Zobrazeno 1 - 10
of 338
pro vyhledávání: '"DOYLE III, FRANCIS J."'
This work considers the problem of personalized dose guidance using Bayesian optimization that learns the optimum drug dose tailored to each individual, thus improving therapeutic outcomes. Safe learning using interior point method ensures patient sa
Externí odkaz:
http://arxiv.org/abs/2210.16944
This paper considers the problem of Bayesian optimization for systems with safety-critical constraints, where both the objective function and the constraints are unknown, but can be observed by querying the system. In safety-critical applications, qu
Externí odkaz:
http://arxiv.org/abs/2205.02327
Autor:
Ortmann, Lukas, Shi, Dawei, Dassau, Eyal, Doyle III, Francis J., Misgeld, Berno J. E., Leonhardt, Steffen
Publikováno v:
American Control Conference (ACC) 2019
The human insulin-glucose metabolism is a time-varying process, which is partly caused by the changing insulin sensitivity of the body. This insulin sensitivity follows a circadian rhythm and its effects should be anticipated by any automated insulin
Externí odkaz:
http://arxiv.org/abs/2101.11887
Autor:
Aiello, Eleonora M., Wolkowicz, Kelilah L., Pinsker, Jordan E., Dassau, Eyal, Doyle III, Francis J.
Publikováno v:
In Chemical Engineering Science 5 March 2023 267
Autor:
Ortmann, Lukas, Shi, Dawei, Dassau, Eyal, Doyle III, Francis J., Leonhardt, Steffen, Misgeld, Berno J. E.
Publikováno v:
Asian Control Conference (ASCC) 2017
The insulin sensitivity (IS) of the human body changes with a circadian rhythm. This adds to the time-varying feature of the glucose metabolism process and places challenges on the blood glucose (BG) control of patients with Type 1 Diabetes Mellitus.
Externí odkaz:
http://arxiv.org/abs/1707.09948
Autor:
Cescon, Marzia, Choudhary, Divya, Pinsker, Jordan E., Dadlani, Vikash, Church, Mei Mei, Kudva, Yogish C., Doyle III, Francis J., Dassau, Eyal
Publikováno v:
In Computers in Biology and Medicine August 2021 135
Autor:
Fushimi, Emilia, Aiello, Eleonora M., Cho, Sunghyun, Riddell, Michael C., Gal, Robin L., Martin, Corby K., Patton, Susana R., Rickels, Michael R., Doyle III, Francis J.
Publikováno v:
Diabetes Technology & Therapeutics; Oct2024, Vol. 26 Issue 10, p709-719, 11p
Autor:
Cho, Sunghyun, Aiello, Eleonora M., Ozaslan, Basak, Riddell, Michael C., Calhoun, Peter, Gal, Robin L., Doyle III, Francis J.
Publikováno v:
Journal of Diabetes Science & Technology; Sep2024, Vol. 18 Issue 5, p1146-1156, 11p
Akademický článek
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In the mammalian suprachiasmatic nucleus (SCN), a population of noisy cell-autonomous oscillators synchronizes to generate robust circadian rhythms at the organism-level. Within these cells two isoforms of Cryptochrome, Cry1 and Cry2, participate in
Externí odkaz:
http://arxiv.org/abs/1411.4624