Zobrazeno 1 - 10
of 52
pro vyhledávání: '"DNA Methylation Regulation"'
Autor:
Fangdong Li, Ruoheng Ge, Yanli Wang, Wei-Wei Deng, Wei Tong, Ali Inayat Mallano, Yeyun Li, En-Hua Xia, Qiong Wu, Ruopei Li, Jin Huang, Huijuan Zhao
Publikováno v:
The Plant Journal. 106:1312-1327
The tea plant (Camellia sinensis) is a thermophilic cash crop and contains a highly duplicated and repeat-rich genome. It is still unclear how DNA methylation regulates the evolution of duplicated genes and chilling stress in tea plants. We therefore
Autor:
Mikhail Ivanchenko, O. S. Vershinina, Maria Giulia Bacalini, Claudio Franceschi, Alexey Zaikin
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-12 (2021)
Scientific Reports
Scientific Reports
DNA methylation variability arises due to concurrent genetic and environmental influences. Each of them is a mixture of regular and noisy sources, whose relative contribution has not been satisfactorily understood yet. We conduct a systematic assessm
Publikováno v:
Cell & Bioscience, Vol 10, Iss 1, Pp 1-11 (2020)
Cell & Bioscience
Cell & Bioscience
Background Both testis and ovary can be produced sequentially in an individual with the same genome when sex reversal occurs in the teleost Monopterus albus, and epigenetic modification is supposed to be involved in gonadal differentiation. However,
Autor:
Yi Zhang, Zhiyuan Chen
Publikováno v:
Annual Review of Biochemistry. 89:135-158
DNA methylation at the 5-position of cytosine (5mC) plays vital roles in mammalian development. DNA methylation is catalyzed by DNA methyltransferases (DNMTs), and the two DNMT families, DNMT3 and DNMT1, are responsible for methylation establishment
Autor:
Xin Gu, Ling-Li Zhang, Yang Wen, Zhen Zhou, Yu-Ting Liu, Guoliang Xu, Ting Gong, Wei-Li Zhong, Jin-Qiu Zhou
Publikováno v:
Journal of Genetics and Genomics. 47:105-114
A nucleosome contains two copies of each histone H2A, H2B, H3 and H4. Histone H3 K4me0 and K36me3 are two key chromatin marks for de novo DNA methylation catalyzed by DNA methyltransferases in mammals. However, it remains unclear whether K4me0 and K3
Publikováno v:
Cancer Medicine
Cancer Medicine, Vol 10, Iss 16, Pp 5681-5695 (2021)
Cancer Medicine, Vol 10, Iss 16, Pp 5681-5695 (2021)
In patients with prostate cancer (PCa), there is a high rate of overdiagnosis and frequent overtreatment. Therefore, there is an urgent need for more accurate prediction of biochemical recurrence (BCR). DNA methylation regulation patterns play crucia
Publikováno v:
Journal of Oncology
Journal of Oncology, Vol 2021 (2021)
Journal of Oncology, Vol 2021 (2021)
There is a known link between DNA methylation and cancer immunity/immunotherapy; however, the effect of DNA methylation on immunotherapy in lung adenocarcinoma (LUAD) remains to be elucidated. In the current study, we aimed to screen key markers for
Autor:
Yuan Quan, Fengji Liang, Deqing Wu, Xueqing Yao, Zhihuang Hu, Yuexing Zhu, Ying Chen, Andong Wu, Danian Tang, Bingyang Huang, Ruifeng Xu, Zejian Lyu, Qian Yan, Lang Luo, Zhengzhi Ning, Yong Li, Jianghui Xiong
Publikováno v:
Frontiers in Oncology, Vol 10 (2020)
There is a body of evidence that the aging immune system is linked to cancer. In this study, with aging- and immune-related DNA methylation data, we investigated the DNA methylation regulation changes in promoters with other regions of genes during a
Publikováno v:
BMC Genomics
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
BMC Genomics, Vol 21, Iss 1, Pp 1-14 (2020)
Background Genes are regulated by various types of regulators and most of them are still unknown or unobserved. Current gene regulatory networks (GRNs) reverse engineering methods often neglect the unknown regulators and infer regulatory relationship
Publikováno v:
Food research international (Ottawa, Ont.). 142
The manufacturing process of tea (Camellia sinensis), especially oolong tea, involves multiple postharvest stresses. These stresses can induce the formation and accumulation of many important aroma compounds, such as indole-a key floral aroma contrib