Zobrazeno 1 - 10
of 1 848
pro vyhledávání: '"DNA repair genes"'
Autor:
Gaetano Pezzicoli, Federica Ciciriello, Vittoria Musci, Francesco Salonne, Anna Ragno, Mimma Rizzo
Publikováno v:
Current Oncology, Vol 30, Iss 10, Pp 9276-9290 (2023)
Clear cell renal cell carcinoma (ccRCC) treatment has undergone three major paradigm shifts in recent years, first with the introduction of molecular targeted therapies, then with immune checkpoint inhibitors, and, more recently, with immune-based co
Externí odkaz:
https://doaj.org/article/df6345a02e4b4435b1103bb7b4513ef5
Autor:
Maroua Boujemaa, Fatma Nouira, Nouha Jandoubi, Nesrine Mejri, Hanen Bouaziz, Cherine Charfeddine, Sonia Ben Nasr, Soumaya Labidi, Houda El Benna, Yosra Berrazega, Haifa Rachdi, Nouha Daoud, Farouk Benna, Abderrazek Haddaoui, Sonia Abdelhak, Mohamed Samir Boubaker, Hamouda Boussen, Yosr Hamdi
Publikováno v:
Frontiers in Genetics, Vol 15 (2024)
Introduction: Recent advances in sequencing technologies have significantly increased our capability to acquire large amounts of genetic data. However, the clinical relevance of the generated data continues to be challenging particularly with the ide
Externí odkaz:
https://doaj.org/article/753f3b5ce04d4ea383f28e4726b0729c
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 11, p 5995 (2024)
The incidence of thyroid cancer, one of the most common forms of endocrine cancer, is increasing rapidly worldwide in developed and developing countries. Various risk factors can increase susceptibility to thyroid cancer, but particular emphasis is p
Externí odkaz:
https://doaj.org/article/4b59d65064ce4769b6af96f02e7fa1fb
Autor:
Ismael C. Adolf, Linus P. Rweyemamu, Gokce Akan, Ted F. Mselle, Nazima Dharsee, Lucy A. Namkinga, Sylvester L. Lyantagaye, Fatmahan Atalar
Publikováno v:
Cancer Medicine, Vol 12, Iss 1, Pp 472-487 (2023)
Abstract Background Reproductive history and genetics are well‐known risk factors of breast cancer (BC). Little is known about how these factors interact to effect BC. This study investigated the association of ten polymorphisms in DNA repair genes
Externí odkaz:
https://doaj.org/article/04d4f4aef892441d8113539c4bfc120c
Autor:
Sandra D. Rshtuni, Galina E. Chernukha, Andrew E. Donnikov, Gyuzyal I. Tabeeva, Olga V. Burmenskaya, Larisa A. Marchenko
Publikováno v:
Гинекология, Vol 24, Iss 5, Pp 374-379 (2022)
Aim. To determine the incidence of premature ovarian failure (POF) and early menopause with regard to reproductive status in carriers of the pathogenic variant of the BRCA1 gene. Materials and methods. According to the inclusion and exclusion crit
Externí odkaz:
https://doaj.org/article/0ec7000a97b045fba13d11f517240882
Autor:
Mohammad Khan, Kaitlyn Hearn, Christian Parry, Mudasir Rashid, Hassan Brim, Hassan Ashktorab, Bernard Kwabi-Addo
Publikováno v:
Nutrients, Vol 16, Iss 1, p 114 (2023)
Prostate cancer is the most common cancer and the second leading cause of cancer deaths among men in the USA. Several studies have demonstrated the antitumor properties of saffron in different types of cancers, including prostate cancer. The oral adm
Externí odkaz:
https://doaj.org/article/21b88173a47842a19f55f72a807cde5b
Publikováno v:
Frontiers in Public Health, Vol 11 (2023)
IntroductionEpigenetic marks have been proposed as early changes, at the subcellular level, in disease development. To find more specific biomarkers of effect in occupational exposures to toxicants, DNA methylation studies in peripheral blood cells h
Externí odkaz:
https://doaj.org/article/f55a9259c89b4dca85546c8a4651daa9
Publikováno v:
Genes, Vol 14, Iss 10, p 1890 (2023)
Variants in non-homologous end joining (NHEJ) DNA repair genes are associated with various human syndromes, including microcephaly, growth delay, Fanconi anemia, and different hereditary cancers. However, very little has been done previously to syste
Externí odkaz:
https://doaj.org/article/1c63a074cebb4cefbbdf269754b2799b
Autor:
Karolina Seborova, Viktor Hlavac, Petr Holy, Sunniva S. Bjørklund, Thomas Fleischer, Lukas Rob, Martin Hruda, Jiri Bouda, Marcela Mrhalova, Mohammad Moufaq Khatar Al Obeed Allah, Pavel Vodicka, Ondrej Fiala, Pavel Soucek, Vessela N. Kristensen, Ludmila Vodickova, Radka Vaclavikova
Publikováno v:
Frontiers in Oncology, Vol 12 (2022)
Epithelial ovarian carcinoma (EOC) is known for high mortality due to diagnosis at advanced stages and frequent therapy resistance. Previous findings suggested that the DNA repair system is involved in the therapeutic response of cancer patients and
Externí odkaz:
https://doaj.org/article/4d3c2d1b733a4311bfac5bc44475ebba
Autor:
Abdelkader Heddar, Cagri Ogur, Sabrina Da Costa, Inès Braham, Line Billaud-Rist, Necati Findlinki, Claire Beneteau, Rachel Reynaud, Khaled Mahmoud, Stéphanie Legrand, Maud Marchand, Isabelle Cedrin-Durnerin, Adèle Cantalloube, Maeliss Peigne, Marion Bretault, Benedicte Dagher-Hayeck, Sandrine Perol, Celine Droumaguet, Sabri Cavkaytar, Carole Nicolas-Bonne, Hanen Elloumi, Mohamed Khrouf, Charlotte Rougier-LeMasle, Melanie Fradin, Elsa Le Boette, Perrine Luigi, Anne-Marie Guerrot, Emmanuelle Ginglinger, Amandine Zampa, Anais Fauconnier, Nathalie Auger, Françoise Paris, Elise Brischoux-Boucher, Christelle Cabrol, Aurore Brun, Laura Guyon, Melanie Berard, Axelle Riviere, Nicolas Gruchy, Sylvie Odent, Brigitte Gilbert-Dussardier, Bertrand Isidor, Juliette Piard, Laetitia Lambert, Samir Hamamah, Anne Marie Guedj, Aude Brac de la Perriere, Hervé Fernandez, Marie-Laure Raffin-Sanson, Michel Polak, Hélène Letur, Sylvie Epelboin, Genevieve Plu-Bureau, Sławomir Wołczyński, Sylvie Hieronimus, Kristiina Aittomaki, Sophie Catteau-Jonard, Micheline Misrahi
Publikováno v:
EBioMedicine, Vol 84, Iss , Pp 104246- (2022)
Summary: Background: Primary Ovarian Insufficiency (POI), a public health problem, affects 1-3.7% of women under 40 yielding infertility and a shorter lifespan. Most causes are unknown. Recently, genetic causes were identified, mostly in single famil
Externí odkaz:
https://doaj.org/article/617ed46466844b7380f9a8115b51a419