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Akademický článek

Phosphatidylglycerol to Treat Chronic Skin Wounds in Diabetes

Autor: Yonghong Luo, Edymarie Vivaldi Marrero, Vivek Choudhary, Wendy B. Bollag

Publikováno v: Pharmaceutics, Vol 15, Iss 5, p 1497 (2023)

This review proposes the use of dioleoylphosphatidylglycerol (DOPG) to enhance diabetic wound healing. Initially, the characteristics of diabetic wounds are examined, focusing on the epidermis. Hyperglycemia accompanying diabetes results in enhanced

Externí odkaz: https://doaj.org/article/c7154b4d37da412bbdfc86578b01f44b

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Akademický článek

Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM

Autor: Carina Dargel, Friederike Gräbitz-Bräuer, Ramsia Geisler, Pascal Fandrich, Yvonne Hannappel, Lionel Porcar, Thomas Hellweg

Publikováno v: Molecules, Vol 26, Iss 16, p 4959 (2021)

Phosphatidylglycerols represent a large share of the lipids in the plasmamembrane of procaryotes. Therefore, this study investigates the role of charged lipids in the plasma membrane with respect to the interaction of the antiviral saponin glycyrrhiz

Externí odkaz: https://doaj.org/article/ff7e0da6e15a4d0993f23f18b1ae5392

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Akademický článek

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Stable DOPG/Glycyrrhizin Vesicles with a Wide Range of Mixing Ratios: Structure and Stability as Seen by Scattering Experiments and Cryo-TEM

Autor: Dargel, Carina, Gräbitz-Bräuer, Friederike, Geisler, Ramsia, Fandrich, Pascal, Hannappel, Yvonne, Porcar, Lionel, Hellweg, Thomas

Publikováno v: Molecules, Vol 26, Iss 4959, p 4959 (2021)
Molecules
Volume 26
Issue 16
'Molecules ', vol: 26, pages: 4959-1-4959-17 (2021)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::87d1695162b50c12d366a783d47cb554
https://www.mdpi.com/1420-3049/26/16/4959

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A promiscuous archaeal cardiolipin synthase enables construction of diverse natural and unnatural phospholipids

Autor: Ruben L. H. Andringa, Adriaan J. Minnaard, Marten Exterkate, Niels H. J. Wolbert, Niels A W de Kok, Arnold J. M. Driessen

Publikováno v: The Journal of Biological Chemistry, 296:100691. AMER SOC BIOCHEMISTRY MOLECULAR BIOLOGY INC
The Journal of Biological Chemistry

Cardiolipins (CL) are a class of lipids involved in the structural organization of membranes, enzyme functioning, and osmoregulation. Biosynthesis of CLs has been studied in eukaryotes and bacteria, but has been barely explored in archaea. Unlike the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19748282c2576fd1016b3a68ef4603df
https://hdl.handle.net/11370/338edff5-062f-40da-a1c5-617a8657e762

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Calcium mediated DNA binding in non-lamellar structures formed by DOPG/glycerol monooleate

Autor: José Teixeira, Daniela Uhríková, Juan Carlos Martínez, Lukáš Hubčík, Nina Kanjakova, Mária Klacsová, Alexander Búcsi, Sophie Combet

Publikováno v: Chemistry and Physics of Lipids
Chemistry and Physics of Lipids, 2021, 239, pp.105118
Chemistry and Physics of Lipids, Elsevier, 2021, 239, pp.105118
Chemistry and Physics of Lipids, Elsevier, 2021, 239, pp.105118. ⟨10.1016/j.chemphyslip.2021.105118⟩
Chemistry and Physics of Lipids, 2021, 239, pp.105118. ⟨10.1016/j.chemphyslip.2021.105118⟩

International audience; In order to test an encapsulation method of short fragmented DNA (~ 20-300 bp), we study the solubilisation in 150 mM solution of NaCl of a cubic phase formed by glycerol monooleate (GMO) with negatively charged dioleoylphosph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6fb0921e15693239be8ea226d1a58af9
https://pubmed.ncbi.nlm.nih.gov/34280362

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Hydrophobicity-tuned anion responsiveness underlies endosomolytic cargo delivery mediated by amphipathic vehicle peptides

Autor: Shuangshuang Ji, Hao Fei, Xiaolong Chen, Hanjie Liu, Ang Li

Publikováno v: The Journal of Biological Chemistry

Peptide conformation can change subject to environment cues. This concept also applies to many cationic amphipathic peptides (CAPs) known to have cell membrane lytic or penetrative activities. Well-conditioned CAPs can match the properties of the tar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11e5bcc1c77a58618c41d844f8e23287
https://doi.org/10.1016/j.jbc.2021.101364

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Akademický článek

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The influence of liposomal formulation on the incorporation and retention of PNA oligomers

Autor: Concetta Avitabile, Alessandra Romanelli, Antonella Accardo, Paola Ringhieri, Michele Saviano, Giancarlo Morelli

Publikováno v: Colloids and surfaces. B, Biointerfaces
145 (2016): 462–469. doi:10.1016/j.colsurfb.2016.05.034
info:cnr-pdr/source/autori:Ringhieri P.; Avitabile C.; Saviano M.; Morelli G.; Romanelli A.; Accardo A./titolo:The influence of liposomal formulation on the incorporation and retention of PNA oligomers/doi:10.1016%2Fj.colsurfb.2016.05.034/rivista:Colloids and surfaces. B, Biointerfaces (Print)/anno:2016/pagina_da:462/pagina_a:469/intervallo_pagine:462–469/volume:145

Liposomal formulations composed of phospholipids with different unsaturation degrees, head groups and at different cholesterol content have been tested for the encapsulation of Peptide Nucleic Acid (PNA) oligomers. The best loading capability (177 ?g

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a7a02d4e3bea59d8636092736e6a94d
https://doi.org/10.1016/j.colsurfb.2016.05.034

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