Prenatal testosterone treatment alters LH and testosterone responsiveness to GnRH agonist in male sheep

Autor: SERGIO E RECABARREN, ALEJANDRO LOBOS, YARA FIGUEROA, VASANTHA PADMANABHAN, DOUGLAS L FOSTER, TERESA SIR-PETERMANN

Publikováno v: Biological Research, Vol 40, Iss 3, Pp 329-338 (2007)

Although evidence is accumulating that prenatal testosterone (T) compromises reproductive function in the female, the effects of excess T in utero on the postnatal development of male reproductive function has not been studied. The aim of this study

Externí odkaz: https://doaj.org/article/da3acd07584c404e815f7436e27e6b7d

Novel concepts about normal sexual differentiation of reproductive neuroendocrine function and the developmental origins of female reproductive dysfunction: the sheep model

Autor: Leslie M. Jackson, Douglas L. Foster, Vasantha Padmanabhan

Publikováno v: Bioscientifica Proceedings.

The neuroendocrine regulation of GnRH secretion plays a central role in timing gamete release in both sexes. This regulation is more complex in the female because the discontinuous release of ova is more complex than the continuous release of spermat

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dc7b4c38336bf6e554c893ea27e3d42
https://doi.org/10.1530/biosciprocs.6.006

Organizational Actions of Postnatal Estradiol in Female Sheep Treated Prenatally with Testosterone: Programming of Prepubertal Neuroendocrine Function and the Onset of Puberty

Autor: Leslie M. Jackson, Kathleen M. Timmer, Douglas L. Foster

Publikováno v: Endocrinology. 150:2317-2324

Prenatal testosterone (T) exposure defeminizes reproductive neuroendocrine function in female sheep, although the LH surge dysfunctions are initially less severe in gonadally intact females than in females subject to neonatal ovariectomy and estradio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66639641e1acff565bfd4f499598c338
https://doi.org/10.1210/en.2008-1307

Contributors

Autor: Kjersti M. Aagaard, David F. Albertini, Eugene D. Albrecht, Steven M. Anderson, William E. Armstrong, Richard J. Auchus, Susan P. Bagby, Jacques Balthazart, April K. Binder, Jeffrey D. Blaustein, S. Marc Breedlove, Paula J. Brunton, Jeeyeon Cha, Shawn L. Chavez, Paula E. Cohen, Gerard S. Conway, John F. Couse, Geert J. de Vries, Emily DeFranco, Francesco J. DeMayo, Sudhansu K. Dey, Juan M. Dominguez, Edward M. Eddy, Rafael A. Fissore, Loretta M. Flanagan-Cato, Harvey M. Florman, Nancy G. Forger, Douglas L. Foster, Stephen Franks, Jennifer R. Gardiner, Kathrin Gassei, George D. Giraud, Robert L. Goodman, Andrea C. Gore, David R. Grattan, Janet E. Hall, Kate Hardy, Frances J. Hayes, David Hazlerigg, Mark P. Hedger, Jon D. Hennebold, Allan E. Herbison, Sylvia C. Hewitt, Stanley M. Hileman, Barry T. Hinton, J. Kim Holloway, Elaine M. Hull, Joan S. Hunt, Mary Hunzicker-Dunn, E. Keith Inskeep, Thomas Jansson, Sherri L. Jones, Kenneth S. Korach, Michael J. Large, Jon E. Levine, Xiao-Feng Li, Hyunjung (Jade) Lim, Mark Lindgren, Zhilin Liu, Joseph S. Lonstein, Paul S. MacLean, Catherine A. Marler, Kelly Mayo, Erik C. Mazur, Craig A. McArdle, Margaret M. McCarthy, Neil J. McKenna, James L. McManaman, Sam Mesiano, Joan I. Morrell, Louis J. Muglia, Makoto C. Nagano, Margaret C. Neville, Kevin T. O’Byrne, Peter O’Shaughnessy, Kyle E. Orwig, Stephanie A. Pangas, Gerald J. Pepe, Mariana Pereira, Margaret G. Petroff, James G. Pfaus, Bart T. Phillips, Tony M. Plant, Vincent Prevot, Gail S. Prins, Aleksandar Rajkovic, Cyril Ramathal, Renee A. Reijo Pera, JoAnne S. Richards, Emilie F. Rissman, Bernard Robaire, Mark S. Roberson, Sarah A. Robertson, John A. Russell, Yoel Sadovsky, Masayuki Shimada, Valerie Simonneaux, Lee B. Smith, Richard L. Stouffer, Susan S. Suarez, Melissa A. Suter, Amanda Swain, Manuel Tena-Sempere, Ei Terasawa, Kent L. Thornburg, Paul Le Tissier, Kiyotaka Toshimori, Hanna Valli, William H. Walker, Wipawee Winuthayanon, Selma Feldman Witchel, Larry J. Young, Anthony J. Zeleznik

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8bbc88bdd763759d49c6892a395595c8
https://doi.org/10.1016/b978-0-12-397175-3.01002-4

Long-Term Exposure of Female Sheep to Physiologic Concentrations of Estradiol: Effects on the Onset and Maintenance of Reproductive Function, Pregnancy, and Social Development in Female Offspring1

Autor: Leslie M. Jackson, Karl D. Malcolm, Christine Bergeon, Douglas L. Foster, Vasantha Padmanabhan, Theresa M. Lee

Publikováno v: Biology of Reproduction. 75:844-852

As steroids and steroid-like compounds accumulate in the environment, it has become important to understand how low-dose exposure affects reproductive function. Ovary-intact sheep were used in a multigenerational study, to determine whether chronic e

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8641389996add7287af6d0dcd301120c
https://doi.org/10.1095/biolreprod.106.053264