Zobrazeno 1 - 10
of 386 556
pro vyhledávání: '"DONNA"'
Autor:
Eric M. Cockman, Vivek Narayan, Belinda Willard, Sumangala P. Shetty, Paul R. Copeland, Donna M. Driscoll
Publikováno v:
RNA Biology, Vol 16, Iss 12, Pp 1682-1696 (2024)
Selenoproteins are a unique class of proteins that contain the 21st amino acid, selenocysteine (Sec). Addition of Sec into a protein is achieved by recoding of the UGA stop codon. All 25 mammalian selenoprotein mRNAs possess a 3′ UTR stem-loop stru
Externí odkaz:
https://doaj.org/article/13e62b08d7d8470e88c3a2f0917b072a
Autor:
Suming Wang, Victor Zota, Melanie Y. Vincent, Donna Clossey, Jian Jenny Chen, Michael Cieslewicz, Randolph S. Watnick, James Mahoney, Jing Watnick
Publikováno v:
npj Precision Oncology, Vol 8, Iss 1, Pp 1-10 (2024)
Abstract Despite the development of cancer biomarkers and targeted therapies, most cancer patients do not have a specific biomarker directly associated with effective treatment options. We have developed VT1021 that induces the expression of thrombos
Externí odkaz:
https://doaj.org/article/0f96566457eb478681a046ba79ade1bd
Autor:
Tae-Yeon Eom, J. Eric Schmitt, Yiran Li, Christopher M. Davenport, Jeffrey Steinberg, Audrey Bonnan, Shahinur Alam, Young Sang Ryu, Leena Paul, Baranda S. Hansen, Khaled Khairy, Stephane Pelletier, Shondra M. Pruett-Miller, David R. Roalf, Raquel E. Gur, Beverly S. Emanuel, Donna M. McDonald-McGinn, Jesse N. Smith, Cai Li, Jason M. Christie, Paul A. Northcott, Stanislav S. Zakharenko
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Neurodevelopmental disorders are thought to arise from intrinsic brain abnormalities. Alternatively, they may arise from disrupted crosstalk among tissues. Here we show the local reduction of two vestibulo-cerebellar lobules, the parafloccul
Externí odkaz:
https://doaj.org/article/17fb65dc25454794b98e473b3b8f562c
SHIV remission in macaques with early treatment initiation and ultra long-lasting antiviral activity
Autor:
Michele B. Daly, Chuong Dinh, Angela Holder, Donna Rudolph, Susan Ruone, Alison Swaims-Kohlmeier, George Khalil, Sunita Sharma, James Mitchell, Jillian Condrey, Daniel Kim, Yi Pan, Kelly Curtis, Peter Williams, William Spreen, Walid Heneine, J. Gerardo García-Lerma
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Studies in SIV-infected macaques show that the virus reservoir is particularly refractory to conventional suppressive antiretroviral therapy (ART). We posit that optimized ART regimens designed to have robust penetration in tissue reservoirs
Externí odkaz:
https://doaj.org/article/4f90d82ee7bb4dc8b7f56f9adf3b9032
Autor:
Lydia Ziane-Chaouche, Antonella Raffo-Romero, Nawale Hajjaji, Firas Kobeissy, Donna Pinheiro, Soulaimane Aboulouard, Adeline Cozzani, Suman Mitra, Isabelle Fournier, Dasa Cizkova, Michel Salzet, Marie Duhamel
Publikováno v:
Cell Death and Disease, Vol 15, Iss 12, Pp 1-16 (2024)
Abstract Chimeric antigen receptor (CAR)-T-cell therapy has revolutionized cellular immunotherapy, demonstrating remarkable efficacy in hematological cancers. However, its application in solid tumors faces significant challenges, including limited T-
Externí odkaz:
https://doaj.org/article/05aeac0709be4a5ba789061c3074d13d
Autor:
Anjola Onifade, Samantha L. Quaife, David Holden, Donna Chung, Martin Birchall, Michael D. Peake, Muntzer Mughal, Daisy McInnerney
Publikováno v:
BMC Health Services Research, Vol 24, Iss 1, Pp 1-15 (2024)
Abstract Introduction Cancer multi-disciplinary team meetings (MDTM) assemble clinical experts to make diagnostic and treatment recommendations. MDTMs can take place in person, virtually, or in a hybrid format. Virtual and hybrid MDTMs have been in u
Externí odkaz:
https://doaj.org/article/f30712a45f17473997800b965c918277
Autor:
Lior Peri, Donna Matzov, Dominic R. Huxley, Alon Rainish, Fabrizio Fierro, Liel Sapir, Tara Pfeiffer, Lukas Waterloo, Harald Hübner, Yoav Peleg, Peter Gmeiner, Peter J. McCormick, Dorothee Weikert, Masha Y. Niv, Moran Shalev-Benami
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-15 (2024)
Abstract Bitter taste receptors (TAS2Rs), a subfamily of G-protein coupled receptors (GPCRs) expressed orally and extraorally, elicit signaling in response to a large set of tastants. Among 25 functional TAS2Rs encoded in the human genome, TAS2R14 is
Externí odkaz:
https://doaj.org/article/ffe236aefc0341b29447e20725da57e1
Autor:
Neal W. Dickert, Donna Spiegelman, Jennifer S. Blumenthal-Barby, Garth Graham, Steven Joffe, Jeremy M. Kahn, Nancy E. Kass, Scott Y. H. Kim, Meeta P. Kerlin, Aisha T. Langford, James V. Lavery, Daniel D. Matlock, Kathleen N. Fenton, George A. Mensah
Publikováno v:
Implementation Science, Vol 19, Iss 1, Pp 1-9 (2024)
Abstract Ethical issues arise in the context of implementation science that may differ from those encountered in other research settings. This report, developed out of a workshop convened by the Center for Translation Research and Implementation Scie
Externí odkaz:
https://doaj.org/article/aa7c767cf3f4444481997cbc7e048c67
Autor:
Vivian Hernandez-Trujillo, Mary Hart, Rose Marie Ramos, Lynda Mitchell, Alex Colon Moya, Dorothy Delarosa, Margie Lorenzi, Marcela Gieminiani, Donna D. Gardner
Publikováno v:
Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Inequity in asthma and COVID-19 outcomes and research among Hispanic or Latino individuals is well established. Patient centered outcomes research (PCOR) may help address these inequalities. This report describes the development,
Externí odkaz:
https://doaj.org/article/5593919887dd4b8bb2f093ff3b2eaade
Autor:
Alfonso Jiménez-Villar, Alexander Matteson, David Huang, Travis K. Redd, Donna Kim, Siyu Chen
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract We demonstrate a new tomographic imaging device for 2D cross-sectional and 3D volumetric images of the anterior eye segment. The optical system combines optical sectioning with a stereoscopic camera setup to determine the true spatial locati
Externí odkaz:
https://doaj.org/article/84610303648644c2b3acb339ed87594e