A practical guide to cancer subclonal reconstruction from DNA sequencing

Autor: Quaid Morris, Amit G. Deshwar, Peter Van Loo, Paul C. Boutros, Adriana Salcedo, Maxime Tarabichi, David C. Wedge, Máire Ni Leathlobhair, Jeff Wintersinger

Publikováno v: Nature methods, vol 18, iss 2
Tarabichi, M, Salcedo, A, Deshwar, A G, Ni Leathlobhair, M, Wintersinger, J, Wedge, D C, Van Loo, P, Morris, Q D & Boutros, P C 2021, ' A practical guide to cancer subclonal reconstruction from DNA sequencing ', Nature Methods, vol. 18, no. 2, pp. 144-155 . https://doi.org/10.1038/s41592-020-01013-2
Nat Methods

Subclonal reconstruction from bulk tumor DNA sequencing has become a pillar of cancer evolution studies, providing insight into the clonality and relative ordering of mutations and mutational processes. We provide an outline of the complex computatio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f05d274be748f13fb495dcdb7b0ad6d7
https://escholarship.org/uc/item/0p64n4sf

Ethical considerations for modern molecular pathology

Autor: Vos, Shoko, van Diest, Paul J, Ausems, Margreet G E M, van Dijk, Marijke R, de Leng, Wendy W J, Bredenoord, Annelien L

Publikováno v: Journal of Pathology, 246(4), 405. John Wiley and Sons Ltd

Molecular pathology is becoming an increasingly important discipline in oncology as molecular tumor characteristics will increasingly determine targeted clinical cancer care. In recent years, many technological advances have taken place that contribu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::6ff99d93e3a408b0938b58e5865813ab
https://dspace.library.uu.nl/handle/1874/388470

Possible Role of GADD45γ Methylation in Diffuse Large B-Cell Lymphoma: Does It Affect the Progression and Tissue Involvement?

Autor: Barış İC, Caner V, Şen Türk N, Sarı İ, Hacıoğlu S, Doğu MH, Çetin O, Tepeli E, Can Ö, Bağcı G, Keskin A

OBJECTIVE: Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma among adults and is characterized by heterogeneous clinical, immunophenotypic, and genetic features. Different mechanisms deregulating cell cycle and apo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______3566::a696fc495359b899bbed2d16f298a37e

p53 as a potential predictive factor of response to chemotherapy: feasibility of p53 assessment using a functional test in yeast from trucut biopsies in breast cancer patients

Autor: S Bongard, E Lurati, Richard Iggo, Hervé Bonnefoi, S Movarekhi, A Ducraux, M F Pelte

Publikováno v: British Journal of Cancer
British Journal of Cancer, vol. 86, no. 5, pp. 750-755

Assessment of the predictive value of p53 requires the testing of large numbers of samples from patients enrolled in prospective phase III clinical trials. The goal of this study was to determine whether p53 status can be determined by p53 yeast func

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4c407ba6c5816d1f1826eef13a724291
http://europepmc.org/articles/PMC2375302

Virological and Molecular Characterisation of a New B Lymphoid Cell Line, Established from an AIDS Patient with Primary Effusion Lymphoma, Harbouring Both KSHV/HHV8 and EBV Viruses

Autor: Cadranel J, Elisabeth Macintyre, Lacoste, Eric Delabesse, Bestett G, Antoine M, Françoise Valensi, Antoine Gessain, Judde Jg

Publikováno v: Leukemia & lymphoma
Leukemia & lymphoma, 2000, 38 (3-4), pp.401-409. ⟨10.3109/10428190009087032⟩
Leukemia & lymphoma, Taylor & Francis, 2000, 38 (3-4), pp.401-409. ⟨10.3109/10428190009087032⟩

International audience; We report here a new case of primary effusion lymphoma (PEL), occurring in a French homosexual HIV-1 infected male with a pericardial, pleural and mesenteric tumour dissemination, and the establishment from his pleural effusio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0be944d5c21be133d67244e5f71678fc
https://doi.org/10.3109/10428190009087032