Zobrazeno 1 - 10
of 445
pro vyhledávání: '"DNA-methylation analysis"'
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-11 (2024)
Abstract Background Colorectal cancer is one of the most common cancers worldwide. DNA methylation sites may serve as a new gene signature for colorectal cancer diagnosis. The search for representative DNA methylation sites is urgently needed. This s
Externí odkaz:
https://doaj.org/article/11aabf9095484a33ba1fcc60a8bff9e5
Autor:
Yuki Tanaka, Yuri Nakanishi, Erina Furuhata, Ken-ichi Nakada, Rino Maruyama, Harukazu Suzuki, Takahiro Suzuki
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Familial platelet disorder with associated myeloid malignancies (FPDMM) is an autosomal dominant disease caused by heterozygous germline mutations in RUNX1. It is characterized by thrombocytopenia, platelet dysfunction, and a predisposition
Externí odkaz:
https://doaj.org/article/a8d345d8c8054bdaa2f92711c813a6b2
Autor:
Ewelina Pośpiech, Aleksandra Pisarek, Joanna Rudnicka, Rezvan Noroozi, Michał Boroń, Aleksander Masny, Bożena Wysocka, Kamila Migacz-Gruszka, Dagmara Lisman, Paulina Pruszkowska-Przybylska, Magdalena Kobus, Maria Szargut, Joanna Dowejko, Kamila Stanisz, Julia Zacharczuk, Piotr Zieliński, Aneta Sitek, Andrzej Ossowski, Magdalena Spólnicka, Wojciech Branicki
Publikováno v:
Clinical Epigenetics, Vol 15, Iss 1, Pp 1-16 (2023)
Abstract Background DNA methylation analysis has proven to be a powerful tool for age assessment. However, the implementation of epigenetic age prediction in diagnostics or routine forensic casework requires appropriate laboratory methods. In this st
Externí odkaz:
https://doaj.org/article/41ae9f2b68714fcf9f5be3f7a22490df
Autor:
Zijiao Li, Xiang Zhou, Danxi Liao, Ruolan Liu, Xia Zhao, Jing Wang, Qiu Zhong, Zhuo Zeng, Yizhi Peng, Yinling Tan, Zichen Yang
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
IntroductionPseudomonas aeruginosa (P.aeruginosa) is an important opportunistic pathogen with broad environmental adaptability and complex drug resistance. Single-molecule real-time (SMRT) sequencing technique has longer read-length sequences, more a
Externí odkaz:
https://doaj.org/article/9c55d4c5a6f14666b2d3fe318964d991
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.
K zobrazení výsledku je třeba se přihlásit.
Publikováno v:
Mathematical Biosciences and Engineering, Vol 18, Iss 6, Pp 8951-8961 (2021)
Proportion of cancerous cells in a tumor sample, known as "tumor purity", is a major source of confounding factor in cancer data analyses. Lots of computational methods are available for estimating tumor purity from different types of genomics data o
Externí odkaz:
https://doaj.org/article/40351e5ffa674548b5f05bd56ff7f17d
Autor:
Estelle Colin, Yannis Duffourd, Emilie Tisserant, Raissa Relator, Ange-Line Bruel, Frédéric Tran Mau-Them, Anne-Sophie Denommé-Pichon, Hana Safraou, Julian Delanne, Nolwenn Jean-Marçais, Boris Keren, Bertrand Isidor, Marie Vincent, Cyril Mignot, Delphine Heron, Alexandra Afenjar, Solveig Heide, Anne Faudet, Perrine Charles, Sylvie Odent, Yvan Herenger, Arthur Sorlin, Sébastien Moutton, Jennifer Kerkhof, Haley McConkey, Martin Chevarin, Charlotte Poë, Victor Couturier, Valentin Bourgeois, Patrick Callier, Anne Boland, Robert Olaso, Christophe Philippe, Bekim Sadikovic, Christel Thauvin-Robinet, Laurence Faivre, Jean-François Deleuze, Antonio Vitobello
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Purpose: Patients with rare or ultra-rare genetic diseases, which affect 350 million people worldwide, may experience a diagnostic odyssey. High-throughput sequencing leads to an etiological diagnosis in up to 50% of individuals with heterogeneous ne
Externí odkaz:
https://doaj.org/article/dc232e817b8e4d02a082ed5b52095a4f
Autor:
Jacob Gutierrez, Brett A. Davis, Kimberly A. Nevonen, Samantha Ward, Lucia Carbone, Cheryl L. Maslen
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Turner Syndrome (TS) is a rare cytogenetic disorder caused by the complete loss or structural variation of the second sex chromosome. The most common cause of early mortality in TS results from a high incidence of left-sided congenital heart defects,
Externí odkaz:
https://doaj.org/article/cae7f1ff621c41809080dbf7bd61798f