Zobrazeno 1 - 10
of 170
pro vyhledávání: '"DNA Single Strand Break"'
Autor:
Szabo, Csaba, Virag, Laszlo, Cuzzocrea, Salvatore, Scott, Gwen S., Hake, Paul, O'Connor, Michael P., Zingarelli, Basilia, Salzman, Andrew, Kun, Ernest
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 1998 Mar . 95(7), 3867-3872.
Externí odkaz:
https://www.jstor.org/stable/44576
Autor:
Luther Davis, Nancy Maizels
Publikováno v:
Cell Reports, Vol 17, Iss 7, Pp 1872-1881 (2016)
Nicks are the most common form of DNA damage. The mechanisms of their repair are fundamental to genomic stability and of practical importance for genome engineering. We define two pathways that support homology-directed repair by single-stranded DNA
Externí odkaz:
https://doaj.org/article/f59be5967fe0473fac785ad5a48f7dbf
Autor:
Yuduki Someya, Sakine Kobayashi, Kazuya Toriumi, Shigeki Takeda, Noritaka Adachi, Aya Kurosawa
Publikováno v:
Genes
Volume 14
Issue 2
Pages: 420
Volume 14
Issue 2
Pages: 420
Natural antioxidants derived from plants exert various physiological effects, including antitumor effects. However, the molecular mechanisms of each natural antioxidant have not yet been fully elucidated. Identifying the targets of natural antioxidan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303ef5ca74251369e684f5f0790a719f
Autor:
William J. Nathan, Jennifer M. Colón-Mercado, Dali Zong, Kenta Shinoda, Michael E. Ward, Dongpeng Wang, Wei Wu, Maia Parsadanian, Raphael Souza Pavani, Peter J. McHugh, Seol Kyoung Jung, Steve Coon, Raffaella De Pace, Han-Yu Shih, Jacob Paiano, André Nussenzweig, Sarah E. Hill, Chongyi Chen, Solji Park, Rafael Casellas, Niek van Wietmarschen, Elsa Callen, Andres Canela, Keith W. Caldecott, Hana Hanzlikova
Publikováno v:
Nature
Defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons(1,2). The cellular genome is subjected to a constant barrage of endoge
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aa542e6d7406cb597c12b65a7f00f105
https://doi.org/10.1038/s41586-021-03468-5
https://doi.org/10.1038/s41586-021-03468-5
Akademický článek
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Publikováno v:
Neural Regeneration Research, Vol 16, Iss 1, Pp 110-112 (2021)
Neural Regeneration Research
Neural regeneration research 16(1), 110-(2021). doi:10.4103/1673-5374.286963
Neural Regeneration Research
Neural regeneration research 16(1), 110-(2021). doi:10.4103/1673-5374.286963
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9130eb108d179225227ff197a67bc46b
http://www.nrronline.org/article.asp?issn=1673-5374
http://www.nrronline.org/article.asp?issn=1673-5374
Autor:
Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han
Publikováno v:
EBioMedicine
Background DNA damage repair (DDR) alterations are important events in cancer initiation, progression, and therapeutic resistance. However, the involvement of DDR alterations in glioma malignancy needs further investigation. This study aims to charac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae288d30336e455721de6bf5436f314b
https://doi.org/10.1016/j.ebiom.2019.01.067
https://doi.org/10.1016/j.ebiom.2019.01.067
Autor:
Alexander Hergovich, Angeliki Ditsiou, Juan Jose Garcia-Gomez, Fumiko Esashi, Ramazan Gundogdu, Valenti Gomez, Victoria J. Spanswick, M. Kadir Erdogan, John A. Hartley
Publikováno v:
Cellular Signalling
Monopolar spindle-one binder (MOBs) proteins are evolutionarily conserved and contribute to various cellular signalling pathways. Recently, we reported that hMOB2 functions in preventing the accumulation of endogenous DNA damage and a subsequent p53/
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781e7f8fa05bb5c2814bf41145d35d64
https://aperta.ulakbim.gov.tr/record/232808
https://aperta.ulakbim.gov.tr/record/232808
Autor:
Dongpeng Wang, Elsa Callen, Steve Coon, Michael E. Ward, Keith W. Caldecott, Hana Hanzlikova, Maia Parsadanian, Han-Yu Shih, William J. Nathan, Peter J. McHugh, André Nussenzweig, Jennifer M. Colón-Mercado, Wei Wu, Jacob Paiano, Kenta Shinoda, Andres Canela, Raffaella De Pace, Sarah E. Hill
Genome stability is essential for all cell types. However, defects in DNA repair frequently lead to neurodevelopmental and neurodegenerative diseases, underscoring the particular importance of DNA repair in long-lived post-mitotic neurons. The neuron
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b8b70b8733f7cd95150d1d87107b8b4a
https://doi.org/10.1101/2020.12.16.423085
https://doi.org/10.1101/2020.12.16.423085
Publikováno v:
Genome Res
DNA single-strand breaks (SSBs), or “nicks,” are the most common form of DNA damage. Oxidative stress, endogenous enzyme activities, and other processes cause tens of thousands of nicks per cell per day. Accumulation of nicks, caused by high rate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7245d2d27b5182ca6b0b05be0fb0661
https://pubmed.ncbi.nlm.nih.gov/33355294
https://pubmed.ncbi.nlm.nih.gov/33355294