Zobrazeno 1 - 10
of 11
pro vyhledávání: '"DNA-Binding Proteins/deficiency"'
Autor:
Andrew L. Schwaderer, Vijay Saxena, Martina Tuttolomondo, Pernille Lund Hansen, Daniel M. Cohen, Ashley Rawson, Evan Barr-Beare, Edward J. Hollox, John Ketz, David S. Hains, Shamik Polley, John David Spencer, Henrik J. Ditzel, Samuel Arregui, Dong Liang, Ariel Cohen, Cinzia Casella
Publikováno v:
Clinical and Translational Medicine
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Hains, D S, Polley, S, Liang, D, Saxena, V, Arregui, S, Ketz, J, Barr-Beare, E, Rawson, A, Spencer, J D, Cohen, A, Hansen, P L, Tuttolomondo, M, Casella, C, Ditzel, H J, Cohen, D, Hollox, E J & Schwaderer, A L 2021, ' Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice ', Clinical and Translational Medicine, vol. 11, no. 7 . https://doi.org/10.1002/ctm2.477
Clinical and Translational Medicine, Vol 11, Iss 7, Pp n/a-n/a (2021)
Hains, D S, Polley, S, Liang, D, Saxena, V, Arregui, S, Ketz, J, Barr-Beare, E, Rawson, A, Spencer, J D, Cohen, A, Hansen, P L, Tuttolomondo, M, Casella, C, Ditzel, H J, Cohen, D, Hollox, E J & Schwaderer, A L 2021, ' Deleted in malignant brain tumor 1 genetic variation confers urinary tract infection risk in children and mice ', Clinical and Translational Medicine, vol. 11, no. 7 . https://doi.org/10.1002/ctm2.477
Autor:
Lee Mulderrig, Juan I. Garaycoechea
Publikováno v:
PLoS Genetics
PLoS Genetics, 16(4). Public Library of Science
PLoS Genetics, Vol 16, Iss 4, p e1008555 (2020)
PLoS Genetics, 16(4). Public Library of Science
PLoS Genetics, Vol 16, Iss 4, p e1008555 (2020)
Loss of the XPF-ERCC1 endonuclease causes a dramatic phenotype that results in progeroid features associated with liver, kidney and bone marrow dysfunction. As this nuclease is involved in multiple DNA repair transactions, it is plausible that this s
Autor:
Andrea M. Cooper, Manuela Flórido, António G. Castro, Margarida Borges, Mariana Resende, Ana R. Ribeiro, Marcos S. Cardoso, Nuno L. Alves, Rui Appelberg
Publikováno v:
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
IFN-gamma is known to be predominantly produced by lymphoid cells such as certain subsets of T cells, NK cells, and other group 1 innate lymphoid cells. In this study, we used IFN-gamma reporter mouse models to search for additional cells capable of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1fc258643b602938694e1a0a60f84973
Autor:
Sui Sui Dong, Jun Huang, Yiqun Deng, Hua Cai, Shirley M.-H. Sy, Junjie Chen, Enoch S.L. Yeung, Gabriel Tsz Mei Lok, Jun Jiang, Michael S.Y. Huen, Jun Wu
Publikováno v:
Journal of Biological Chemistry. 286:22355-22361
Histone ubiquitylation is emerging as an important protective component in cellular responses to DNA damage. The ubiquitin ligases RNF8 and RNF168 assemble ubiquitin chains onto histone molecules surrounding DNA breaks and facilitate retention of DNA
Autor:
Christine Hanselmann, Kaimin Chan, Susanne Braun, Marcus G. Gassmann, Christiane Born-Berclaz, Ulrich auf dem Keller, Sabine Werner, Yuet Wai Kan
Publikováno v:
Molecular and Cellular Biology. 22:5492-5505
Keratinocyte growth factor (KGF) is a potent mitogen for epithelial cells, and it promotes survival of these cells under stress conditions. In a search for KGF-regulated genes in keratinocytes, we identified the gene encoding the transcription factor
Publikováno v:
Oncogene
Oncogene, Nature Publishing Group, 2001, 20 (16), pp.1990--9. ⟨10.1038/sj.onc.1204262⟩
Oncogene, Nature Publishing Group, 2001, 20 (16), pp.1990--9. ⟨10.1038/sj.onc.1204262⟩
Ku antigen is necessary for DNA double-strand break (DSB) repair through its ability to bind DNA ends with high affinity and to recruit the catalytic subunit of DNA-PK to the DSBs. Ku-deficient cells are hypersensitive to agents causing DSBs in DNA b
Autor:
O. Meiniel, Walter Reith, Elsa Bonnafé, A. Meiniel, Dominique Baas, Carine Benadiba, Bénédicte Durand
Publikováno v:
European Journal of Neuroscience, Vol. 24, No 4 (2006) pp. 1020-1030
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2006, 24 (4), pp.1020-30. ⟨10.1111/j.1460-9568.2006.05002.x⟩
European Journal of Neuroscience
European Journal of Neuroscience, Wiley, 2006, 24 (4), pp.1020-30. ⟨10.1111/j.1460-9568.2006.05002.x⟩
Ciliated ependymal cells play central functions in the control of cerebrospinal fluid homeostasis in the mammalian brain, and defects in their differentiation or ciliated properties can lead to hydrocephalus. Regulatory factor X (RFX) transcription f
Autor:
Brice Petit, Denis Duboule, Pascal Gos, Tohru Kodama, Ueli Schibler, Philippe Fonjallaz, Mehdi Tafti, Francesca Damiola, Jozsef Zakany, Frédéric Gachon
Publikováno v:
Genes and Development, vol. 18, no. 12, pp. 1397-1412
DBP (albumin D-site-binding protein), HLF (hepatic leukemia factor), and TEF (thyrotroph embryonic factor) are the three members of the PAR bZip (proline and acidic amino acid-rich basic leucine zipper) transcription factor family. All three of these
Publikováno v:
Developmental Biology, Vol. 278, No 2 (2005) pp. 484-495
The differentiation of insulin-producing beta-cells has been investigated in great detail; however, little is known about the factors that delineate the second-most abundant endocrine lineage, the glucagon-producing alpha-cell. Here we utilize a nove
A basic leucine zipper transcription factor, NF-E2-related factor 2 (Nrf2), plays a critical role in the cellular defense mechanism by mediating a coordinate up-regulation of antioxidant responsive element-driven detoxification and antioxidant genes.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::492482dcc0746b117b1cc7cd51ed431f
http://hdl.handle.net/10722/49047
http://hdl.handle.net/10722/49047