Zobrazeno 1 - 10
of 627
pro vyhledávání: '"DNA repair gene"'
Autor:
Yu-Hsuan Joni Shao, Cai-Sian Liao, Yu-Ching Hsu, Yu-Chiao Chiu, Tsai-Jung Lu, Yen-Chuan Ou, Tzu-Hung Hsiao
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-9 (2024)
Abstract Background Interpreting genetic variants remains a challenge in prostate cancer (PCa). Although many annotation tools are available for prioritizing causal variants, the clinical relevance of these variants is rarely studied. Methods We coll
Externí odkaz:
https://doaj.org/article/56510ca57fa740e5ab5ba6b5094cd84b
Autor:
Vittorio Fasulo, NicolòMaria Buffi, Giuseppe Chiarelli, Giovanni Lughezzani, Monica Zuradelli, Carla Barbara Ripamonti, Monica Barile, Paolo Bianchi, Alessio Benetti, Marco Paciotti, Alessandro Uleri, Pier Paolo Avolio, Alberto Saita, Rodolfo Hurle, Federica Maura, Luca Germagnoli, Rosanna Asselta, Giulia Soldà, Paolo Casale, Massimo Lazzeri
Publikováno v:
BJUI Compass, Vol 4, Iss 6, Pp 738-745 (2023)
Abstract Abstract Objective The aim of this study is to evaluate male awareness of developing prostate cancer (PCa) in families with germline DNA‐repair genes (DRG) variants. Materials and methods Data were collected from a prospective, monocentric
Externí odkaz:
https://doaj.org/article/b30c2e8d220847e08e10748f34ce0a6e
Autor:
Ehsan Zarei, Iraj Saadat
Publikováno v:
Egyptian Journal of Medical Human Genetics, Vol 24, Iss 1, Pp 1-7 (2023)
Abstract Background Cancer results from the accumulation of mutations in critical genes, such as DNA repair genes. But these genes are a double-edged sword, because the basis of current cancer treatment is DNA damage from chemotherapy and radiation,
Externí odkaz:
https://doaj.org/article/78cbeb75a5e54c62a0fbc47d2443f848
Akademický článek
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Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
DNA repair is a critical factor in tumor progression as it impacts tumor mutational burden, genome stability, PD-L1 expression, immunotherapy response, and tumor-infiltrating lymphocytes (TILs). In this study, we present a prognostic model for hepato
Externí odkaz:
https://doaj.org/article/b14a39ef805a42bbb0b90f2ff83a52e2
Autor:
Alpaslan Ozturk, Tugba Agbektas, Alakbar Huseynzada, Ruslan Guliyev, Rana Ganbarova, Ulviyya Hasanova, Ayca Tas, Sultan Erkan, Cemile Zontul, Nihal Inandiklioglu, Yavuz Silig
Publikováno v:
Life, Vol 13, Iss 10, p 1982 (2023)
We herein report the determination of the cytotoxic activity and expression profiles of some DNA repair genes of newly synthesized azomethines in the gastric cancer cell line (AGS). The studied novel compounds were synthesized by a condensation react
Externí odkaz:
https://doaj.org/article/f07b603814394c468b63ebeb5979dfa5
Publikováno v:
Zhongliu Fangzhi Yanjiu, Vol 48, Iss 7, Pp 704-708 (2021)
Objective To explore the value of DNA repair genes (DRGs) in predicting the effect of immunotherapy on lung adenocarcinoma based on second-generation sequencing technology. Methods The data of lung adenocarcinoma were obtained from the Cancer Genome
Externí odkaz:
https://doaj.org/article/f91d2f103aa44832884d47dbfcbebc10
Autor:
Binbin Yuan, Chengfei Jiang, Lingyan Chen, Lihui Wen, Jinlong Cui, Min Chen, Shu Zhang, Lin Zhou, Yimeng Cai, Jian-Hua Mao, Xiaoping Zou, Bo Hang, Pin Wang
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Gastric cancer is a heterogeneous group of diseases with only a fraction of patients responding to immunotherapy. The relationships between tumor DNA damage response, patient immune system and immunotherapy have recently attracted attention. Accumula
Externí odkaz:
https://doaj.org/article/d33ab475b4de429a8d50d0b9ee131a49
Akademický článek
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