Zobrazeno 1 - 10
of 2 465
pro vyhledávání: '"DOPAMINERGIC SYSTEM"'
Publikováno v:
Fundamental Research, Vol 4, Iss 4, Pp 806-819 (2024)
In addition to the cardinal motor symptoms, pain is a major non-motor symptom of Parkinson's disease (PD). Neuroinflammation in the substantia nigra pars compacta and dorsal striatum is involved in neurodegeneration in PD. But the polarization of mic
Externí odkaz:
https://doaj.org/article/2ad383ffc61f4b5a90eb48541f11eb9d
Publikováno v:
Heliyon, Vol 10, Iss 12, Pp e33158- (2024)
Nicotine, the main compound in cigarettes, leads to smoking addiction. Nicotine acts on the limbic dopamine reward loop in the midbrain by binding to nicotinic acetylcholine receptors, promoting the release of dopamine, and resulting in a rewarding e
Externí odkaz:
https://doaj.org/article/e92e987d7533470fa62976dd8b70183a
Long-term Intracerebroventricular Administration of Ouabain Causes Motor Impairments in C57Bl/6 Mice
Autor:
Yulia A. Timoshina, Rogneda B. Kazanskaya, Vladislav A. Zavialov, Anna B. Volnova, Alexander V. Latanov, Tatiana N. Fedorova, Raul R. Gainetdinov, Alexander V. Lopachev
Publikováno v:
Анналы клинической и экспериментальной неврологии, Vol 17, Iss 4, Pp 40-51 (2023)
Introduction. Cardiac glycosides are natural ligands of Na+/K+-ATPase, which regulate its activity and signaling. Intracerebroventricular administration of ouabain has been previously shown to induce hyperlocomotion in C57Bl/6 mice via a decrease in
Externí odkaz:
https://doaj.org/article/3880a927326f4a77992a74e92be8f44e
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
The endocannabinoid system comprises highly versatile signaling functions within the nervous system. It is reported to modulate the release of several neurotransmitters, consequently affecting the activity of neuronal circuits. Investigations have hi
Externí odkaz:
https://doaj.org/article/92230dc93f38410aa7ae1963d141e289
Social Isolation Induces Changes in the Monoaminergic Signalling in the Rat Medial Prefrontal Cortex
Autor:
Vivien Csikós, Fanni Dóra, Tamás Láng, Luca Darai, Vivien Szendi, Attila Tóth, Melinda Cservenák, Arpád Dobolyi
Publikováno v:
Cells, Vol 13, Iss 12, p 1043 (2024)
(1) Background: The effects of short-term social isolation during adulthood have not yet been fully established in rats behaviourally, and not at all transcriptomically in the medial prefrontal cortex (mPFC). (2) Methods: We measured the behavioural
Externí odkaz:
https://doaj.org/article/0e9792e9ff954ed690a4469c86fc34b9
Autor:
Tomasz Sirek, Agata Sirek, Przemysław Borawski, Izabella Ryguła, Katarzyna Król-Jatręga, Marcin Opławski, Dariusz Boroń, Michał Chalcarz, Piotr Ossowski, Konrad Dziobek, Nikola Zmarzły, Kacper Boroń, Patrycja Mickiewicz, Beniamin Oskar Grabarek
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 12, p 6546 (2024)
This study aimed to assess the expression profile of messenger RNA (mRNA) and microRNA (miRNA) related to the dopaminergic system in five types of breast cancer in Polish women. Patients with five breast cancer subtypes were included in the study: lu
Externí odkaz:
https://doaj.org/article/6c5b16638f0b4694b8c33bcbc52b69a2
Autor:
Bruno P. Guiard, Guillaume Gotti
Publikováno v:
Molecules, Vol 29, Iss 2, p 496 (2024)
This review highlights the advantages of high-precision liquid chromatography with an electrochemical detector (HPLC-ECD) in detecting and quantifying biological samples obtained through intracerebral microdialysis, specifically the serotonergic and
Externí odkaz:
https://doaj.org/article/97c88055895c47799dc31fae03b03131
Akademický článek
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Akademický článek
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Autor:
Autumn Taylor, Amanda Nweke, Veniesha Vincent, Marvellous Oke, Praveen Kulkarni, Craig F. Ferris
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
IntroductionThe medical and recreational use of cannabis has increased in the United States. Its chronic use can have detrimental effects on the neurobiology of the brain—effects that are age-dependent. This was an exploratory study looking at the
Externí odkaz:
https://doaj.org/article/6bec4c6464834fe0b2496abffeae1113