Zobrazeno 1 - 10
of 531
pro vyhledávání: '"DS Latchman"'
Autor:
James McCormick, DS Latchman, N. Suleman, Richard A. Knight, Anastasis Stephanou, Tiziano M. Scarabelli
Publikováno v:
Journal of Cellular and Molecular Medicine
Previous studies have shown that the transcription factor signal transducer and activator of transcription 1 (STAT1) activation is increased in primary cardiac myocytes exposed to simulated ischaemia/reperfusion injury. This promotes apoptotic cell d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c3753e1b7b734ec5f81e25fb99c562a
https://doi.org/10.1111/j.1582-4934.2011.01323.x
https://doi.org/10.1111/j.1582-4934.2011.01323.x
Publikováno v:
BioProcessing Journal. 6:8-14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e0bfdeef4bd234db36423a5f77edabb5
https://doi.org/10.12665/j61.jayasinghe
https://doi.org/10.12665/j61.jayasinghe
Autor:
Christopher Carroll, Kevin Mills, Wendy E. Heywood, David A. Isenberg, IP Giles, Silvia S. Pierangeli, Anastasia Lambrianides, Paul A. Townsend, C Pericleous, DS Latchman, Anisur Rahman
Publikováno v:
Rheumatology. 46:i78-i81
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7af2985b69326242db2592b1867c733a
https://doi.org/10.1093/rheumatology/kem1020
https://doi.org/10.1093/rheumatology/kem1020
Autor:
KM Lawrence, DS Latchman
Publikováno v:
Mini-Reviews in Medicinal Chemistry. 6:1119-1126
The study of the Urocortin family of peptides is becoming increasingly important clinically, as new discoveries have revealed that their roles in the body are extremely diverse. They range from being involved in the aetiology of affective disorders,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b9986aba5d8c3d39787799f88124e7c
https://doi.org/10.2174/138955706778560111
https://doi.org/10.2174/138955706778560111
Publikováno v:
Experimental & Molecular Medicine. 37:311-322
Preconditioning of the myocardium rapidly induces a number of transcription factors, which are likely to be responsible for a cascade of transcriptional changes underlying the development of delayed adaptation. Identifying these changes provides insi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b823de07451115ff139ca4afee08f4b
https://doi.org/10.1038/emm.2005.41
https://doi.org/10.1038/emm.2005.41
Autor:
James McCormick, Christopher Carroll, Sean M. Davidson, Anastasios Chanalaris, A. M. N. Kabir, Paul A. Townsend, R. A. Mesquita, X. B. Cao, Mike Hubank, DS Latchman, M. Bellahcene, R.A. Knight, Anastasis Stephanou, Michael S. Marber, Kevin M. Lawrence
Publikováno v:
The FASEB Journal. 19:1-18
Urocortin (Ucn) is an endogenous cardioprotective agent that protects against the damaging effects of ischemia and reperfusion injury in vitro and in vivo. We have found that the mechanism of action of Ucn involves both acute activation of specific t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb33c0dae17cfe538b318639434dba31
https://doi.org/10.1096/fj.04-2506fje
https://doi.org/10.1096/fj.04-2506fje
Autor:
A Stephanou, DS Latchman
Publikováno v:
Current Genomics. 5:453-457
The signal transducers and activators of transcription (STATs) are a family of transcription factors which were originally identified on the basis of their ability to transduced a Signal From a cellular receptor into the nucleus and modulate the tran
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a3e643c0d5a3786549331ca1fd09e730
https://doi.org/10.2174/1389202043349066
https://doi.org/10.2174/1389202043349066
Publikováno v:
Biochemical and Biophysical Research Communications. 318:1045-1051
Brn-3a long and short isoforms are known to be encoded by two distinct mRNA transcripts derived from a single gene. Here we report that transcription of the two isoforms is differentially regulated. The short isoform has its own promoter, though many
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39f358b32b3842b805911b423757c0c2
https://doi.org/10.1016/j.bbrc.2004.04.134
https://doi.org/10.1016/j.bbrc.2004.04.134
Publikováno v:
Journal of Molecular and Cellular Cardiology. 35:257-264
Sensitive to apoptosis gene (SAG) is a novel RING finger protein that has been shown to be involved in protection against apoptotic cell death induced by oxidative stress in various cell types. As SAG has been previously shown to be expressed in the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cb498b9624cdfbbcdc3810ba2e35becc
https://doi.org/10.1016/s0022-2828(03)00003-8
https://doi.org/10.1016/s0022-2828(03)00003-8
Autor:
Andrew Tinker, DS Latchman, Laura Comini, Anastasios Chanalaris, Richard A. Knight, Paul A. Townsend, Mike Hubank, Kevin M. Lawrence, Anastasis Stephanou, Roberto Ferrari, Tiziano M. Scarabelli, Evasio Pasini
Publikováno v:
Circulation. 106:1556-1562
Background— Urocortin is a novel cardioprotective agent that can protect cardiac myocytes from the damaging effects of ischemia/reperfusion both in culture and in the intact heart and is effective when given at reperfusion. Methods and Results— W
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::98819cfeae119a411b49249704795147
https://doi.org/10.1161/01.cir.0000028424.02525.ae
https://doi.org/10.1161/01.cir.0000028424.02525.ae