Zobrazeno 1 - 10
of 1 151
pro vyhledávání: '"DNA immunization"'
Autor:
A. V. Zubkov, L. G. Butova, N. S. Kuzmina, I. V. Yakovleva, N. F. Gavrilova, A. A. Kornoukhova, A. V. Sidorov, B. V. Khraim Wael, V. V. Kuzmenko, I. V. Zubkova, V. V. Fadeev
Publikováno v:
Медицинская иммунология, Vol 26, Iss 5, Pp 941-952 (2024)
The number of patients with autoimmune thyroid diseases (Graves’disease, Hashimoto’sthyroiditis) is increasing globally. The most important part in the diagnosis of Graves’ disease (GD) is the detection of autoantibodies to the thyrotropin rece
Externí odkaz:
https://doaj.org/article/fd56513a04734bd889309a8996164c75
Autor:
Elie Richel, Jannik T. Wagner, Stephan Klessing, Riccardo Di Vincenzo, Vladimir Temchura, Klaus Überla
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
BackgroundFc-fusion proteins have been successfully developed for therapeutic purposes, but are also a promising platform for the fast generation and purification of immunogens capable of inducing strong humoral immune responses in preclinical immuni
Externí odkaz:
https://doaj.org/article/fa5e0200210546b9819e91d6c35e2062
Autor:
Olga V. Masalova, Ekaterina I. Lesnova, Sergey M. Andreev, Nadezhda N. Shershakova, Vyacheslav V. Kozlov, Kristina Yu. Permyakova, Natalia A. Demidova, Vladimir T. Valuev-Elliston, Evgeny A. Turetskiy, Alexander V. Ivanov, Tatyana N. Nikolaeva, Musa R. Khaitov, Alexander V. Pronin, Alla A. Kushch
Publikováno v:
Вопросы вирусологии, Vol 67, Iss 6, Pp 516-526 (2023)
Introduction. A vaccine against hepatitis C has not yet been developed. Recombinant proteins and plasmids encoding hepatitis C virus (HCV) proteins, the components of candidate vaccines, induce a weak immune response and require the use of adjuvants.
Externí odkaz:
https://doaj.org/article/33dcd894709e48829770ff1a2e04276a
Publikováno v:
The Journal of Poultry Science, Vol 60, Iss 2 (2023)
Immunization of egg-laying hens with viral antigens efficiently produces large amounts of virus-specific IgY antibodies from egg yolks. A supply of practical and economical antibodies against the rabies virus is being desired worldwide. We immunized
Externí odkaz:
https://doaj.org/article/8268c20e645347ec905dd7c1d74bbfc0
Publikováno v:
The Journal of Poultry Science, Vol 59, Iss 2, Pp 191-196 (2022)
DNA immunization has been used to study vaccination methods and for production of specific antibodies. The present study aimed to apply DNA immunization to prepare specific IgYs, which react against rabies virus N protein (RV-N) and can be used to re
Externí odkaz:
https://doaj.org/article/5339aab7f3bc46c3b4ed4936bbd3ae8d
Publikováno v:
Immuno, Vol 1, Iss 4, Pp 432-441 (2021)
To develop efficient applications of monoclonal antibodies for therapeutic purposes, stereospecific recognition of the target antigens is needed. DNA immunization is one of the best methods for sensitizing B lymphocytes that can produce conformation-
Externí odkaz:
https://doaj.org/article/caf5cc4f8cbf48cf84308aa3c9cfe9f3
Autor:
Olga V. Masalova, Ekaterina I. Lesnova, Vladimir A. Kalsin, Regina R. Klimova, Natalya E. Fedorova, Vyacheslav V. Kozlov, Natalya A. Demidova, Kirill I. Yurlov, Mikhail A. Konoplyannikov, Tatyana N. Nikolaeva, Alexander V. Pronin, Vladimir P. Baklaushev, Alla A. Kushch
Publikováno v:
Biology, Vol 12, Iss 6, p 792 (2023)
Hepatitis C virus (HCV) is one of the basic culprits behind chronic liver disease, which may result in cirrhosis and hepatocarcinoma. In spite of the extensive research conducted, a vaccine against HCV has not been yet created. We have obtained human
Externí odkaz:
https://doaj.org/article/e3dbee0b9f9149e29150dfe0d07b2420
Autor:
Hernan H. M. da Costa, Diego J. B. Orts, Andrew D. Moura, Amaro N. Duarte-Neto, Cinthya S. Cirqueira, Rodrigo A. Réssio, Cristina T. Kanamura, Karen Miguita, Jerenice E. Ferreira, Raimunda T. M. Santos, Patricia P. Adriani, Jair P. Cunha-Junior, Renato M. Astray, Regina M. Catarino, Marcelo Lancelotti, Carlos R. Prudencio
Publikováno v:
Viruses, Vol 15, Iss 2, p 555 (2023)
Neutralizing antibodies (nAbs) are a critical part of coronavirus disease 2019 (COVID-19) research as they are used to gain insight into the immune response to severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) infections. Among the
Externí odkaz:
https://doaj.org/article/211f38d354e44ef59f05a5951f99e2be
Autor:
Cristina W. Cunha, Katherine N. Baker, Donal O’Toole, Emily Cole, Smriti Shringi, Benjamin G. Dewals, Alain Vanderplasschen, Hong Li
Publikováno v:
Vaccines, Vol 10, Iss 12, p 2156 (2022)
Malignant catarrhal fever (MCF) is a complex and often fatal disease of ungulates. Effective vaccines are needed to avoid MCF outbreaks and mitigate losses. This study aimed to evaluate a sheep-associated MCF (SA-MCF) vaccine candidate targeting ovin
Externí odkaz:
https://doaj.org/article/d62739c662db402a8518bfc5537794d3
Autor:
Tatsuya Yamazaki, Mrityunjoy Biswas, Kouyu Kosugi, Maria Nagashima, Masanori Inui, Susumu Tomono, Hidekazu Takagi, Isao Ichimonji, Fumiaki Nagaoka, Akira Ainai, Hideki Hasegawa, Joe Chiba, Sachiko Akashi-Takamura
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Radioprotective 105 (RP105) (also termed CD180) is an orphan and unconventional Toll-like receptor (TLR) that lacks an intracellular signaling domain. The agonistic anti-RP105 monoclonal antibody (mAb) can cross-link RP105 on B cells, resulting in th
Externí odkaz:
https://doaj.org/article/349c2f98b4804ec392860fc398516433