Zobrazeno 1 - 10
of 33
pro vyhledávání: '"DONALD E. RICHARDS"'
Autor:
Donald E. Richards
Publikováno v:
1996 Annual Conference Proceedings.
Autor:
Mark Toraason, Ingrid Heinroth-Hoffmann, Donald E. Richards, P. Hoffmann, H.E. Wey, Patty I. Mathias
Publikováno v:
Cardiovascular Research. 30:889-898
Objectives: The purpose of this study was to investigate the effects of prolonged arachidonic acid (AA) exposure on electrically induced fluctuations of cytosolic free Ca2+ concentration ([Ca2+]i) in cardiac myocytes and to identify intracellular bio
Publikováno v:
Proceedings of the National Academy of Sciences. 91:9881-9885
Ouabain-sensitive uncoupled Na+ efflux has been studied in human, pig, and rat red cells and in vesicles containing reconstituted kidney Na+/K+ pumps obtained from these same species. The red cells from the different species gave qualitatively simila
Autor:
D.G DeBord, Kenneth L. Cheever, Russell E. Savage, Tirmenstein Ma, Walter W. Weigel, Begley Kb, Donald E. Richards
Publikováno v:
Archives of Toxicology. 67:531-537
The metabolism of the reproductive and developmental toxicant bis(2-methoxyethyl)ether (diglyme) was studied in isolated rat hepatocytes and in the intact rat. Male Sprague-Dawley rats (190–220 g) were used in both studies. Hepatocytes, isolated by
Publikováno v:
Toxicology in vitro : an international journal published in association with BIBRA. 9(4)
The purpose of the present study was to examine whether cardiac actions of dichloromethane (DCM) in vivo correlate with in vitro alterations of Ca(2+) dynamics in cardiac myocytes. Electrically induced fluctuations of cytosolic free Ca(2+) concentrat
Autor:
Begley Kb, Kenneth L. Cheever, C. J. Eisenmann, Walter W. Weigel, F. B. Daniel, Donald E. Richards
Publikováno v:
Fundamental and Applied Toxicology. 16:567-575
An embryotoxic oral dose of bis(2-methoxyethyl) ether (DGDME), 3.73 mmol/kg body wt (500 mg/kg), administered on the 11th day of gestation to pregnant CD-1 mice was metabolized predominantly by O-demethylation to 2-(2-methoxyethoxy)ethanol with subse
Autor:
Kenneth L. Cheever, Russell E. Savage, Donald E. Richards, Terri F. Swearengin, Walter W. Weigel, D. Gayle DeBord, Karen B. Begley
Publikováno v:
Fundamental and Applied Toxicology. 14:273-283
The macromolecular binding of 4,4'-methylenebis(2-chloroaniline) (MOCA), a suspect human carcinogen, was studied in the adult male Sprague-Dawley rat after both oral and dermal administration. Rats were euthanized 1, 3, 7, 10, 14, and 29 days after a
Autor:
KENNETH L. CHEEVER, DONALD E. RICHARDS, WALTER W. WEIGEL, KAREN B. BEGLEY, D. GAYLE DEBORD, TERRI F. SWEARENGIN, RUSSELL E. SAVAGE
Publikováno v:
Toxicological Sciences. 14:273-283
Publikováno v:
In Vitro Cellular & Developmental Biology - Animal. 34:19-21
Publikováno v:
Toxicology and applied pharmacology. 146(1)
Industrial exposure and pharmaceutical use of antimony compounds have been linked to altered cardiovascular function and pathology. Antimony compounds induce hypotension, bradycardia, and cardiac arrhythmias, all of which can arise from aberrations i