Zobrazeno 1 - 10
of 133
pro vyhledávání: '"DNA repair mechanisms"'
Autor:
Yararbas Kanay, Sayar Ceyhan, Tavukcu Cemre, Korkmaz Taner, Çankaya Dilara Çakmak, Mutlu Elif Karabacak, Özbek Uğur
Publikováno v:
Türk Biyokimya Dergisi, Vol 49, Iss 5, Pp 698-702 (2024)
BLM, a member of the RecQ helicase family, plays an important role in DNA repair, and its biallelic mutations cause autosomal recessive Bloom syndrome, a disease characterized by elevated levels of sister chromatid exchange (SCE) in affected individu
Externí odkaz:
https://doaj.org/article/6f43f88d09cb45df933ec4d0c3b12e22
Autor:
Amirhossein Rismanbaf
Publikováno v:
Cancer Reports, Vol 7, Iss 1, Pp n/a-n/a (2024)
Abstract Background Conventional cancer treatments face the challenge of therapeutic resistance, which causes poor treatment outcomes. The use of combination therapies can improve treatment results in patients and is one of the solutions to overcome
Externí odkaz:
https://doaj.org/article/3b8ae19f4fae4c72ad353997daf00d6b
Nickel Increases Chromosomal Abnormalities by Interfering With the Initiation of DNA Repair Pathways
Publikováno v:
Iranian Journal of Toxicology, Vol 16, Iss 4, Pp 229-236 (2022)
Background: Nickel is a carcinogenic, heavy metal released through industrial activities and via natural resources. It is able to cause DNA damages by reducing the efficiency of DNA repair mechanisms. However, the exact time point at which it is able
Externí odkaz:
https://doaj.org/article/f96adfbcd89547a195ab750d8cf2cc40
Autor:
Jiawei Chen, Ravi Potlapalli, Heng Quan, Lingtao Chen, Ying Xie, Seyedamin Pouriyeh, Nazmus Sakib, Lichao Liu, Yixin Xie
Publikováno v:
BioTech, Vol 13, Iss 1, p 3 (2024)
DNA damage is a critical factor contributing to genetic alterations, directly affecting human health, including developing diseases such as cancer and age-related disorders. DNA repair mechanisms play a pivotal role in safeguarding genetic integrity
Externí odkaz:
https://doaj.org/article/37752d3d2b3f48f48b7462ee40a2152b
Publikováno v:
Radiology and Oncology, Vol 53, Iss 2, Pp 206-212 (2019)
Malignant mesothelioma (MM) is a rare aggressive tumour of mesothelium caused by asbestos exposure. It has been suggested that the genetic variability of proteins involved in DNA repair mechanisms affects the risk of MM. This study investigated the i
Externí odkaz:
https://doaj.org/article/c4229ba274fa45269b7c797081126f3f
Autor:
Javier E. Jiménez-Salazar, Rebeca Damian-Ferrara, Marcela Arteaga, Nikola Batina, Pablo Damián-Matsumura
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Estrogens have been implicated in the etiology of breast cancer for a long time. It has been stated that long-term exposure to estrogens is associated with a higher incidence of breast cancer, since estradiol (E2) stimulates breast cell growth; howev
Externí odkaz:
https://doaj.org/article/f02ac502c2c349d391d644c7466ae46a
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Over the past decade, the CRISPR-based genome editing technology has made a transformative impact on basic and applied biological research, revolutionizing various fields including medicine and agriculture. This survey paper provides a comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02060b9f3b44530f674094268589bfe5