Zobrazeno 1 - 10
of 40
pro vyhledávání: '"DPP4, dipeptidyl peptidase 4"'
Publikováno v:
Frontiers in Endocrinology, Vol 12 (2022)
Externí odkaz:
https://doaj.org/article/55905f66351546319b7be68f1f5c5d2a
Autor:
Chintan Shah, Young-Rock Hong, Rohit Bishnoi, Azka Ali, William Paul Skelton, Long H. Dang, Jinhai Huo, Nam H. Dang
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
Background: Dipeptidyl peptidase-4 (DPP4), a cell surface protein, exhibits a crucial role in tumor biology and regulation of the immune system. We aim to study the impact of DPP4 inhibitors (DPP4i) in patients with prostate cancer (PRC), pancreatic
Externí odkaz:
https://doaj.org/article/2f3be9ac5ba84f3d8a3b514e8494974e
Akademický článek
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Autor:
Deborah Pushparajah, Salma Jimenez, Shirley Wong, Hibah Alattas, Roderick A. Slavcev, Nafiseh Nafissi
Publikováno v:
Advanced Drug Delivery Reviews
The novel betacoronavirus, SARS-CoV-2 (severe acute respiratory syndrome coronavirus 2), has spread across the globe at an unprecedented rate since its first emergence in Wuhan City, China in December 2019. Scientific communities around the world hav
Publikováno v:
Vaccine
Middle East respiratory syndrome (MERS) is a threat to public health worldwide. A vaccine against the causative agent of MERS, MERS-coronavirus (MERS-CoV), is urgently needed. We previously identified a peptide ligand, Co4B, which can enhance antigen
Autor:
Naomi E. Apostolaki, Antonis S. Manolis, Helen Melita, Theodora A. Manolis, Antonis A. Manolis
Publikováno v:
Obesity Research & Clinical Practice
During the course of the COVID-19 pandemic, obesity has been shown to be an independent risk factor for high morbidity and mortality. Obesity confers poor outcomes in younger (
Autor:
Shomoita Sayed
Publikováno v:
Primary Care Diabetes
Highlights • Epidemiological studies conclude diabetes to be a leading comorbidity of COVID-19. • ACE2 polymorphisms in host can influence SARS-CoV-2 susceptibility or resistance. • The in-silico data need to be corroborated with in-vivo result
Autor:
James E. Crowe, Qin Zhang, Jeffrey L. Franklin, Dennis K. Jeppesen, James N. Higginbotham, Robert J. Coffey
Publikováno v:
Gastroenterology
Autor:
Mohammad Ajmal Ali, Arun Bahadur Gurung, Mohammad Abul Farah, Joongku Lee, Khalid Mashay Al-Anazi
Publikováno v:
Journal of Infection and Public Health
Journal of Infection and Public Health, Vol 14, Iss 2, Pp 227-237 (2021)
Journal of Infection and Public Health, Vol 14, Iss 2, Pp 227-237 (2021)
Graphical abstract
Highlights • The research highlights a novel strategy to block SARS-CoV-2 entry into the host cell. • High-throughput virtual screening identifies ZINC33039472 as a small molecule with favourable drug-like properties. •
Highlights • The research highlights a novel strategy to block SARS-CoV-2 entry into the host cell. • High-throughput virtual screening identifies ZINC33039472 as a small molecule with favourable drug-like properties. •
Publikováno v:
Journal of Clinical Neuroscience
Ng Kee Kwong, K C, Mehta, P R, Shukla, G & Mehta, A R 2020, ' COVID-19, SARS and MERS: A neurological perspective ', Journal of Clinical Neuroscience . https://doi.org/10.1016/j.jocn.2020.04.124
Ng Kee Kwong, K C, Mehta, P R, Shukla, G & Mehta, A R 2020, ' COVID-19, SARS and MERS: A neurological perspective ', Journal of Clinical Neuroscience . https://doi.org/10.1016/j.jocn.2020.04.124
Highlights • COVID-19 is caused by a highly pathogenic coronavirus named “SARS-CoV-2”. • COVID-19 pathophysiology is primarily defined by acute respiratory illness. • Several studies have revealed a possible neurological component to COVID-