Zobrazeno 1 - 10
of 244
pro vyhledávání: '"DNA Synthesis Inhibition"'
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1996 Apr . 93(8), 3199-3204.
Externí odkaz:
https://www.jstor.org/stable/38934
Autor:
Gülhan Turan-Zitouni, Leyla Yurttaş, Aouatef Tabbi, Gülşen Akalın Çiftçi, Halide Edip Temel, Zafer Asım Kaplancıklı
Publikováno v:
Molecules, Vol 23, Iss 1, p 135 (2018)
In this study, novel N′-(3-cyclohexyl/phenyl-4-(substituted phenyl)thiazole-2(3H)-ylidene)-2-[(5,6,7,8-tetrahydronaphthalen-2-yl)oxy]acetohydrazide (4a–4k) derivatives were synthesized and their anticancer potency were evaluated on human breast a
Externí odkaz:
https://doaj.org/article/c5bdc5e569974b1a8a4da68fe755944e
Publikováno v:
Journal of Cell Science. 134
Mammalian oocytes can be very long-lived cells and thereby are very likely to encounter DNA damage during their lifetime. Defective DNA repair may result in oocytes that are developmentally incompetent or give rise to progeny with congenital disorder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a43a6e4b4b37cbb3c4d5e798cbaa2a2
https://doi.org/10.1242/jcs.257774
https://doi.org/10.1242/jcs.257774
Autor:
Majumdar, S. K.
Publikováno v:
In Vitro Cellular & Developmental Biology, 1986 Jun 01. 22(6), 305-310.
Externí odkaz:
https://www.jstor.org/stable/4295920
Publikováno v:
Anti-cancer agents in medicinal chemistry. 22(9)
Background: Benzimidazole derivatives bearing pyridyl/pyrimidinyl piperazine moiety has attracted attention in medicinal chemistry and modern drug discovery since it exhibited a variety of biological activities, including anticancer activity. Objecti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3afea346179271c87d22257eb86cbf7
https://pubmed.ncbi.nlm.nih.gov/34238172
https://pubmed.ncbi.nlm.nih.gov/34238172
WOS: 000456470300003
PubMed ID: 29210665
Background: Arylidene indanones have attracted a great deal of interest due to their outstanding therapeutic applications. In particular, considerable research has pointed out the importance of aryli
PubMed ID: 29210665
Background: Arylidene indanones have attracted a great deal of interest due to their outstanding therapeutic applications. In particular, considerable research has pointed out the importance of aryli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ed7a7411e1d01da82fb03331883a18d
https://hdl.handle.net/11421/13580
https://hdl.handle.net/11421/13580
Publikováno v:
eLife, Vol 7 (2018)
eLife
eLife
DNA replication stress is often defined by the slowing or stalling of replication fork progression leading to local or global DNA synthesis inhibition. Failure to resolve replication stress in a timely manner contribute toward cell cycle defects, gen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a53e047784c7e85ab72007ef0a89b115
https://elifesciences.org/articles/41426
https://elifesciences.org/articles/41426
Publikováno v:
Koch, KS; Moran, T; Shier, WT; & Leffert, HL. (2018). High-Affinity Low-Capacity and Low-Affinity High-Capacity N-Acetyl-2-Aminofluorene (AAF) Macromolecular Binding Sites Are Revealed During the Growth Cycle of Adult Rat Hepatocytes in Primary Culture. TOXICOLOGICAL SCIENCES, 163(1), 26-35. doi: 10.1093/toxsci/kfy007. UC San Diego: Retrieved from: http://www.escholarship.org/uc/item/16j0s31d
Toxicological sciences : an official journal of the Society of Toxicology, vol 163, iss 1
Toxicological sciences : an official journal of the Society of Toxicology, vol 163, iss 1
Long-term cultures of primary adult rat hepatocytes were used to study the effects of N-acetyl-2-aminofluorene (AAF) on hepatocyte proliferation during the growth cycle; on the initiation of hepatocyte DNA synthesis in quiescent cultures; and, on hep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75d67646d3e50dbd782b5df12020ac8a
http://www.escholarship.org/uc/item/16j0s31d
http://www.escholarship.org/uc/item/16j0s31d
Autor:
Maria Nowaczek, Maria Podbielkowska
Publikováno v:
Acta Societatis Botanicorum Poloniae, Vol 48, Iss 3, Pp 355-363 (2015)
The action of cyclophosphamide on meristematic plant cells was checked. A mitostatic influence of this preparation was observed, by way of DNA synthesis inhibition. The disturbance in the course of mitosis is described and the characteristic changes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2fda881ef5d5c0007e2438160a93b4b
https://pbsociety.org.pl/journals/index.php/asbp/article/view/4817
https://pbsociety.org.pl/journals/index.php/asbp/article/view/4817
Autor:
Vadim V. Kachala, Zoya A. Starikova, I. K. Sviridova, S. I. Zykova, Yu. S. Nekrasov, Svetlana M. Peregudova, A. A. Simenel, N. S. Sergeeva, L. V. Snegur, M. M. Il’in
Publikováno v:
Russian Chemical Bulletin. 62:2056-2064
The structures, electrochemical properties, enantiomeric separation of ferrocenyl-(alkyl)pyrimidines and ferrocenyl(ethyl)adenine and their effects on the DNA synthesis in tumor cells were studied. Enantiomeric mixtures were separated by HPLC on modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bfe096df4e767a0d04730293e3aa45a5
https://doi.org/10.1007/s11172-013-0298-4
https://doi.org/10.1007/s11172-013-0298-4