Zobrazeno 1 - 10 of 34 pro vyhledávání: '"DNA-Binding Proteins/physiology"'
1
mSWI/SNF promotes Polycomb repression both directly and through genome-wide redistribution
Autor: Antonina Hafner, Gerald R. Crabtree, Christopher M. Weber, Jacob G. Kirkland, Benjamin Z. Stanton, Alistair N. Boettiger, Simon M. G. Braun
Publikováno v: Nature Structural & Molecular Biology, Vol. 28, No 6 (2021) pp. 501-511
Nat Struct Mol Biol
The mammalian SWI/SNF complex, or BAF complex, has a conserved and direct role in antagonizing Polycomb-mediated repression. Yet, BAF also promotes repression by Polycomb in stem cells and cancer. How BAF both antagonizes and promotes Polycomb-mediat
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d553f63fe89284877c325a5813a60c66
https://archive-ouverte.unige.ch/unige:154515
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2
Functional Expression of the Na-K-2Cl Cotransporter NKCC2 in Mammalian Cells Fails to Confirm the Dominant-negative Effect of the AF Splice Variant*
Autor: Peter W. Flatman, Jenny K. Christie, Anke Hannemann
Publikováno v: The Journal of Biological Chemistry
Hannemann, A, Christie, J K & Flatman, P W 2009, ' Functional Expression of the Na-K-2Cl Cotransporter NKCC2 in Mammalian Cells Fails to Confirm the Dominant-negative Effect of the AF Splice Variant ', Journal of Biological Chemistry, vol. 284, no. 51, pp. 35348-35358 . https://doi.org/10.1074/jbc.M109.060004
The renal bumetanide-sensitive Na-K-2Cl cotransporter (NKCC2) is the major salt transport pathway in the apical membrane of the mammalian thick ascending limb. It is differentially spliced and the three major variants (A, B, and F) differ in their lo
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1d916ad53ec851237a12737ae426606
http://europepmc.org/articles/PMC2790964
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3
[Properties and biological roles of TET proteins during embryogenesis and in hematopoiesis]
Autor: Mahfoudhi, Emna, Secardin, Lise, Scourzic, Laurianne, Bernard, Olivier, Vainchenker, William, Plo, Isabelle
Publikováno v: médecine/sciences
médecine/sciences, EDP Sciences, 2015, 31 (3), pp.268-274. ⟨10.1051/medsci/20153103012⟩
International audience; DNA methylation is associated with a large number of biological processes and mainly concerns the cytosine methylation at position 5 (5-mC). An active demethylation mechanism was highlighted in 2009 following the discovery tha
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::45a5b08ea116011fb40df63c532a8adb
https://pubmed.ncbi.nlm.nih.gov/25855280
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4
Propriétés et rôles biologiques des protéines TET au cours du développement et de l’hématopoïèse
Autor: Isabelle Plo, Laurianne Scourzic, Emna Mahfoudhi, Olivier Bernard, Lise Secardin, William Vainchenker
Publikováno v: médecine/sciences
médecine/sciences, 2015, 31 (3), pp.268-274. ⟨10.1051/medsci/20153103012⟩
médecine/sciences, EDP Sciences, 2015, 31 (3), pp.268-274. ⟨10.1051/medsci/20153103012⟩
DNA methylation is associated with a large number of biological processes and mainly concerns the cytosine methylation at position 5 (5-mC). An active demethylation mechanism was highlighted in 2009 following the discovery that TET proteins were enzy
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f258ad96249662ede8ba6da2d6be8298
https://hal-riip.archives-ouvertes.fr/pasteur-02015397
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6
Mitochondria-independent induction of Fas-mediated apoptosis by MSSP
Autor: Ken-ichi Matsumoto, Jun Nomura, Hiroyoshi Ariga, Sanae M.M. Iguchi-Ariga
Publikováno v: Scopus-Elsevier
Fas-mediated apoptosis has been proposed to play an important role in homeostasis. Fas triggers apoptosis after stimulation by its ligand FasL or the Fas ligand agonist anti-Fas antibody through a mitochondria-dependent or -independent pathway, and M
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4b634672592556e06737515c41834e
http://hdl.handle.net/2115/53731
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7
BARD1 induces apoptosis by catalysing phosphorylation of p53 by DNA-damage response kinase
Autor: Irmgard Irminger-Finger, Anis Feki, Laetitia Cartier, Philip Berardi, Charles Edward Jefford, Jian-Yu Wu, Karl-Heinz Krause
Publikováno v: Oncogene, Vol. 24, No 23 (2005) pp. 3726-3736
Oncogene
The BRCA1-associated RING domain protein BARD1 acts with BRCA1 in double-strand break repair and ubiquitination. BARD1 plays a role as mediator of apoptosis by binding to and stabilizing p53, and BARD1-repressed cells are resistant to apoptosis. We t
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b62f0000da06f4dd52dcb11a408e4a6
https://doi.org/10.1038/sj.onc.1208491
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8
The Ccr4-Not Complex Independently Controls both Msn2-Dependent Transcriptional Activation—via a Newly Identified Glc7/Bud14 Type I Protein Phosphatase Module—and TFIID Promoter Distribution
Autor: Joris Winderickx, Martine A. Collart, Katarina Petrovic, Johnny Roosen, Elisabetta Cameroni, Michel Werner, Ivo Pedruzzi, Claudio De Virgilio, Nicole James, Eve Lenssen, Ruth Bisig, Frédérique Dubouloz, Laurent Jean Marie Maillet
Publikováno v: Molecular and Cellular Biology, Vol. 25, No 1 (2005) pp. 488-98
Molecular and Cellular Biology
Molecular and Cellular Biology, 2005, 25, pp.488-498. ⟨10.1128/MCB.25.1.488-498.2005⟩
Molecular and Cellular Biology, American Society for Microbiology, 2005, 25, pp.488-498. ⟨10.1128/MCB.25.1.488-498.2005⟩
International audience; The Ccr4-Not complex is a conserved global regulator of gene expression, which serves as a regulatory platform that senses and/or transmits nutrient and stress signals to various downstream effectors. Presumed effectors of thi
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9db4603a3319eb46b4040350e9091105
https://doi.org/10.1128/mcb.25.1.488-498.2005
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9
Fibroblast Growth Factor Receptor Signaling Promotes Radial Glial Identity and Interacts with Notch1 Signaling in Telencephalic Progenitors
Autor: Susana Vaz Nery, Nicholas Gaiano, Gord Fishell, Keejung Yoon, Freddy Radtke, Michael Rutlin
Publikováno v: The Journal of Neuroscience. 24:9497-9506
The Notch and fibroblast growth factor (FGF) pathways both regulate cell fate specification during mammalian neural development. We have shown previously that Notch1 activation in the murine forebrain promotes radial glial identity. This result, toge
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1d90ada8438fda00ff15bb6dc979e469
https://doi.org/10.1523/jneurosci.0993-04.2004
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10
Overexpression of the Zinc Finger Protein MZF1 Inhibits Hematopoietic Development from Embryonic Stem Cells: Correlation with Negative Regulation of CD34 and c-myb Promoter Activity
Autor: Cesare Peschle, Ida Casella, Paola Melotti, Danilo Perrotti, T Skorski, Bruno Calabretta
Publikováno v: Molecular and Cellular Biology. 15:6075-6087
Zinc finger genes encode proteins that act as transcription factors. The myeloid zinc finger 1 (MZF1) gene encodes a zinc finger protein with two DNA-binding domains that recognize two distinct consensus sequences, is preferentially expressed in hema
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7acc19163f23751eb6d9457a95f8306
https://doi.org/10.1128/mcb.15.11.6075
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