Modernizing the Nonhomologous End-Joining Repertoire: Alternative and Classical NHEJ Share the Stage

Autor: Ludovic Deriano, David Roth

Publikováno v: Annual Review of Genetics
Annual Review of Genetics, 2013, 47 (1), pp.433-55. ⟨10.1146/annurev-genet-110711-155540⟩
Annual Review of Genetics, Annual Reviews, 2013, 47 (1), pp.433-55. ⟨10.1146/annurev-genet-110711-155540⟩

International audience; DNA double-strand breaks (DSBs) are common lesions that continually threaten genomic integrity. Failure to repair a DSB has deleterious consequences, including cell death. Misrepair is also fraught with danger, especially inap

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