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Akademický článek
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Antidepressant-like effect of guanosine involves activation of AMPA receptor and BDNF/TrkB signaling
Autor:
Yasmim de Oliveira Dalsenter, Morgana Moretti, Mauren K. Tavares, Priscila B. Rosa, Ana Lúcia S. Rodrigues, Daiane B. Fraga, Isabella A. Heinrich, Fernanda Neutzling Kaufmann, Luis E.B. Bettio, Vivian B. Neis, Andiara E. Freitas, Rodrigo B. Leal, Nicolle Platt, Isabel Werle, Axel Fogaça Rosado
Publikováno v:
Purinergic Signal
Guanosine is a purine nucleoside that has been shown to exhibit antidepressant effects, but the mechanisms underlying its effect are not well established. We investigated if the antidepressant-like effect induced by guanosine in the tail suspension t
Autor:
Motoaki Saito, Takaaki Aratake, Youichirou Higashi, Takahiro Shimizu, Shogo Shimizu, Yohei Shimizu, Masaki Yamamoto, Suo Zou, Yoshiki Nagao, Tomoya Hamada, Hideaki Ono
Publikováno v:
Neurourology and Urodynamics. 39:1687-1699
AIM Brain nitric oxide (NO) have been reported in regulation of the sympatho-adrenomedullary system, which can affect voiding and storage functions. Therefore, we investigated effects of intracerebroventricularly (icv) administered 3-(4-morpholinyl)s
Publikováno v:
J Neurosci
Microinjections of a glutamate AMPA antagonist (DNQX) in medial shell of nucleus accumbens (NAc) can cause either intense appetitive motivation (i.e., 'desire') or intense defensive motivation (i.e., 'dread'), depending on site along a flexible rostr
Publikováno v:
Biosensors
Volume 11
Issue 9
Biosensors, Vol 11, Iss 348, p 348 (2021)
Volume 11
Issue 9
Biosensors, Vol 11, Iss 348, p 348 (2021)
Electrically controlled drug delivery of neurochemicals and biomolecules from conducting polymer microelectrode coatings hold great potentials in dissecting neural circuit or treating neurological disorders with high spatial and temporal resolution.
Autor:
Huizi Li, Xiangzhang Lv, Zhixin Guo, Zhenyu Qi, Xiaochun Jiang, Yan-Hong Zhou, Jing-Quan Yu, Golam Jalal Ahammed
Publikováno v:
Plant, Cell & Environment. 42:3326-3339
Plant glutamate receptor-like (GLR) genes play important roles in plant development and immune response. However, the functions of GLRs in abiotic stress response remain unclear. Here we show that cold acclimation at 12°C induced the transcripts of
Autor:
Yoshimi Inagaki, Tatsuya Matsura, Yoshinori Kitagawa, Akihiro Otsuki, Takuma Omotani, Yosuke Horikoshi, Kazuhiro Nakaso, Masaki Morimoto, Hideyo Sato
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-13 (2019)
Post-septic neurological and psychiatric illness (PSNPI) including dementia and depression may be observed after sepsis. However, the etiology of PSNPI and therapeutic treatment of PSNPI are unclear. We show that glutamate produced from microglia thr
Several forms of endocannabinoid (eCB) signaling have been described in the dorsal lateral striatum (DLS), however most experimental protocols used to induce plasticity do not recapitulate the firing patterns of striatal-projecting pyramidal neurons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::54ab14b082a6b157303361cfe1eefe83
https://doi.org/10.1101/2020.10.21.348995
https://doi.org/10.1101/2020.10.21.348995
Autor:
Tatiana A Gudasheva, K N Koliasnikova, P. Yu. Povarnina, S. B. Seredenin, A.G. Alyaeva, O. N. Vorontsova
Publikováno v:
Doklady. Biochemistry and biophysics. 493(1)
Previously we have shown that the neuropeptide cycloprolylglycine is an endogenous positive modulator of AMPA receptors and assumed that the pharmacological effects of CPG are associated with the brain neurotrophic factor. In this paper, we have firs