Decoding protein dynamicity in DNA ligase activity through deep learning-based structural ensembles.

Autor: Mishra N; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037 USA., Callaghan S; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037 USA., Briney B; Department of Immunology and Microbiology, The Scripps Research Institute, La Jolla, CA 92037 USA.; Center for Viral Systems Biology, The Scripps Research Institute, La Jolla, CA 92037 USA.; Multi-Omics Vaccine Evaluation Consortium, The Scripps Research Institute, La Jolla, CA 92037 USA.; Scripps Consortium for HIV/AIDS Vaccine Development, The Scripps Research Institute, La Jolla, CA 92037 USA.; San Diego Center for AIDS Research, The Scripps Research Institute, La Jolla, CA 92037 USA.

Publikováno v: BioRxiv : the preprint server for biology [bioRxiv] 2024 Nov 07. Date of Electronic Publication: 2024 Nov 07.

Deficient DNA-Ligase Activity in the Metabolic Disease Tyrosinemia Type I

Autor: Prieto-Alamo, Maria Jose, Laval, Francoise

Publikováno v: Proceedings of the National Academy of Sciences of the United States of America, 1998 Oct . 95(21), 12614-12618.

Externí odkaz: https://www.jstor.org/stable/46107

Altered DNA ligase activity in human disease

Autor: Seema Khattri Bhandari, Tasmin Naila, Alan E. Tomkinson

Publikováno v: Mutagenesis

The joining of interruptions in the phosphodiester backbone of DNA is critical to maintain genome stability. These breaks, which are generated as part of normal DNA transactions, such as DNA replication, V(D)J recombination and meiotic recombination

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ee262aef5d5ef0fd2ae255a6068b7f6
https://doi.org/10.1093/mutage/gez026

A multiple primers-mediated exponential rolling circle amplification strategy for highly sensitive detection of T4 polynucleotide kinase and T4 DNA ligase activity

Autor: Wanling Cui, Xiaoyang Fan, Congcong Shen, Qingshuai Chen, Xiumei Zhang, Enguang Lv, Chonghui Li, Qiang Li, Rui Wang, Shicai Xu, Jihua Wang

Publikováno v: Microchemical Journal. 178:107403

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::672ae7b29e20eacc1156abd457a2c7eb
https://doi.org/10.1016/j.microc.2022.107403

Reduced DNA ligase activity in etoposide resistant human lymphatic leukaemia CEM cells

Autor: Fredriksson, Eva, Liliemark, Eva, Polischouk, Anya, Söderhäll, Stefan, Albertioni, Freidoun, Ljungquist, Siv

Publikováno v: In Biochemical Pharmacology 2002 63(2):259-264