Zobrazeno 1 - 10
of 742
pro vyhledávání: '"DREADDs"'
Publikováno v:
Stress, Vol 27, Iss 1 (2024)
Chronic stress leads to hypofunction of the medial prefrontal cortex (mPFC), mechanisms of which remain to be determined. Enhanced activation of GABAergic of parvalbumin (PV) expressing interneurons (INs) is thought to play a role in stress-induced p
Externí odkaz:
https://doaj.org/article/744a67ef492c41d3b85a20eb793e09ea
Publikováno v:
BMC Anesthesiology, Vol 23, Iss 1, Pp 1-12 (2023)
Abstract Objectives General anesthesia results in a state of unconsciousness that is similar to sleep. In recent years, increasing evidence has reported that astrocytes play a crucial role in regulating sleep. However, whether astrocytes are involved
Externí odkaz:
https://doaj.org/article/9fadf8ea3f674c2ebc3c98e91ead0426
Autor:
Makiko Shimizu, Mitsuhiro Yoshimura, Kazuhiko Baba, Naofumi Ikeda, Yuki Nonaka, Takashi Maruyama, Tatsushi Onaka, Yoichi Ueta
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionWithin the realm of chemogenetics, a particular form of agonists targeting designer receptors exclusively activated by designer drugs (DREADDs) has emerged. Deschloroclozapine (DCZ), a recently introduced DREADDs agonist, demonstrates rem
Externí odkaz:
https://doaj.org/article/d9322fcd42b14fb0817aaa3e3fa3fac7
Autor:
Sarah Delcourte, Amel Bouloufa, Renaud Rovera, Cécile Bétry, Erika Abrial, Ouria Dkhissi-Benyahya, Christophe Heinrich, Guillaume Marcy, Olivier Raineteau, Nasser Haddjeri, Guillaume Lucas, Adeline Etiévant
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 166, Iss , Pp 115384- (2023)
Prefrontal cortex (PFC) inputs to the hippocampus are supposed to be critical in memory processes. Astrocytes are involved in several brain functions, such as homeostasis, neurotransmission, synaptogenesis. However, their role in PFC-mediated modulat
Externí odkaz:
https://doaj.org/article/c470277b3f9d49139288122f37869c11
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Astrocytes are the major glial cell type in the central nervous system (CNS). Initially regarded as supportive cells, it is now recognized that this highly heterogeneous cell population is an indispensable modulator of brain development and function.
Externí odkaz:
https://doaj.org/article/67188e91bb8d4bddb02281b42f5d6c0a
Autor:
Ignasi Melchor-Eixea, Julian Guarque-Chabrera, Aitor Sanchez-Hernandez, Patricia Ibáñez-Marín, Raúl Pastor, Marta Miquel
Publikováno v:
Frontiers in Systems Neuroscience, Vol 17 (2023)
Substance Use Disorder (SUD) involves emotional, cognitive, and motivational dysfunction. Long-lasting molecular and structural changes in brain regions functionally and anatomically linked to the cerebellum, such as the prefrontal cortex, amygdala,
Externí odkaz:
https://doaj.org/article/31a714f690164852b2766f461e1c0d51
Publikováno v:
Brain Sciences, Vol 14, Iss 1, p 105 (2024)
Transcranial direct current stimulation (tDCS) is acknowledged for its non-invasive modulation of neuronal activity in psychiatric disorders. However, its application in insomnia research yields varied outcomes depending on different tDCS types and p
Externí odkaz:
https://doaj.org/article/16a6bbb790f942abb3f91e2184208180
Akademický článek
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Akademický článek
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Publikováno v:
Molecular Brain, Vol 15, Iss 1, Pp 1-14 (2022)
Abstract Self-grooming plays an essential role in hygiene maintenance, thermoregulation, and stress response. However, the neural populations involved in self-grooming remain largely unknown. The paraventricular hypothalamic nucleus (PVH) has been im
Externí odkaz:
https://doaj.org/article/a2ea85baf3324f4eadae8dbeb68eba73