Zobrazeno 1 - 10
of 23
pro vyhledávání: '"DNMT1, DNA methyltransferase 1"'
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 165-175 (2022)
Genes & Diseases
Genes & Diseases
The retinoblastoma gene product (pRb) is a chromatin-associated protein that can either suppress or promote activity of key regulators of tissue-specific differentiation. We found that twelve weeks after transfection of the exogenous active (ΔB/X an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d2add27adc064277f436a6cfb0c6eb
http://www.sciencedirect.com/science/article/pii/S235230422030132X
http://www.sciencedirect.com/science/article/pii/S235230422030132X
Autor:
Shuya Luo, Lichuan Bai, Guan Wang, Sitong Liu, Hui Wang, Qinghuan Xiao, Ke Ma, Tianyu Wang, Kuan Gao, Hongyue Liang, Mei Liu
Publikováno v:
Journal of Advanced Research
Journal of Advanced Research, Vol 29, Iss, Pp 23-32 (2021)
Journal of Advanced Research, Vol 29, Iss, Pp 23-32 (2021)
Graphical abstract Cholesterol reduces TMEM16A expression via DNMT1-mediated promoter methylation and directly inhibits channel activities. TMEM16A inhibition promotes endothelial angiogenesis.
Introduction Ca2+-activated Cl− channel TMEM16A i
Introduction Ca2+-activated Cl− channel TMEM16A i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c199e8fb29bfa734f960b1e2a8383f5
http://europepmc.org/articles/PMC8020148
http://europepmc.org/articles/PMC8020148
Autor:
Xiaohui Pan, Bo Yang, Hongjie Guo, Shuyuan Cheng, Xi Chen, Ling Ding, Qiaojun He, Wenxin Zhang
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 10, Iss 5, Pp 723-733 (2020)
Acta Pharmaceutica Sinica. B
Acta Pharmaceutica Sinica. B
Immunotherapy strategies targeting the programmed cell death ligand 1 (PD-L1)/programmed cell death 1 (PD-1) pathway in clinical treatments have achieved remarkable success in treating multiple types of cancer. However, owing to the heterogeneity of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1ca7b0479f6fea7a89a3e1eb06905c5
https://doi.org/10.1016/j.apsb.2019.09.006
https://doi.org/10.1016/j.apsb.2019.09.006
Autor:
Geir Bjørklund, Athanasia K. Georgiopoulou, Spyros P. Perlepes, Massimiliano Francesco Peana, Christos T. Chasapis
Publikováno v:
Journal of Inorganic Biochemistry
The recent pandemic caused by the novel coronavirus resulted in the greatest global health crisis since the Spanish flu pandemic of 1918. There is limited knowledge of whether SARS-CoV-2 is physically associated with human metalloproteins. Recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c0e34330aa38a50bc84ab3a6257962b
https://pubmed.ncbi.nlm.nih.gov/33813307
https://pubmed.ncbi.nlm.nih.gov/33813307
Autor:
Yiting Guan, Xiaoke Huang, Wei Tao, Li Huang, Qianqian Gao, Chao Zhang, Lijun Zhang, Le Zong, Ran Wei, Guoliang Lyu, Xuebin Zhang
Publikováno v:
The Journal of Biological Chemistry
DNA methylation shows complex correlations with gene expression, and the role of promoter hypermethylation in repressing gene transcription has been well addressed. Emerging evidence indicates that gene body methylation promotes transcription; howeve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d73ca5dbe5a7f2b583dccf861fe99871
https://doi.org/10.1016/j.jbc.2021.101195
https://doi.org/10.1016/j.jbc.2021.101195
Autor:
Isamu Kameshita, Yasunori Sugiyama
Publikováno v:
Biochemistry and Biophysics Reports
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 40-45 (2017)
Biochemistry and Biophysics Reports, Vol 11, Iss C, Pp 40-45 (2017)
Diverse biological events are regulated through protein phosphorylation mediated by protein kinases. Some of these protein kinases are known to be involved in the pathogenesis of various diseases. Although 518 protein kinase genes were identified in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3f5b283bbad69dae81fc2b25ceca05c8
http://europepmc.org/articles/PMC5614692
http://europepmc.org/articles/PMC5614692
Publikováno v:
DNA Repair
DNA-protein crosslinks (DPCs) are a specific type of DNA lesion consisting of a protein covalently and irreversibly bound to DNA, which arise after exposure to physical and chemical crosslinking agents. DPCs can be bulky and thereby pose a barrier to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::3e5438d87ad1b1061b50aef98e3fe56a
https://doi.org/10.1016/j.dnarep.2018.08.025
https://doi.org/10.1016/j.dnarep.2018.08.025
Autor:
Yunyi Yao, David A. Lawrence, Kevin Manley, Tapan K. Mondal, Qishan Lin, Rosemary Matala, Mohammad Nizam Uddin
Publikováno v:
Brain, Behavior, & Immunity-Health, Vol 4, Iss, Pp 100069-(2020)
Brain, Behavior, & Immunity-Health
Brain, Behavior, & Immunity-Health
Female and male mice of the BTBR T+Itpr3tf/J (BTBR) strain have behaviors that resemble autism spectrum disorder. In comparison to C57BL/6 (B6) mice, BTBR mice have elevated humoral immunity, in that they have naturally high serum IgG levels and gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe8e06129179d9dad1686c6011414859
https://doi.org/10.1016/j.bbih.2020.100069
https://doi.org/10.1016/j.bbih.2020.100069
Autor:
Mikhail I. Shtilman, Oxana V. Klimenko
Publikováno v:
Toxicology Reports
Toxicology Reports, Vol 6, Iss, Pp 186-192 (2019)
Toxicology Reports, Vol 6, Iss, Pp 186-192 (2019)
Graphical abstract
Highlights • Morphological and genetic changes of colorectal adenocarcinoma cells after treatment with complex of mix piR-30074 and miR-152 and PNVP carrier were obtained. • The combination mix of sncRNAs for the transform
Highlights • Morphological and genetic changes of colorectal adenocarcinoma cells after treatment with complex of mix piR-30074 and miR-152 and PNVP carrier were obtained. • The combination mix of sncRNAs for the transform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a8847ad90819be1ab52fce449f944c9
https://pubmed.ncbi.nlm.nih.gov/30899675
https://pubmed.ncbi.nlm.nih.gov/30899675
Publikováno v:
In Gene 2000 242(1):407-418