin is a water-soluble vitamin that is indispensable for human health. Biotin deficiency can cause failure-to-thrive, immunodeficiency, alopecia, dermatitis, and conjunctivitis. We previously reported that biotin deficiency also
Autor:
Shannon Moonah, Koji Watanabe, Swagata Ghosh, Nona M. Jiang, Richard Bucala, Mahmut Parlak, Laura Farr
Publikováno v:
Cellular and Molecular Gastroenterology and Hepatology, Vol 10, Iss 1, Pp 101-112 (2020)
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology
Background & Aims The inflammatory response to intestinal damage promotes healing through mechanisms that are incompletely understood. Gene expression of cluster of differentiation 74 (CD74), the receptor for cytokine macrophage migration inhibitory