Výsledky vyhledávání - "DNA copy number alterations"

Akademický článek

Association of FOSL1 copy number alteration and triple negative breast tumors

Autor: Leandro Tamião Rodrigues Serino, Tayana Schultz Jucoski, Stephanie Bath de Morais, Cíntia Callegari Coêlho Fernandes, Rubens Silveira de Lima, Cícero Andrade Urban, Luciane Regina Cavalli, Iglenir João Cavalli, Enilze Maria de Souza Fonseca Ribeiro

Publikováno v: Genetics and Molecular Biology, Vol 42, Iss 1, Pp 26-31 (2019)

Abstract Copy number alterations (CNAs) are a frequent feature in human breast cancer, and one of the hallmarks of genomic instability. The FOSL1, GSTP1 and CCND1 genes are located at 11q13, a cytoband commonly affected by CNA in breast cancer, with

Externí odkaz: https://doaj.org/article/1f6f1196658340fbbd5a904a5cd6d15a

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Akademický článek

Chromosome 9p copy number gains involving PD-L1 are associated with a specific proliferation and immune-modulating gene expression program active across major cancer types

Autor: Jan Budczies, Carsten Denkert, Balázs Győrffy, Peter Schirmacher, Albrecht Stenzinger

Publikováno v: BMC Medical Genomics, Vol 10, Iss 1, Pp 1-8 (2017)

Abstract Background Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients

Externí odkaz: https://doaj.org/article/d34c25e1b6b9400b83beb86ea0eebc2c

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Akademický článek

Recurrent patterns of DNA copy number alterations in tumors reflect metabolic selection pressures

Publikováno v: Molecular Systems Biology, Vol 13, Iss 2, Pp n/a-n/a (2017)

Abstract Copy number alteration (CNA) profiling of human tumors has revealed recurrent patterns of DNA amplifications and deletions across diverse cancer types. These patterns are suggestive of conserved selection pressures during tumor evolution but

Externí odkaz: https://doaj.org/article/ecca9cc2cad345a0a0b562644ca81d88

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Association of FOSL1 copy number alteration and triple negative breast tumors

Autor: Cicero Urban, Rubens Silveira de Lima, Luciane R. Cavalli, Enilze Maria de Souza Fonseca Ribeiro, Leandro Tamião Rodrigues Serino, Tayana Schultz Jucoski, Stephanie Bath de Morais, Cíntia Callegari Coêlho Fernandes, Iglenir J. Cavalli

Publikováno v: Genetics and Molecular Biology
Genetics and Molecular Biology v.42 n.1 2019
Sociedade Brasileira de Genética (SBG)
instacron:SBG
Genetics and Molecular Biology, Volume: 42, Issue: 1, Pages: 26-31, Published: 28 FEB 2019
Genetics and Molecular Biology, Vol 42, Iss 1, Pp 26-31 (2019)
Genetics and Molecular Biology, Issue: ahead, Published: 28 FEB 2019

Copy number alterations (CNAs) are a frequent feature in human breast cancer, and one of the hallmarks of genomic instability. The FOSL1, GSTP1 and CCND1 genes are located at 11q13, a cytoband commonly affected by CNA in breast cancer, with relevant

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12ba96da9d00609867c2fd21daafff0a
http://europepmc.org/articles/PMC6428133

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Genes co-amplified with ERBB2 or MET as novel potential cancer-promoting genes in gastric cancer

Autor: Young Kee Shin, Ryong Nam Kim, Jungsuk An, Mi Jeong Kwon, Kyoung Song, Sinyoung Jeon, Jinil Han, Jong-Sun Choi, Ensel Oh, Jonathan R. Pollack, Sungyoul Hong, Joo Seok Kim, Hae Min Jeong, Yoon-La Choi, Cheol-Keun Park

Publikováno v: Oncotarget

// Mi Jeong Kwon 1, 2, * , Ryong Nam Kim 3, 4, * , Kyoung Song 5 , Sinyoung Jeon 3 , Hae Min Jeong 3 , Joo Seok Kim 3 , Jinil Han 6 , Sungyoul Hong 3 , Ensel Oh 7 , Jong-Sun Choi 8 , Jungsuk An 9 , Jonathan R. Pollack 10 , Yoon-La Choi 7, 11, 12 , Ch

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0c9f50145d9dff179ffb44824bdf0805
http://europepmc.org/articles/PMC5696175

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DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up

Autor: Cinzia Castagnini, Francesco Giudici, Luca Messerini, Piero Dolara, Marilena Fazi, Cristina Luceri, Elisabetta Bigagli, Simona Toti, Francesco Acquadro, Francesco Tonelli, Carlotta De Filippo

Publikováno v: Cellulair oncology (2011. Print) 39 (2016): 545–558. doi:10.1007/s13402-016-0299-z
info:cnr-pdr/source/autori:Bigagli, Elisabetta; De Filippo, Carlotta; Castagnini, Cinzia; Toti, Simona; Acquadro, Francesco; Giudici, Francesco; Fazi, Marilena; Dolara, Piero; Messerini, Luca; Tonelli, Francesco; Luceri, Cristina/titolo:DNA copy number alterations, gene expression changes and disease-free survival in patients with colorectal cancer: a 10 year follow-up/doi:10.1007%2Fs13402-016-0299-z/rivista:Cellulair oncology (2011. Print)/anno:2016/pagina_da:545/pagina_a:558/intervallo_pagine:545–558/volume:39

Background: DNA copy number alterations (CNAs) and gene expression changes have amply been encountered in colorectal cancers (CRCs), but the extent at which CNAs affect gene expression, as well as their relevance for tumor development, are still poor

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cdf477420ac98385263d876f8c287198
https://doi.org/10.1007/s13402-016-0299-z

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An Integrated Approach for RNA-seq Data Normalization

Autor: Zhide Fang, Donald E. Mercante, Kun Zhang, Shengping Yang

Publikováno v: Cancer Informatics, Vol 2016, Iss 15, Pp 129-141 (2016)
Cancer Informatics
Cancer Informatics, Vol 15 (2016)

Background DNA copy number alteration is common in many cancers. Studies have shown that insertion or deletion of DNA sequences can directly alter gene expression, and significant correlation exists between DNA copy number and gene expression. Data n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c4bbd3babfb15491de9c8647ce1615fa
http://www.la-press.com/an-integrated-approach-for-rna-seq-data-normalization-article-a5723

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