ParB proteins can bypass DNA-bound roadblocks via dimer-dimer recruitment

Autor: Tišma, Miloš, Panoukidou, Maria, Antar, Hammam, Soh, Young-Min, Barth, Roman, Pradhan, Biswajit, Barth, Anders, van der Torre, Jaco, Michieletto, Davide, Gruber, Stephan, Dekker, Cees

Publikováno v: Science advances, vol. 8, no. 26, pp. eabn3299

The ParABS system is essential for prokaryotic chromosome segregation. After loading at parS on the genome, ParB (partition protein B) proteins rapidly redistribute to distances of ~15 kilobases from the loading site. It has remained puzzling how thi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::853950444c88426dc557acea9cddc9d6
https://pubmed.ncbi.nlm.nih.gov/35767606

Vibrio cholerae chromosome 2 copy number is controlled by the methylation-independent binding of its monomeric initiator to the chromosome 1 crtS site

Autor: Maria-Vittoria Mazzuoli, Marie-Eve Val, Florian Fournes, Francisco de Lemos Martins, Didier Mazel

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, 2018, 46 (19), pp.10145-10156. ⟨10.1093/nar/gky790⟩
Nucleic Acids Research, Oxford University Press, 2018, 46 (19), pp.10145-10156. ⟨10.1093/nar/gky790⟩

International audience; Bacteria contain a primary chromosome and, frequently , either essential secondary chromosomes or dispensable megaplasmids of plasmid origin. Incoming plasmids are often poorly adapted to their hosts and their stabilization re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7512d0739ff49b3f282e9969f7b52d2c
https://hal-pasteur.archives-ouvertes.fr/pasteur-02890948/document

DNA binding specificities of Escherichia coli Cas1–Cas2 integrase drive its recruitment at the CRISPR locus

Autor: Clara, Moch, Michel, Fromant, Sylvain, Blanquet, Pierre, Plateau

Publikováno v: Nucleic Acids Research
Nucleic Acids Research, Oxford University Press, 2017, 45 (5), pp.2714-2723. ⟨10.1093/nar/gkw1309⟩

International audience; Prokaryotic adaptive immunity relies on the capture of fragments of invader DNA (protospacers) followed by their recombination at a dedicated acceptor DNA locus. This integrative mechanism, called adaptation, needs both Cas1 a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7b04918c8d792275773b9db6629f7fc5
https://hal-polytechnique.archives-ouvertes.fr/hal-01961608/document

DNA supercoiling and its role in DNA decatenation and unknotting

Autor: Guillaume Witz, Andrzej Stasiak

Publikováno v: NUCLEIC ACIDS RESEARCH
Nucleic Acids Research
Nucleic Acids Research, vol. 38, no. 7, pp. 2119-2133

Chromosomal and plasmid DNA molecules in bacterial cells are maintained under torsional tension and are therefore supercoiled. With the exception of extreme thermophiles, supercoiling has a negative sign, which means that the torsional tension dimini

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f1efe3323551ca5aeba398b63e5e2c71

Staphylococcus epidermidis SrrAB regulates bacterial growth and biofilm formation differently under oxic and microaerobic conditions

Autor: Di Qu, Adrien Nicolas Fischer, Li Bai, Huayong Liu, Tao Zhu, Patrice Francois, Tao Xu, Haiyan Han, Yang Wu, Friedrich Götz, Youcong Wu

Publikováno v: Journal of Bacteriology, Vol. 197, No 3 (2015) pp. 459-76

SrrAB expression in Staphylococcus epidermidis strain 1457 (SE1457) was upregulated during a shift from oxic to microaerobic conditions. An srrA deletion (Δ srrA ) mutant was constructed for studying the regulatory function of SrrAB. The deletion re

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::127aec57f94890504459beeaf88039dc
https://archive-ouverte.unige.ch/unige:74130