Zobrazeno 1 - 10
of 190
pro vyhledávání: '"DOMINIK PAUL MODEST"'
Autor:
Isabella Lurje, Deniz Uluk, Sandra Pavicevic, Minh Duc Phan, Dennis Eurich, Uli Fehrenbach, Dominik Geisel, Timo Alexander Auer, Uwe Pelzer, Dominik Paul Modest, Nathanael Raschzok, Igor Maximilian Sauer, Wenzel Schöning, Frank Tacke, Johann Pratschke, Georg Lurje
Publikováno v:
Cancer Medicine, Vol 12, Iss 17, Pp 17569-17580 (2023)
Abstract Background Body composition alterations are frequent in patients with cancer or chronic liver disease, but their prognostic value remains unclear in many cancer entities. Objective We investigated the impact of disease aetiology and body com
Externí odkaz:
https://doaj.org/article/e612c31cf2d049a896f001361aaf2580
Autor:
Sebastian Knitter, Gregor Duwe, Anika Sophie Beierle, Sina Pesthy, Paul Viktor Ritschl, Karl Herbert Hillebrandt, Alexander Arnold, Thomas Malinka, Dominik Paul Modest, Marcus Bahra, Johann Pratschke, Igor Maximilian Sauer, Moritz Schmelzle, Andreas Andreou
Publikováno v:
Cancers, Vol 14, Iss 23, p 5992 (2022)
(1) Background: Sinusoidal obstruction syndrome (SOS) after oxaliplatin-based chemotherapy is associated with unfavorable outcomes after partial hepatectomy for colorectal liver metastases (CLM). Bevacizumab, a monoclonal antibody against vascular en
Externí odkaz:
https://doaj.org/article/62baf91937a347808fd5ca8c829e9133
Autor:
Ramin Raul Ossami Saidy, Elisa Wegener, Deniz Uluk, Luca Dittrich, Wenzel Schöning, Georg Lurje, Robert Öllinger, Dominik Paul Modest, Frank Tacke, Oliver Haase, Johann Pratschke, Dennis Eurich
Publikováno v:
Medicina, Vol 58, Iss 12, p 1755 (2022)
Background and Objectives: After liver transplantation (LT), long-term immunosuppression (IS) is essential. IS is associated with de novo malignancies, and the incidence of colorectal cancer (CRC) is increased in LT patients. We assessed course of di
Externí odkaz:
https://doaj.org/article/b1e127a80f70414a8d9defc26d598c8f
Autor:
Jana Käthe Striefler, Hanno Riess, Philipp Lohneis, Sven Bischoff, Annika Kurreck, Dominik Paul Modest, Marcus Bahra, Helmut Oettle, Marianne Sinn, Henrik Bläker, Carsten Denkert, Sebastian Stintzing, Bruno Valentin Sinn, Uwe Pelzer
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
BackgroundThe Mucin-family protein, MUC1, impacts on carcinogenesis and tumor invasion. We evaluated the impact of MUC1 expression on outcome in a cohort of 158 patients with resected pancreatic ductal adenocarcinomas (PDAC) in the CONKO-001 study (a
Externí odkaz:
https://doaj.org/article/c46c33f0aa6a4faeb2215126a5c9b5db
Autor:
Jörg Kumbrink, Lisa Bohlmann, Soulafa Mamlouk, Torben Redmer, Daniela Peilstöcker, Pan Li, Sylvie Lorenzen, Hana Algül, Stefan Kasper, Dirk Hempel, Florian Kaiser, Marlies Michl, Harald Bartsch, Jens Neumann, Frederick Klauschen, Michael von Bergwelt-Baildon, Dominik Paul Modest, Arndt Stahler, Sebastian Stintzing, Andreas Jung, Thomas Kirchner, Reinhold Schäfer, Volker Heinemann, Julian W. Holch
Publikováno v:
Cancers, Vol 14, Iss 15, p 3631 (2022)
Most metastatic colorectal cancer (mCRC) patients succumb to refractory disease due to secondary chemotherapy resistance. To elucidate the molecular changes associated with secondary resistance, we recruited 64 patients with mCRC and hepatic metastas
Externí odkaz:
https://doaj.org/article/ac551b05f43141138488488ec5ebd79f
Autor:
Sibylle Baechmann, Steffen Ormanns, Michael Haas, Stephan Kruger, Anna Remold, Dominik Paul Modest, Thomas Kirchner, Andreas Jung, Jens Werner, Volker Heinemann, Stefan Boeck
Publikováno v:
BMC Cancer, Vol 17, Iss 1, Pp 1-5 (2017)
Abstract Background Despite the introduction of novel effective treatment regimens like gemcitabine plus nab-paclitaxel and FOLFIRINOX, pancreatic ductal adenocarcinoma (PDAC) remains one of the most aggressive epithelial tumors. Among the genetic al
Externí odkaz:
https://doaj.org/article/fbf00841595b4747abbe0993468ea5c6
Autor:
Stephan Kruger, Marie-Louise Legenstein, Verena Rösgen, Michael Haas, Dominik Paul Modest, Christoph Benedikt Westphalen, Steffen Ormanns, Thomas Kirchner, Volker Heinemann, Stefan Holdenrieder, Stefan Boeck
Publikováno v:
OncoImmunology, Vol 6, Iss 5 (2017)
Up to now, the efficacy of programmed death protein 1/programmed death ligand 1 (PD-1/PD-L1) blockade in pancreatic cancer (PC) remains uncertain. Serum levels of soluble PD-1 and PD-L1 (sPD-1/sPD-L1) have been reported to be independent prognostic f
Externí odkaz:
https://doaj.org/article/9be2c4fe652649b1a13884204e9f8420
Autor:
Arndt Stahler, Beeke Hoppe, Il-Kang Na, Luisa Keilholz, Lothar Müller, Meinolf Karthaus, Stefan Fruehauf, Ullrich Graeven, Ludwig Fischer von Weikersthal, Eray Goekkurt, Stefan Kasper, Andreas Jay Kind, Annika Kurreck, Annabel Helga Sophie Alig, Swantje Held, Anke Reinacher-Schick, Volker Heinemann, David Horst, Armin Jarosch, Sebastian Stintzing, Tanja Trarbach, Dominik Paul Modest
Publikováno v:
Journal of Clinical Oncology. 41:2975-2987
PURPOSE Consensus molecular subtypes (CMSs) were evaluated as prognostic and predictive biomarkers of patients with RAS wild-type metastatic colorectal cancer (mCRC) receiving fluorouracil and folinic acid (FU/FA) with or without panitumumab (Pmab) a
Autor:
Volker Heinemann, Ulrich Mansmann, Dominik Paul Modest, Sebastian Stintzing, Donna Pauler Ankerst, Ruediger Paul Laubender, Clemens Giessen
Purpose: To evaluate progression-free survival (PFS) as a potential surrogate endpoint (SEP) for overall survival (OS) in metastatic colorectal cancer (mCRC) with a focus on applicability to trials containing targeted therapy with anti-VEGF- or anti-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a26c6883684fca5451405d8e3539eb6f
https://doi.org/10.1158/1078-0432.c.6521447.v1
https://doi.org/10.1158/1078-0432.c.6521447.v1
Autor:
Volker Heinemann, Ulrich Mansmann, Dominik Paul Modest, Sebastian Stintzing, Donna Pauler Ankerst, Ruediger Paul Laubender, Clemens Giessen
PDF file - 82k, Trials included in the analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20b3f283c91159698433bf1568ad8c74
https://doi.org/10.1158/1078-0432.22448645.v1
https://doi.org/10.1158/1078-0432.22448645.v1