Zobrazeno 1 - 10
of 39
pro vyhledávání: '"DNA-Binding Proteins/genetics/metabolism"'
Autor:
Camilla Bellone, Jonathan Moss, Nicolas Toni, Denis Jabaudon, Christian Lüscher, Ilaria Vitali, Bruno Golding, Andres De la Rossa
Publikováno v:
Nature neuroscience
Nature Neuroscience
Nature Neuroscience, Vol. 16, No 2 (2013) pp. 193-200
Nature Neuroscience
Nature Neuroscience, Vol. 16, No 2 (2013) pp. 193-200
The molecular mechanisms that control how progenitors generate distinct subtypes of neurons, and how undifferentiated neurons acquire their specific identity during corticogenesis, are increasingly understood. However, whether postmitotic neurons can
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b784129b03e12b3ede6bd009279813
Autor:
Gonzalo Gómez-López, Ángela M. Valverde, Alejo Efeyan, M. Mar González-Barroso, Elena Lopez-Guadamillas, Eduardo Rial, Sonia Martinez, Joaquín Pastor, Marta Cañamero, Ana Ortega-Molina, James R. Bischoff, Maribel Muñoz-Martin, Manuel Serrano, Eduardo Romanos, Francisca Mulero
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
13 páginas, 7 figuras, 7 figuras suplementarias, 7 tablas suplementarias.-- et al.
Aging in worms and flies is regulated by the PI3K/Akt/Foxo pathway. Here we extend this paradigm to mammals. Ptentg mice carrying additional genomic copies of Pt
Aging in worms and flies is regulated by the PI3K/Akt/Foxo pathway. Here we extend this paradigm to mammals. Ptentg mice carrying additional genomic copies of Pt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d151eb2806c5da3245cfdf905d11031
Publikováno v:
Virology. 405(2):524-529
Epstein–Barr virus (EBV) is widely spread in the human population. EBV nuclear antigen 1 (EBNA1) is a transcription factor that activates viral genes and is necessary for viral replication and partitioning, which binds the EBV genome cooperatively.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3a22d089d7f8dbe687303635e879b83
Autor:
Harri Lempiäinen, Jörg Urban, Gustav Ammerer, David Shore, Aino Uotila, Robbie Loewith, Ilse Dohnal
Publikováno v:
Molecular cell, Vol. 33, No 6 (2009) pp. 704-16
Ribosome biogenesis drives cell growth, and the large transcriptional output underlying this process is tightly regulated. The Target of Rapamycin (TOR) kinase is part of a highly conserved signaling pathway linking nutritional and stress signals to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::351b7aa4b4edf0c03b0e9ab5f63d89cb
https://doi.org/10.1016/j.molcel.2009.01.034
https://doi.org/10.1016/j.molcel.2009.01.034
Autor:
Jacqueline H. Enzlin, Adebanke F. Fagbemi, Giuseppina Giglia-Mari, Wim Vermeulen, Stuart G. Clarkson, Lidija Staresincic, Audrey M. Gourdin, Isabelle Dunand-Sauthier, Orlando D. Schärer, Nils Wijgers
Publikováno v:
EMBO Journal
EMBO Journal, EMBO Press, 2009, 28 (8), pp.1111-1120. ⟨10.1038/emboj.2009.49⟩
EMBO Journal, Vol. 28, No 8 (2009) pp. 1111-1120
EMBO Journal, 28(8), 1111-1120. Wiley-Blackwell
EMBO Journal, EMBO Press, 2009, 28 (8), pp.1111-1120. ⟨10.1038/emboj.2009.49⟩
EMBO Journal, Vol. 28, No 8 (2009) pp. 1111-1120
EMBO Journal, 28(8), 1111-1120. Wiley-Blackwell
Nucleotide excision repair (NER) requires the coordinated sequential assembly and actions of the involved proteins at sites of DNA damage. Following damage recognition, dual incision 5' to the lesion by ERCC1-XPF and 3' to the lesion by XPG leads to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::272338a7bb4b863e64e94c3bd36259ba
https://doi.org/10.1038/emboj.2009.49
https://doi.org/10.1038/emboj.2009.49
Publikováno v:
Cytogenetic and Genome Research, 122 (3-4)
The Ku heterodimer is a DNA end-binding protein that promotes the non-homologous end joining (NHEJ) pathway of DNA double strand break (DSB) repair by recruiting the catalytic subunit of the DNA-dependent protein kinase (DNA-PKcs). Ku is also a norma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::201b773531baa4e0f8769c10b3b4b33f
https://doi.org/10.1159/000167819
https://doi.org/10.1159/000167819
Autor:
Shin Takeda, Ortrun Mittelsten Scheid, Ingo Hofmann, Takashi Araki, Karel J. Angelis, Zerihun Tadele, Kei-ichi Shibahara, Aline V. Probst, Dierk Scheel, Tesfaye Mengiste, Jerzy Paszkowski, Hidetaka Kaya
Publikováno v:
Takeda, Shin; Tadele, Zerihun; Hofmann, Ingo; Probst, Aline V.; Angelis, Karel J.; Kaya, Hidetaka; Araki, Takashi; Mengiste, Tesfaye; Scheid, Ortrun Mittelsten; Shibahara, Kei-ichi; Scheel, Dierk; Paszkowski, Jerzy (2004). BRU1, a novel link between responses to DNA damage and epigenetic gene silencing in Arabidopsis. Genes & development, 18(7), pp. 782-793. Cold Spring Harbor Laboratory Press 10.1101/gad.295404
Genes and Development, Vol. 18, No 7 (2004) pp. 782-93
Genes and Development, Vol. 18, No 7 (2004) pp. 782-93
DNA repair associated with DNA replication is important for the conservation of genomic sequence information, whereas reconstitution of chromatin after replication sustains epigenetic information. We have isolated and characterized mutations in the B
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f91efc7cba902b5512479b759edd3401
https://doi.org/10.1101/gad.295404
https://doi.org/10.1101/gad.295404
Autor:
Joerg F. Schlaak, Dominique Garcin, Daniel Kolakofsky, Laura Eve Strahle, Philippe Le Mercier
Publikováno v:
Journal of Virology, Vol. 77, No 14 (2003) pp. 7903-13
We have used cDNA arrays to compare the activation of various cellular genes in response to infection with Sendai viruses (SeV) that contain specific mutations. Three groups of cellular genes activated by mutant SeV infection, but not by wild-type Se
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84449209ea5eb56a11addb9308f7e8b2
https://doi.org/10.1128/jvi.77.14.7903-7913.2003
https://doi.org/10.1128/jvi.77.14.7903-7913.2003
Publikováno v:
mBio
mBio, 2014, 5 (5), pp.e01529-14. ⟨10.1128/mBio.01529-14⟩
mBio, American Society for Microbiology, 2014, 5 (5), pp.e01529-14. ⟨10.1128/mBio.01529-14⟩
mBio 5 (5), . (2014)
mBio, Vol 5, Iss 5 (2014)
mBio, 2014, 5 (5), pp.e01529-14. ⟨10.1128/mBio.01529-14⟩
mBio, American Society for Microbiology, 2014, 5 (5), pp.e01529-14. ⟨10.1128/mBio.01529-14⟩
mBio 5 (5), . (2014)
mBio, Vol 5, Iss 5 (2014)
The endosymbiotic bacteria of the genus Wolbachia are present in most insects and are maternally transmitted through the germline. Moreover, these intracellular bacteria exert antiviral activity against insect RNA viruses, as in Drosophila melanogast
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::34612dee7f4f9b0b75f7aa20198c81ea
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02192912
https://hal-univ-lyon1.archives-ouvertes.fr/hal-02192912
Autor:
Carlos Cordon-Cardo, Jiangwen Zhang, Riccardo Taulli, Xue-Song Liu, Winston Patrick Kuo, Zhenbang Chen, Kaitlyn A. Webster, David R. Shaffer, Yvonne Tay, Ainara Egia, Enrique Gonzalez-Billalabeitia, Brett S. Carver, Caterina Nardella, Andrea Lunardi, Sabina Signoretti, Pier Paolo Pandolfi, Ugo Ala, Guocan Wang, William L. Gerald
Publikováno v:
Nature genetics
Zbtb7a has previously been described as a powerful proto-oncogene. Here we unexpectedly demonstrate that Zbtb7a has a critical oncosuppressive role in the prostate. Prostate-specific inactivation of Zbtb7a leads to a marked acceleration of Pten loss-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b334f21c159e3b471e33a6bae4022ee
http://hdl.handle.net/2318/140793
http://hdl.handle.net/2318/140793