Zobrazeno 1 - 6
of 6
pro vyhledávání: '"DORA CARRICO-MONIZ"'
Publikováno v:
Anticancer research. 42(6)
Due to the lack of early detection methods and effective treatments, pancreatic cancer has one of the lowest five-year survival rates among all cancers. We have previously identified novel isoprenylated coumarin compounds that exhibit preferential cy
Autor:
Andrew C. Webb, Maria Jun, Hong Zhang, Dora Carrico-Moniz, Ronghao Zhou, Katherine W. Eyring, Alyssa F. Bacay
Publikováno v:
Journal of Cancer
Pancreatic cancer is one of the most devastating forms of human cancer. The lack of effective clinical treatments for pancreatic cancer has led to one of the lowest five-year survival rates among all cancers. Recently, our laboratory has developed a
Publikováno v:
Tetrahedron Letters. 56:1720-1723
Several derivatives of (1 S )-1,2-dihydro-1-naphthalenol (( S )- 7 ) have been synthesized and evaluated against human pancreatic adenocarcinoma cell line PANC-1 under nutrient-rich and nutrient-deprived conditions. The tert -butyldiphenylsilyl prote
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 24:4654-4658
A series of isoprenylated coumarins has been designed, synthesized, and evaluated against human pancreatic adenocarcinoma cell line PANC-1 under nutrient-rich and nutrient-deprived conditions. The compounds described investigate the effect of isopren
Publikováno v:
Analytical Biochemistry. 352:198-207
Fluorescent chemosensors of protein kinase activity provide a continuous, high-throughput sensing format for the study of the roles of these enzymes, which are crucial for regulating cellular function. Specifically, chemosensors using the nonnatural
Publikováno v:
Tetrahedron Letters. 52:3426-3428
The tertiary naphthoquinol is a key structural component of the antitumor natural products spiroxins A–E. Herein we report the first catalytic asymmetric approach to the tertiary naphthoquinol C4′ stereogenic center present in the spiroxin framew