Zobrazeno 1 - 10
of 23
pro vyhledávání: '"DNA Replication/genetics"'
Autor:
Amandine Batté, Sophie C van der Horst, Mireille Tittel-Elmer, Su Ming Sun, Sushma Sharma, Jolanda van Leeuwen, Andrei Chabes, Haico van Attikum
Publikováno v:
Life Science Alliance, 5(4). LIFE SCIENCE ALLIANCE LLC
Life science alliance, vol. 5, no. 4, pp. e202101153
Life Science Alliance
Life Science Alliance, 5(4)
Life science alliance, vol. 5, no. 4, pp. e202101153
Life Science Alliance
Life Science Alliance, 5(4)
Chl1 helicase affects RPA-dependent checkpoint activation after replication fork arrest by ensuring proper dNTP levels, thereby controlling replication fork progression under stress conditions.
Eukaryotic cells have evolved a replication stress
Eukaryotic cells have evolved a replication stress
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d692bbaa302ffcdd800c03774c07b57
http://hdl.handle.net/1887/3564799
http://hdl.handle.net/1887/3564799
Autor:
Sébastien Rodrigue, Nicolas Rivard, Nicolas Carraro, Kévin T. Huguet, Romain Durand, Vincent Burrus
Publikováno v:
Nucleic acids research, vol. 49, no. 14, pp. 7807-7824
Nucleic Acids Research
Nucleic Acids Research
IncC conjugative plasmids and the multiple variants of Salmonella Genomic Island 1 (SGI1) are two functionally interacting families of mobile genetic elements commonly associated with multidrug resistance in the Gammaproteobacteria. SGI1 and its sibl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9f91b4705ae61cadd50ffc1dc0f45ea
https://serval.unil.ch/resource/serval:BIB_0F5DB3FD304D.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_0F5DB3FD304D.P001/REF.pdf
Autor:
Marion Blin, Caroline Brossas, Gaël A. Millot, Mélanie Schmidt, Viola Nähse, Marie-Noëlle Prioleau, Michelle Debatisse, Benoît Le Tallec
Publikováno v:
Nature Structural and Molecular Biology
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (1), pp.58-66. ⟨10.1038/s41594-018-0170-1⟩
Nature Structural and Molecular Biology, 2019, 26 (1), pp.58-66. ⟨10.1038/s41594-018-0170-1⟩
Nature Structural and Molecular Biology, Nature Publishing Group, 2019, 26 (1), pp.58-66. ⟨10.1038/s41594-018-0170-1⟩
Nature Structural and Molecular Biology, 2019, 26 (1), pp.58-66. ⟨10.1038/s41594-018-0170-1⟩
International audience; Common fragile sites (CFSs) are loci that are hypersensitive to replication stress and hotspots for chromosomal rearrangements in cancers. CFSs replicate late in S phase, are cell-type specific and nest in large genes. The rel
Autor:
Deegan, Tom D, Baxter, Jonathan, Ortiz Bazán, María Ángeles, Yeeles, Joseph T P, Labib, Karim P M
Publikováno v:
Deegan, T D, Baxter, J, Ortiz Bazán, M Á, Yeeles, J T P & Labib, K P M 2019, ' Pif1-Family Helicases Support Fork Convergence during DNA Replication Termination in Eukaryotes ', Molecular Cell, vol. 74, no. 2, pp. 231-244.e9 . https://doi.org/10.1016/j.molcel.2019.01.040
The convergence of two DNA replication forks creates unique problems during DNA replication termination. In E. coli and SV40, the release of torsional strain by type II topoisomerases is critical for converging replisomes to complete DNA synthesis, b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::ef5388d35615a0536df600e0f73ec0de
http://sro.sussex.ac.uk/id/eprint/84526/1/Deegan_et_al_2019.pdf
http://sro.sussex.ac.uk/id/eprint/84526/1/Deegan_et_al_2019.pdf
Autor:
Frandi, A., Collier, J.
Publikováno v:
Biochemical Society transactions, vol. 47, no. 1, pp. 187-196
The environmental Alphaproteobacterium Caulobacter crescentus is a classical model to study the regulation of the bacterial cell cycle. It divides asymmetrically, giving a stalked cell that immediately enters S phase and a swarmer cell that stays in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od______1900::3c79f056eff9429253d184160cbc6c3f
https://serval.unil.ch/notice/serval:BIB_8AE1B9583D91
https://serval.unil.ch/notice/serval:BIB_8AE1B9583D91
Autor:
Erik L. Miller, Simon M. G. Braun, Gerald R. Crabtree, Emma J. Chory, Cigall Kadoch, Robert T Williams, Joseph P Calarco, Christopher M. Weber, John L. Pulice
Publikováno v:
Nature Genetics, Vol. 49, No 2 (2017) pp. 213-222
Nature genetics
Nature genetics
The opposition between Polycomb repressive complexes (PRCs) and BAF (mSWI/SNF) complexes has a critical role in both development and disease. Mutations in the genes encoding BAF subunits contribute to more than 20% of human malignancies, yet the unde
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24d75515730584b4cfcebecce938e942
https://archive-ouverte.unige.ch/unige:154520
https://archive-ouverte.unige.ch/unige:154520
Autor:
Tobias Sahr, Clement Bertholet, Carmen Buchrieser, Christophe Rusniok, Raphaël Margueron, Serena Sanulli, Monica Rolando, Laura Gomez-Valero
Publikováno v:
Cell Host and Microbe
Cell Host and Microbe, Elsevier, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, Elsevier, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
Cell Host and Microbe, 2013, 13 (4), pp.395-405. ⟨10.1016/j.chom.2013.03.004⟩
International audience; Histone posttranslational modifications control eukaryotic gene expression and regulate many biological processes including immunity. Pathogens alter host epigenetic control to aid pathogenesis. We find that the intracellular
Autor:
Stela, McLachlan, Claudia, Giambartolomei, Jon, White, Pimphen, Charoen, Andrew, Wong, Chris, Finan, Jorgen, Engmann, Tina, Shah, Micha, Hersch, Clara, Podmore, Alana, Cavadino, Barbara J, Jefferis, Caroline E, Dale, Elina, Hypponen, Richard W, Morris, Juan P, Casas, Meena, Kumari, Yoav, Ben-Shlomo, Tom R, Gaunt, Fotios, Drenos, Claudia, Langenberg, Diana, Kuh, Mika, Kivimaki, Rico, Rueedi, Gerard, Waeber, Aroon D, Hingorani, Jacqueline F, Price, Ann P, Walker
Publikováno v:
PloS one, vol. 11, no. 6, pp. e0156914
PLoS ONE
PLoS ONE
Red blood cell (RBC) traits are routinely measured in clinical practice as important markers of health. Deviations from the physiological ranges are usually a sign of disease, although variation between healthy individuals also occurs, at least partl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::eccaa3539853e064387b65d53d977f91
https://serval.unil.ch/resource/serval:BIB_4A3C2460ABAA.P001/REF.pdf
https://serval.unil.ch/resource/serval:BIB_4A3C2460ABAA.P001/REF.pdf
Publikováno v:
The Journal of Cell Biology
The Journal of cell biology, vol. 212, no. 6, pp. 611-614
The Journal of cell biology, vol. 212, no. 6, pp. 611-614
In mitochondria, DNA replication, gene expression, and RNA degradation machineries coexist within a common nondelimited space, raising the question of how functional compartmentalization of gene expression is achieved. Here, we discuss the recently c
Publikováno v:
British Journal of Cancer
Mitochondrial DNA (mtDNA) content in ovarian carcinomas was assessed by quantitative PCR. Results show that mtDNA content in tumour cell was significantly higher than that in normal ovary. Change in mtDNA content was not related with patients' age or