Zobrazeno 1 - 10
of 201
pro vyhledávání: '"DNA vectors"'
Autor:
Christopher D. Thornton, Stuart Fielding, Kinga Karbowniczek, Alicia Roig-Merino, Alysha E. Burrows, Lorna M. FitzPatrick, Aseel Sharaireh, John P. Tite, Sara E. Mole, Richard P. Harbottle, Lisa J. Caproni, Tristan R. McKay
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss , Pp 348-358 (2021)
The application of induced pluripotent stem cells (iPSCs) in advanced therapies is increasing at pace, but concerns remain over their clinical safety profile. We report the first-ever application of doggybone DNA (dbDNA) vectors to generate human iPS
Externí odkaz:
https://doaj.org/article/0905fb3e8a9049a1a618396e833ec51d
Autor:
Iskra Sainova, Vera Kolyovska, Iliana Ilieva, Tzvetanka Markova, Dimitrina Dimitrova-Dikanarova, Radka Hadjiolova
Publikováno v:
Vaccines, Vol 11, Iss 7, p 1226 (2023)
The potential of viruses as appropriate vectors for the development of new therapeutic strategies, as well as for the design of molecular (DNA, RNA, and/or protein) vaccines via substitution of nucleotide sequences, has been proven. Among the most ap
Externí odkaz:
https://doaj.org/article/a44f033c7da84edc885479795627fe12
Autor:
Pei She Loh, Volker Patzel
Publikováno v:
Pharmaceutics, Vol 15, Iss 2, p 370 (2023)
Covalently closed dumbbell-shaped DNA delivery vectors comprising the double-stranded gene(s) of interest and single-stranded hairpin loops on both ends represent a safe, stable and efficacious alternative to viral and other non-viral DNA-based vecto
Externí odkaz:
https://doaj.org/article/d3ee932300ab4613a64b06273217fc31
Autor:
Mayra Colunga-Saucedo, Edson I. Rubio-Hernandez, Miguel A. Coronado-Ipiña, Sergio Rosales-Mendoza, Claudia G. Castillo, Mauricio Comas-Garcia
Publikováno v:
Viruses, Vol 15, Iss 1, p 132 (2022)
The genome of Alphaviruses can be modified to produce self-replicating RNAs and virus-like particles, which are useful virological tools. In this work, we generated three plasmids for the transfection of mammalian cells: an infectious clone of Chikun
Externí odkaz:
https://doaj.org/article/20595268616e47b694b52a5a280d5806
Autor:
Di Bonito P, Chiozzini C, Arenaccio C, Anticoli S, Manfredi F, Olivetta E, Ferrantelli F, Falcone E, Ruggieri A, Federico M
Publikováno v:
International Journal of Nanomedicine, Vol Volume 12, Pp 4579-4591 (2017)
Paola Di Bonito,1 Chiara Chiozzini,2 Claudia Arenaccio,2 Simona Anticoli,2 Francesco Manfredi,2 Eleonora Olivetta,2 Flavia Ferrantelli,2 Emiliana Falcone,3 Anna Ruggieri,3 Maurizio Federico2 1Department of Infectious, Parasitic and Immunomediated Dis
Externí odkaz:
https://doaj.org/article/22b57182a33d4ce9ad01c411d87d2985
Autor:
Hadjiolova, Iskra Sainova, Vera Kolyovska, Iliana Ilieva, Tzvetanka Markova, Dimitrina Dimitrova-Dikanarova, Radka
Publikováno v:
Vaccines; Volume 11; Issue 7; Pages: 1226
The potential of viruses as appropriate vectors for the development of new therapeutic strategies, as well as for the design of molecular (DNA, RNA, and/or protein) vaccines via substitution of nucleotide sequences, has been proven. Among the most ap
Autor:
Richard P. Harbottle, Aseel Sharaireh, Alicia Roig-Merino, Tristan R. McKay, Kinga Karbowniczek, Stuart Fielding, Alysha E. Burrows, Sara E. Mole, Lorna M. FitzPatrick, Christopher D. Thornton, John P. Tite, Lisa J. Caproni
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 23, Iss, Pp 348-358 (2021)
Molecular Therapy. Methods & Clinical Development
Molecular Therapy. Methods & Clinical Development
The application of induced pluripotent stem cells (iPSCs) in advanced therapies is increasing at pace, but concerns remain over their clinical safety profile. We report the first-ever application of doggybone DNA (dbDNA) vectors to generate human iPS
Akademický článek
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Autor:
Kenneth Lundstrom
Publikováno v:
Vaccines, Vol 7, Iss 1, p 29 (2019)
Alphaviruses have been engineered as vectors for high-level transgene expression. Originally, alphavirus-based vectors were applied as recombinant replication-deficient particles, subjected to expression studies in mammalian and non-mammalian cell li
Externí odkaz:
https://doaj.org/article/d42004aefd4340858405d28789d05b27
Akademický článek
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